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IntroductionThe limited availability of suitable scaffolds for three-dimensional (3D) cell culture has driven the development of new biomaterials. In this study, we developed a porcine fibrin matrix gel (PFMG) derived en...

The development of anti-CD3 antibody-based T cell engager therapeutics has improved the treatment of various malignancies, yet the challenge of achieving tumor-specific targeting while minimizing on-target off-tumor effe...

Abstract Modern agriculture requires rapid, affordable tools to monitor crops and soils directly in the field. Cellulose, the structural polymer of plants, is emerging as a versatile foundation for lightweight, biodegrad...

Cancer therapy and food preservation both face significant challenges related to stability, targeted delivery, safety, and efficiency of active compounds. Biopolymer-based nanoparticles, particularly those derived from c...

Abstract Bone fracture healing requires coordinated regulation of osteogenesis, angiogenesis, and immune homeostasis within a dynamically evolving microenvironment. However, current biomaterials rarely integrate these th...

Human induced pluripotent stem cells (iPSCs) are transforming adoptive cell therapy by combining unlimited self-renewal, broad differentiation potential, and high amenability to genome engineering. These attributes make ...

Abstract Background Chinese hamster ovary (CHO) cells are pivotal in biopharmaceutical production, yet balancing high recombinant protein yield with cell survival remains challenging. While previous studies have targeted...

Abstract Intracerebral hemorrhage (ICH) is a devastating neurological condition with high mortality and morbidity. Despite advancements in medical and surgical treatments, the long-term prognosis of ICH remains poor. Ste...

ABSTRACT Constructing ternary blends has been considered as a feasible approach to achieve highly efficient organic solar cells; however, the delicate choice of the guest components still needs labor‐intensive and time...

This study aims to examine the role of exosomes derived from human urine-derived stem cells (hUSCs-Exo) in the in vitro construction of a composite structure comprising hUSCs and a porcine urethral decellularized matrix...

ABSTRACT For the spiro‐OMeTAD‐based hole‐transporting layer (HTL), despite its widespread implementation, the pragmatic deployment of perovskite solar cells remains profoundly constrained by multifaceted intrinsic ...

Abstract The core pathological mechanisms of diabetic microvascular diseases, such as nephropathy, diabetic retinopathy (DR), and neuropathy, involve the dysfunction and loss of microvascular endothelial cells (ECs), vas...

Abstract Chimeric antigen receptor (CAR) T cell therapies have achieved clinical success in autologous treatment of hematological malignancies. However, their broader application remains limited. Beyond the biological ch...

Food texture is increasingly recognized as a determinant of nutritional safety, metabolic regulation, and overall health. However, conventional approaches to texture modification rely primarily on hydrocolloids, mechanic...

Water build-up has continued to be one of the leading causes of performance variability and loss of durability in proton exchange membrane fuel cells (PEMFCs), especially at the high current density and transient operati...

Abstract Bone defects present significant challenges in clinical practice due to the limitations of traditional treatments. Compared to traditional cell therapies, exosome-based therapies have emerged as a promising alte...

ABSTRACT This work reports an interesting phosphorescent resonance energy transfer (PRET) system with a large Stokes shift (320 nm) and near‐infrared (NIR) delayed fluorescence emission for high‐performance bioimagi...

Abstract Background The ability to guide stem cells toward the bone-forming lineage is a fundamental aspect of regenerative medicine. Conventional protocols for osteogenic differentiation of mesenchymal stem cells typica...

Introduction. Recently, multilevel inverters (MLIs) have been widely investigated for industrial and renewable energy systems as they are valuable in applications where they can produce clean, high-fidelity electrical si...

Abstract This study presents the optimization and performance analysis of a tandem solar cell structure with the solar cell capacitance simulator in one dimension (SCAPS-1D). The novel monolithic two-terminal (2 T) tand...

This paper proposes an innovative model-free deep reinforcement learning-based controller (RL-C) for a grid-connected 5-level packed-U-cell (PUC5) multilevel inverter (MLI). The controller is designed to deliver a high-q...

Porous metallic structures such as Kelvin cells have attracted increasing attention due to their high surface-to-volume ratio and design flexibility, making them promising candidates for lightweight and efficient heat ex...

Abstract Microfluidic platforms have emerged as powerful tools for efficient intracellular delivery of exogenous cargo. While droplet microfluidics coupled with cell mechanoporation shows significant potential, its broad...

ABSTRACT Pyroelectric catalysis has shown promising prospects for sustainable energy generation and medical treatments. However, its potential is limited by intrinsically low pyroelectric coefficients and insufficient in...