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Depression and burnout are linked to a higher risk for the development of cardiovascular diseases. Physical activity has the potential to enhance prognosis of cardiovascular diseases and improve depression and burnout sy...

Cardiovascular, respiratory, and related disorders (CVRDs) are the leading causes of adult death worldwide, and substantial inequalities in care of patients with CVRDs exist between countries of high income and countries...

Background Acute exacerbations (AEs) drive disease progression and healthcare burden in chronic obstructive pulmonary disease (COPD). Although prior AE history is the strongest predictor of future events, it cannot guide...

ObjectiveTo develop a Health Action Process Approach (HAPA) based exercise rehabilitation program for chronic heart failure (CHF) patients and evaluate its effectiveness.MethodsA randomized controlled trial was carried o...

Abstract Background With the widespread adoption of percutaneous coronary intervention (PCI), patients experiencing acute myocardial infarction (AMI) complicated by ventricular arrhythmia (VA) continue to encounter a sig...

Abstract Background Cardiovascular diseases (CVDs) continue to be the leading cause of mortality worldwide, accounting for approximately 19.8 million deaths in 2022, with ischemic heart disease and stroke responsible for...

Lipoprotein(a) [Lp(a)] is a useful marker for cardiovascular risk stratification. Previous studies have shown higher Lp(a) levels in women than in men and sex differences in its association with atherosclerosis. The aim ...

Abstract Background Sub-Saharan Africa (SSA) has been witnessing a persistent increase in the burden of cardiovascular diseases (CVD), such as stroke and heart disease, over several decades. A key driver of this burden h...

ObjectiveEpidemiological studies show an increased risk for premature maternal cardiovascular disease in women after pregnancy complications, like preeclampsia, gestational hypertension and gestational diabetes mellitus....

Advances in perinatal and neonatal medicine have dramatically improved the survival rates of infants with perinatal vulnerabilities of preterm birth (PTB), low birth weight (LBW) or small for gestational age (SGA), by re...

Phα1β, a peptide toxin purified from Phoneutria nigriventer spider venom, has a dual antinociceptive effect, inhibiting high-voltage-activated calcium channels and antagonising the TRPA1 receptor that differentiates it...

Micronutrient undernutrition during critical periods of growth has become an important health issue in developing and developed countries, particularly among pregnant women and children having an imbalanced diet. Zinc is...

Abstract Background Kidney injury (KI) has been documented in dogs treated with furosemide for left‐sided congestive heart failure (CHF). Hypothesis/Objectives Determine risk factors for development of KI in furosemide...

Tianqing Zhang,1 Sijie Xiao,2 Yanfu Xia,3 Kun Chen,1 Honglan Liu,1 Ping Zhang,1 Li Luo1 1Department of Cardiology, Changde Hospital, Xiangya School of Medicine, Central South University (The First People’s Hospital of ...

Abstract Current treatment for atherosclerotic cardiovascular diseases (ASCVD) mainly focuses on the modification of systemic risk factors, such as hyperglycemia and hyperlipidemia. Despite significant efforts and expans...

Copper is an essential trace element in the human body, extensively involved in key physiological and biochemical processes such as antioxidant defense, energy metabolism, neural signaling, and immune regulation. In rece...

Abstract BackgroundMany persons with type 2 diabetes (T2D) lack risk awareness or underestimate their cardiovascular risk. Although health care professionals in primary health care strive to implement risk-aw...

Platelets play a crucial role in atherothrombosis, as demonstrated by the effectiveness of the antiplatelet agent aspirin (acetylsalicylic acid, ASA) in the secondary prevention of cardiovascular disease. Low-dose aspiri...

BackgroundTo develop and externally validate a coronary heart disease (CHD) risk model from routine clinical indicators and identify key predictors.MethodsThe Framingham Heart Study cohort (n = 4,240) was used. Missi...

Introduction Diabetic peripheral neuropathy (DPN) is a common, underdiagnosed and irreversible complication of diabetes mellitus. However, limited evidence exists on the drivers of DPN in Asian populations, particularly ...

Abstract Background Development of a telmisartan‐based suppression test may facilitate the diagnosis of primary hyperaldosteronism (PHA) in cats, which remains difficult today. Objectives To develop a telmisartan suppr...

Abstract Background Typical atrioventricular accessory pathways (APs) are composed of myocardial cells. They provide electrical connections between atria and ventricles separate from the normal conduction system. Accesso...

BackgroundObesity is a major risk factor for lipotoxic cardiomyopathy, a process involving lipid metabolism disorders, inflammatory responses, and mitochondrial dysfunction. Salvia miltiorrhiza (Danshen), a traditional C...

Endothelial glycocalyx dysregulation remains the leading cause of the development and progression of cardiovascular diseases, which can increase the risk of organ failure and even cause death. However, the construction o...