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In spite of their central role in orchestrating immunity, dendritic cells (DCs) can also limit harmful reactions and promote immune tolerance by inducing T cell anergy or favoring the differentiation of T regulatory (Tre...

The interplay between thyroid hormone action and the immune system has been established in physiological and pathological settings. However, their connection is complex and still not completely understood. The thyroid ho...

Dimitra Peppa,1–3 Aljawharah Alrubayyi,1,4 Sanjay Bhagani1,5 1Division of Infection and Immunity, University College London, London, UK; 2Mortimer Market Centre, Department of HIV, CNWL NHS Trust, London, UK; 3...

The article presents the results of a study of the influence of adverse microclimate parameters on the morphological and immunological blood parameters of piglets in the neonatal period of development, and also evaluates...

Abstract Background Cancer immunotherapy has revolutionized the clinical management of cancer due to its promising survival benefits. Although FDA-approved cancer immunotherapy primarily leverages adaptive immunity for t...

Chemokine network is central to the innate and adaptive immunity and entails a variety of proteins and membrane receptors that control physiological processes such as wound healing, angiogenesis, embryo growth and develo...

Abstract Background The role of inflammation-induced myeloid-biased hematopoiesis in driving resistance to immune checkpoint blockade (ICB) is recognized, yet the intricate mechanisms through which tumors orchestrate it ...

Background: Helja is a sunflower lectin that recognizes mannose motifs. Candidiasis is a fungal infection caused by Candida spp. that affects immunocompromised individuals. This opportunistic yeast can be recognized by d...

Bone infection is a severe disease caused by microbial invasion of bone tissue, characterized by inflammatory responses, bone destruction, and impaired repair. Its high recurrence rate and refractory nature have posed si...

Cu, a common essential trace element in the human body, is involved in multiple physiological and pathological processes. Cuproptosis, a recently proposed form of cell death, is triggered by Cu overload. It primarily tar...

Dendritic cell (DC) and natural killer (NK) cell interactions are important for the regulation of innate and adaptive immunity, but their relevance during early pregnancy remains elusive. Using two different strategies t...

La rápida propagación del coronavirus SARS-CoV-2, agente causal de la enfermedad pandémicaemergente COVID-19 y sus nuevas variantes, requiere del compromiso de la comunidad inmunológicapara comprender la magnitud y n...

Abstract The CRISPR‐Cas system constitutes an adaptive immune mechanism in prokaryotes that defends against mobile genetic elements. Within the perpetual co‐evolutionary arms race between bacteria and their viral pre...