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Quantitative Structure Activity Relationship (QSAR) studies were carried out for a series of 16 compounds which acts as ligands for PPAR-γ receptor. TSAR software was used to identify the essential structural and physic...

4-methyl-3-(6-{[arylmethylene] amino} pyridin-3-yl)-2H-chromen-2-one derivatives containing different functional groups have been synthesized and screened for their antibacterial activity against four different strains o...

Metformin hydrochloride (MH), an important drug in the treatment of type II diabetes mellitus, requires multiple administration in 500-1500 mg doses/day. Sustained release gastro retentive multiparticulates of MH were pr...

The cooperative and collaborative work between Universities and Libraries are key points for teachers, researchers and students to make progress in their studies and research. The Library Linkage Initiative has pursued t...

Las expectativas que los ciudadanos, las empresas y otros grupos de interés tienen sobre el gobierno electrónico y sus aplicaciones específicas tienen un impacto en las decisiones sobre el uso de tecnologías de infor...

Se propone una metodología analítica selectiva, dirigida a estudiar la absorción gastrointestinal de ciprofloxacina, utilizando modelos in vitro que operen con membranas naturales. El método consiste en diferenciar, ...

Agents repesent a new paradigm for developing software applications. In spite of the interest of this particular way of looking at problems, there is considerable discrepancy on exactly what is an agent and which are the...

For centuries, experimentation has been at the center of all successful scientific studies. Experimental explorations can offer new perceptions, weed out unproductive approaches and validate theories and practices. Compu...

The computational resources need by the scientific community to solve problems is beyond the current available infrastructure. Performance requirements are needed due constant research progress, new problems studies or d...

A series of structurally similar isatin analogues with antitubercular activity have been subjected for 2D and 3D QSAR analysis using V life MDS 3.5 software. The compounds were divided into training and test set of 44 an...