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IntroductionDelayed cerebral ischemia (DCI) is one of the main causes of disability and death following surgical treatment of ruptured intracranial aneurysms. Many studies combine data from patients undergoing clipping a...

IntroductionDisrupted rest-activity rhythm (RAR), an accelerometer-derived measure of the strength and temporal organization of daily behavioral rhythms, has been linked to multiple adverse health outcomes. Given that th...

BackgroundSubarachnoid hemorrhage (SAH) from ruptured intracranial aneurysms is a severe stroke subtype with a high mortality rate. Statins, noted for cholesterol-independent benefits, are being studied as potential trea...

Abstract Objective Posterior communicating artery aneurysm(PCoAA) exhibit complex anatomical relationships, and microsurgical clipping of large or posteromedially projecting aneurysms remains technically challenging w...

Abstract Left atrial appendage (LAA) aneurysm is a rare structural abnormality that can predispose to significant complications, including systemic embolism and complex supraventricular arrhythmias. Here, we report a 44-...

Abstract Abdominal aortic aneurysm (AAA) is a common cardiovascular disease resulting in high mortality rate due to rupture. Intraluminal thrombus (ILT) is involved in AAA progression via both biomechanically protective ...

Polycythemia vera (PV) is a JAK2-mutated myeloproliferative neoplasm associated with thrombotic and vascular complications. Giant cell arteritis (GCA) is a granulomatous large-vessel vasculitis that may involve the aorta...

Abstract Background Cancer treatments such as chemotherapy and radiotherapy significantly impact the cardiovascular system. While cardiac toxicity is well characterized, the effects on the aorta, the body’s largest art...

Abstract Background Kawasaki disease (KD) is an acute systemic vasculitis of childhood and the leading cause of acquired heart disease in children in developed countries. Infants frequently present with incomplete diseas...

Aortic diseases (aortic aneurysm, aortic dissection, atherosclerosis) represent a substantial clinical and economic burden due to the lack of effective early diagnostic tools and mechanism-based therapies. Metabolomics, ...

Abstract Background Although the field of minimally invasive aortic surgery is steadily progressing across India, the adoption of totally endoscopic techniques remains in its nascent phase, limited to a handful of centre...

Coronary artery ectasia (CAE) is a vascular lesion characterized by abnormal dilation of the coronary arteries, with complex pathogenesis and diverse clinical manifestations. CAE can be classified into primary and second...

BackgroundHyper IgE syndrome from dominant-negative STAT3 mutations is a multisystem disease with vascular complications. Following a myocardial infarction (MI) from a coronary artery aneurysm in a 43-year-old patient, o...

Abstract Background The contact activation system is triggered when blood comes into contact with artificial surfaces. Cardiopulmonary bypass (CPB) induces such activation, however the extent of factor XII (FXII) reducti...

Abstract Objectives This study aimed to assess the agreement between carotid Doppler ultrasound (CDU) and high-resolution magnetic resonance imaging (HRMRI) in the evaluation of extracranial internal carotid artery disse...

STAT1 gain-of-function (GoF) is an inborn error of immunity characterized by a common feature of chronic mucocutaneous candidiasis and variable additional clinical manifestations, including recurrent bacterial and viral ...

Abstract Subarachnoid hemorrhage (SAH) is an extremely lethal cerebrovascular emergency that can lead to severe long term neurological deficits. Modern research evidence indicates that the incidence of SAH varies signifi...

Vascular and metabolic diseases, including atherosclerosis, aortic aneurysm and dissection, obesity, type 2 diabetes, and metabolic dysfunction–associated steatotic liver disease (MASLD), constitute a major global heal...