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Rhizoma Paridis saponins (RPS) were considered to be the principal bioactive components of Paris polyphylla Smith var. yunnanensis. Intestinal microflora-mediated metabolism may affect their pharmacological activities in...

Arsenic (As) is a toxic metalloid, and its accumulation in macroalgae has raised concerns for aquatic ecosystem health and human food safety given the increasing consumption of macroalgae. While previous studies have pre...

Eighteen (3R) and (3R,4R)-N-phenyl-, N-phenylalkyl and N-arylsuccinimides were prepared with high enantioselectivity by biotransformation of maleimides with A. fumigatus. This environmentally friendly, clean and economic...

Abstract Research on garlic peel has identified a variety of bioactive compounds. This study highlights the significance of garlic peels and the marine fungal strain Paecilomycesmaximus PQ584815 in generating secondary m...

The liver is the main place for phase II metabolism and transport of xenobiotics mediated by Mrp2, leading to elimination of conjugated metabolites into bile. In the gastrointestinal tract, phase II enzymes and Mrp2 are ...

In the last years, hairy root (HR) cultures are gaining attention in the biotechnology industry. This particular plant cell culture derives from explants infected with Agrobacterium rhizogenes. They constitute a relative...

Abstract Trehalose 6-phosphate (T6P), often referred to as plant insulin, serves as a central signaling molecule that regulates carbon partitioning and sucrose flux in plants, thereby influencing key agronomic traits, su...

The oral administration of macrocyclic lactones to sheep leads to poorer efficacy and shorter persistence of the antiparasitic activity compared to the subcutaneous treatment. Gastrointestinal biotransformation occurring...

Accelerating the composting of organic waste remains a key objective in research and practice. This review aims to critically examine recent advancements in microbial inoculation (MI) strategies and their role in enhanci...

Per- and polyfluoroalkyl substances (PFAS) are highly persistent environmental contaminants that pose potential ecological and health risks to humans and wildlife. This study investigated the comparative toxicity of four...

Abstract Arginine, an amino acid, is being increasingly widely applied in various fields, including cosmetics, pharmaceuticals, food, and agriculture. Arginine was produced from microbial fermentation of agro-industry ca...

O objetivo deste trabalho foi verificar a relação entre a presença de clorpromazina e seus produtos de biotransformação com resultados indicativos de presença de anfetaminas (ANF) pelo imunoensaio enzimático homog...

Las características conformacionales y electrónicas del acido valproico (vpa), valpramida (vpd), valproato de etilo (evp), valproato de propilo (pvp), valproato de butilo (bvp), valproato de isobutilo (ibvp) y valproat...

Se revisó el tema de interacciones medicamentosas para compilar información necesaria para la práctica médica. Se describen varias clasificaciones de interacciones enfatizando en la clasificación según mecanismos d...