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Background. Viral infections remain a major global health threat despite advances in vaccines and antiviral drugs due to the rapid emergence of resistance and new viral pathogens. Antiviral peptides (AVPs) are promising ...

Several studies have been published regarding the interaction between the spike protein of the novel coronavirus SARS-CoV-2 and ACE2 receptor in the host cells. In the presente work, we evaluated the in silico properties...

Abstract The research article reports a simple strategy through Vilsmeier Haack formylation for the synthesis of ethyl 1-formyl-1,2,3,6-tetrahydro-4-methyl-2-oxo/thioxo-6-phenylpyrimidine-5-carboxylates. The most facile ...

Abstract Background Little is known about health-related quality of life (HRQoL) in immunocompromised people during and after COVID-19 illness. We describe HRQoL outcomes from the EPIC-IC trial, which included participan...

Hepatitis C virus (HCV) infection in patients with chronic kidney disease (CKD) is a major cause of morbidity and mortality. HCV infection is associated with some glomerular disease. It also has a high incidence in patie...

The incidence of chronic hepatitis C virus (HCV) infection in kidney transplant recipients is 5%-15%, and HCV is an important risk factor for posttransplant kidney issues. Novel interferon-free regimens with direct-actin...

Tenofovir is one of the first-line new generation antiviral agents commonly used in chronic hepatitis B treatment. While being considered an effective and safe treatment, the most important side effect known is nephrotox...

Coronavirus disease 2019 (COVID-19) presents with a wide spectrum of clinical manifestations. While primarily affecting the respiratory system, neurological involvement and thromboembolic complications have also been doc...

New direct acting antiviral agents are quite effective in treating hepatitis-C virus infection (HCV). Treating HCV that occurs or relapses after kidney transplantation necessitates a heedful approach for selecting the ...

Rinovirus y Enterovirus (polio, coxsackie, echovirus) son los dos tipos de picornavirus responsables del alto número de infecciones virales en humanos como el resfrío (o la gripe). Datos de Relación Estructura Activid...

Fil: Gregoric, Juan José. Universidad de Buenos Aires. Facultad de Filosofía y Letras. Instituto de Ciencias Antropológicas; Argentina. En este trabajo, analizamos el activismo de personas afectadas por el VIH-sida en...

Los flavonoides son importantes constituyentes de la dieta humana y se encuentran en vegetales, frutas y bebidas como el té y el vino. Son compuestos fenólicos de baja toxicidad, aunque se ha informado que poseen algun...

Debido a la astringencia que manifiesta Maytenus vitis-idaea Griseb. (Celastraceae), se abordó el estudio de los taninos condensados presentes en los extractos acuosos obtenidos de hojas frescas y secas, determinándose...