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Aortic diseases (aortic aneurysm, aortic dissection, atherosclerosis) represent a substantial clinical and economic burden due to the lack of effective early diagnostic tools and mechanism-based therapies. Metabolomics, ...

Study objective: To evaluate whether impaired ventriculo-aretrial interaction characterizes chronic ischemic heart disease (CIHD) caused by stable chronic obstructive coronary artery disease (CAD), using wave intensity a...

Abstract Pheochromocytomasand paragangliomas (collectively referred as PPGLs) are highly heritable neoplasms arise from chromaffin cells of neural crest tissues; 40% of patients with PPGLs harbour germline pathogenic var...

Abstract Background Postoperative complications in patients with acute type A aortic dissection (ATAAD) significantly affect their prognosis. This study investigates the association between cardiopulmonary bypass(CPB) we...

Objective To explore the number of peripheral blood regulatory T cells (Treg) in patients with chronic kidney disease (CKD) and its correlation with vascular calcification. Methods This was a single-center, cross-section...

ABSTRACT Background Myxomatous mitral valve disease (MMVD) can cause pulmonary hypertension (PH). Mitral valve repair (MVR) has been described as a surgical treatment option for MMVD, but the benefit of MVR when PH is pr...

Abstract Abdominal aortic aneurysm (AAA) is a common cardiovascular disease resulting in high mortality rate due to rupture. Intraluminal thrombus (ILT) is involved in AAA progression via both biomechanically protective ...

Abstract Background Aortic and aortoiliac thrombosis in dogs causes disease and death. Objective To describe the procedure and outcomes for stenting the caudal aorta and aortoiliac trifurcation. Animals Seven client‐ow...

BackgroundRecurrent bacterial pneumonia accompanied by atypical systemic findings may indicate an uncharacterized inborn error of immunity (IEI). We report a 10-year-old male with recurrent pneumonias, mildly low but fun...

Abstract Background Endothelial cells (ECs) orchestrate vascular homeostasis and resilience but can undergo reprogramming into a mesenchymal-like phenotype through an endothelial-to-mesenchymal transition (EndMT). Crucia...

Vascular and metabolic diseases, including atherosclerosis, aortic aneurysm and dissection, obesity, type 2 diabetes, and metabolic dysfunction–associated steatotic liver disease (MASLD), constitute a major global heal...

Renal artery disease is frequently encountered as an incidental finding in peripheral vascular disease. In this case report, a 67- year-old lady with peripheral vascular and renal artery lesions identified at a time befo...

Background: Fetuin-A is a negative acute-phase reactant which prevents vascular calcification. Coronary artery disease (CAD) is the most important cause of mortality in patients undergoing renal replacement therapy (RRT)...

Abstract Background Most endometrial cancers (75%) are diagnosed in early stages (stages I and II), in which abnormal uterine bleeding is the most frequent clinical sign.When the diagnosis is performed in stage IV, the...

Abstract Background Phenotypic switching of vascular smooth muscle cells (VSMCs) is a hallmark of coronary artery disease (CAD). How type 2 diabetes mellitus (T2DM), a major risk factor for cardiovascular complications, ...

Preservation of pelvic perfusion during endovascular repair of aortoiliac aneurysmal disease is clinically significant, especially in patients with contralateral internal iliac artery (IIA) occlusion. Although iliac bran...

Abstract Background Small cell carcinoma is a highly aggressive neuroendocrine malignancy that most commonly arises in the lungs, gastrointestinal tract, or pancreas. Primary small cell neuroendocrine carcinoma of the en...

Vascular calcification arises from osteogenic transdifferentiation of vascular smooth muscle cells (VSMC) driven by disordered calcium signaling. Sarcoplasmic/ER calcium ATPase 2 (SERCA2) maintains intracellular calcium ...

Laurence-Moon-Biedl syndrome (LMBS) is a rare autosomal recessive disease which is characterized by obesity, mental retardation, retinitis pigmentosa, polydactyly and hypogonadism. Here in we discussed a patient with LMB...

Phytoestrogens (PE) such as genistein (Gen) are considered a natural therapy to counteract the risk of cardiovascular diseases in postmenopausal women. Atherosclerosis is a chronic inflammatory process that, in the later...