Buscar recursos académicos

Abstract Background The roles of pharmacists have changed in recent times, with pharmacists advancing public health through immunization. Objective This study aimed to evaluate community pharmacists’ knowledge, attitud...

Abstract Objectives Childhood immunization remains one of the most effective public health interventions, yet coverage gaps persist in northern Nigeria. This study assessed parental knowledge, attitudes, and sociocultura...

Abstract Introduction Varicella, caused by the varicella zoster virus, poses a significant public health challenge, particularly among children. To address this, the city of Shenzhen, China, introduced a publicly funded ...

BackgroundZero-dose children represent a major public health challenge in low-income countries. In 2024, the Nkolndongo Health District in Yaoundé, Cameroon, recorded the highest number of zero-dose children in the coun...

Abstract Introduction Invasive meningococcal disease (IMD) caused by meningococcal serogroup B (MenB) is a rare but serious illness with potentially life-threatening outcomes, particularly in infants. In Brazil, IMD is ...

Abstract Introduction Respiratory syncytial virus (RSV) poses a significant health risk to older adults, particularly those with chronic comorbidities, in the Gulf Cooperation Council (GCC) countries. Despite its high bu...

Abstract Introduction Bordetella pertussis infections have resurged globally, posing notable public health challenges, particularly in pediatric populations. Poland remains the only EU country that continues to use the w...

BackgroundNew vaccine approaches are needed against tuberculosis (TB). We sought to optimize mucosal immunogenicity and protective efficacy by modulating the adjuvant component and route of immunization of a next-generat...

Early-life vaccinations often yield short-lived antibody (Ab) responses due to limited germinal center (GC) reaction and plasma cell (PC) survival. The aim of the study was to assess how vaccine delivery routes (homologo...

Abstract Background Vaccine refusal is a growing public health concern, threatening herd immunity and the control of vaccine-preventable diseases. The COVID-19 pandemic has influenced healthcare delivery and vaccine refu...

Abstract Introduction Tuberculosis (TB) affects over 10 million people worldwide annually, is difficult to treat, and is a major cause of death. The M72/AS01E candidate vaccine is the first vaccine in over 100 years wit...

Porcine circovirus-associated disease (PCVAD), caused by pathogenic porcine circovirus type 2 (PCV2), remains one of the most economically devastating diseases in the global swine industry, and the continued emergence an...

Abstract BackgroundWith the advent of new vaccines, including the COVID-19 vaccines introduced during the recent pandemic, the need for near real-time active surveillance has increased to support timely regul...

mRNA vaccines emerged as a leading vaccine technology during the COVID-19 pandemic. However, their sustained protective efficacies were limited by relatively short-lived antibody responses and the emergence of SARS-CoV-2...

Abstract Objective The escalating threat of antimicrobial resistance poses significant clinical challenges, particularly in cases of co-infections involving Staphylococcus aureus (SA) and Pseudomonas aeruginosa (PA), ...

Introduction Six years later, the impact of the COVID-19 pandemic on children in Latin America remains profound. Even though they were considered less susceptible to the disease, infants have emerged as one of the most a...

Abstract Objective To compare the differential activation characteristics of Toll-like receptor 5 (TLR5) agonist KFD and Toll-like receptor 7 (TLR7) agonist R837 on nasal epithelial cells (NECs) and bone marrow-derive...

Abstract Objective High-altitude chronic hypoxia can alter the immune status, yet the immune regulatory characteristics of various vaccine adjuvants in this environment remain to be fully elucidated. Accordingly, emph...

Abstract Current lipid nanoparticles (LNPs) used in mRNA vaccines typically incorporate polyethylene glycol (PEG) as a stabilizing material; however, safety concerns have prompted the search for non-PEG alternatives. Sev...

Abstract Cervical cancer remains a major public health problem, particularly in low- and middle-income countries, and persistent human papillomavirus (HPV) infection is its primary cause. In Tunisia, the HPV vaccine was ...

Resumen: A cinco años de la implementación de la Estrategia Mundial de la OMS para la eliminación del cáncer cervicouterino, Chile muestra avances relevantes en los tres pilares definidos: inmunización, tamizaje y t...

Abstract Objective Klebsiella pneumoniae (Kp) is a clinically prevalent opportunistic pathogen, with escalating antimicrobial resistance posing substantial challenges. Current vaccine strategies are constrained by the...

Animal-bite and scratch visits to the emergency department (ED) often require time-sensitive decisions on rabies post-exposure prophylaxis (PEP) alongside tetanus prevention. In China, recent national standards and local...

ABSTRACT Background and Aims Hepatitis B is a serious, communicable liver disease resulting from hepatitis B virus infection. Healthcare workers (HCWs), including nursing students, are at elevated risk of exposure. We as...