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Colección compuesta por 28 boletines impresos editados por la Fundación Instituto Leloir durante el período 2004-2016 y que, al registrar diferentes aspectos de su quehacer, permiten dar continuidad a la colección Me...

Fil: Buch, Alfonso. Universidad de Buenos Aires. Facultad de Ciencias Sociales; Argentina. Entre Prometeo y la bioquímica argentina, un sabio amable, Luis Federico Leloir, responde a la pregunta de por qué ha investiga...

original Fil: Cardinale, Hernán. Fil: Pregliasco, Sebastián.

original Fil: Leloir, Luis Federico. Instituto de Investigaciones Bioquímicas Fundación Campomar; Argentina blanco y negro

original Fil: Leloir, Luis Federico. Instituto de Investigaciones Bioquímicas Fundación Campomar ahora Fundación Instituto Leloir; Argentina Fil: Parodi, Armando José A.. Instituto de Investigaciones Bioquímicas Fun...

original Fil: Staneloni, Roberto Julio. Instituto de Investigaciones Bioquímicas Fundación Campomar; Argentina Fil: Tolmasky, Marcelo E.. Instituto de Investigaciones Bioquímicas Fundación Campomar; Argentina

original Fil: Trucco, Raúl E.. Instituto de Investigaciones Bioquímicas Fundación Campomar; Argentina Fil: Cardini, Carlos E.. Instituto de Investigaciones Bioquímicas Fundación Campomar; Argentina

Dengue is the single most important human viral infection transmitted by insects. The function of the viral proteins andtheir interactions with the host cell is under exhaustive investigation with the aim of identifying ...

Galactosemia involves different forms of inborn errors of metabolism affecting galactose processing. Different from type 1 and type 2, respectively, related to GALT and GALK1 defects, type 3 galactosemia is due to bialle...

We report the emergency development and application of a robust serologic test to evaluate acute and convalescent antibody responses to SARS-CoV-2 in Argentina. The assays, COVIDAR IgG and IgM, which were produced and pr...

Protein recognition of DNA sites is a primary event for gene function. Its ultimate mechanistic understanding requires an integrated structural, dynamic, kinetic, and thermodynamic dissection that is currently limited co...

Glucosidase II (GII) plays a key role in glycoprotein biogenesis in the endoplasmic reticulum (ER). It is responsible for the sequential removal of the two innermost glucose residues from the glycan (Glc(3)Man(9)GlcNAc(2...

During aging, the brain undergoes changes that impair cognitive capacity and circuit plasticity, including a marked decrease in production of adult-born hippocampal neurons. It is unclear whether development and integrat...

Leukemia inhibitory factor (LIF) and oncostatin M (OSM) induce DNA synthesis in Swiss 3T3 cells through common signaling mechanism(s), whereas other related cytokines such as interleukin-6 and ciliary neurotrophic factor...

MISTIC (mutual information server to infer coevolution) is a web server for graphical representation of the information contained within a MSA (multiple sequence alignment) and a complete analysis tool for Mutual Informa...

Mediator 17 (MED17) is part of the head of the Mediator complex, which regulates transcription initiation indifferent eukaryotic organisms, including plants. We have previously characterized MED17 roles in Arabidopsispla...

Dengue virus RNA-dependent RNA polymerase specifically binds to the viral genome by interacting with a promoter element known as stem-loop A (SLA). Although a great deal has been learned in recent years about the functio...

Sterol regulatory element binding proteins (SREBP), encoded by the Srebf1 and Srebf2 genes, are important regulators of genes involved in cholesterol and fatty acid metabolism. Whereas SREBP-2 controls the cholesterol sy...

HOP (HSP70-HSP90 organising protein) is a conserved family of co-chaperones well known in mammals for its role in the folding of signalling proteins associated with development. In plants, HOP proteins have been involved...

In toxicity and pharmacological studies C. elegans are exposed to different compounds and the effects analyzed by observing worm viability or behavior. An alternative approach is to use locomotor activity as a readout, w...

Reciprocal activation of flexor and extensor muscles constitutes the fundamental mechanism that tetrapod vertebrates use for locomotion and limbdriven reflex behaviors. This aspect of motor coordination is controlled by ...

Lección conmemorativa Carlos Jiménez Díaz instituida en memoria del insigne maestro de la medicina cuya vida estuvo íntegramente dedicada a la docencia e investigación. original manuscrita Fil: Leloir, Luis Federico...

Manuscrito original, digitalizado en páginas individuales. Fil: Leloir, Luis Federico. 1 cuaderno

Fil: Lorenzano, César. Universidad Nacional de Tres de Febrero; Argentina. Réplica al comentario bibliográfico de Alfonso Buch del libro: Por los caminos de Leloir. Estructura y desarrollo de una investigación Nobel ...