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Abstract Background A subset of horses deficient in alpha‐tocopherol (α‐TP) develop muscle atrophy and vitamin E‐responsive myopathy (VEM) characterized by mitochondrial alterations in the sacrocaudalis dorsalis m...

Abstract Nontraumatic adrenal hemorrhage (NTAH) has been associated with stress‐induced catecholamines release in underlying conditions such as sepsis and recent surgery in humans. It can lead to primary hypoadrenocort...

Abstract Background The prevalence of clinical signs and factors triggering muscle atrophy and rhabdomyolysis associated with an MYH1E321G mutation in Quarter Horses and related breeds (QH) remain poorly understood. Hypo...

Abstract Background Increased gene transcription of hypoxia‐induced mediators of fibrosis in renal tissue has been identified in experimentally induced, ischemic chronic kidney disease (CKD). Objective To characterize ...

Abstract Background Skeletal dysplasia encompasses a heterogeneous group of genetic disorders characterized by an abnormal development of bones, joints, and cartilage. Two Chianina half‐sibling calves from consanguineo...

Abstract Background Limited information is available regarding the clinical features, treatment, and prognosis of neosporosis in adult dogs. Objective Describe the clinical signs, laboratory findings, magnetic resonance ...

Abstract Background Paramyotonia congenita and Brody disease are well‐described conditions in humans, characterized by exercise‐induced myotonic‐like muscle stiffness. A syndrome similar to Brody disease has been r...

Abstract Background Peripheral nerve sheath tumors (PNSTs) are a group of neoplasms originating from Schwann cells or pluripotent cell of the neural crest. Therapeutic options and prognosis are influenced by their degree...

Abstract Objective Describe the clinical course and diagnostic and genetic findings in a cat with X‐linked myotubular myopathy. Case Summary A 7‐month‐old male Maine coon was evaluated for progressively worsening g...