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Background The field of extracellular vesicles (EVs) has advanced considerably in recent years with new findings stemming from technical improvements in their isolation and characterization, expanding their potential as ...

Introduction and aims: Human dental pulp stem cells (hDPSCs) play pivotal roles in the regeneration of pulp-dentin complex, yet their odontogenic differentiation is critically modulated by the inflammatory microenvironme...

Glyphosate (GLY) is the most widely used herbicide worldwide. However, in organic and conventional farming systems, a natural alternative — nonanoic (pelargonic) acid (PA) — is gaining importance. PA is a non-selecti...

The complement system is a blood-based immune network that plays a crucial role in fighting infection and maintaining immune homeostasis. The membrane attack complex (MAC) is a pore assembled from complement proteins tha...

Abstract Automobile cabin air filter-deposited particulate matter represents an underappreciated exposure source, yet the differential toxicity between filter sides and underlying mechanisms remain unclear. Here, we syst...

Abstract Man-made synthetic/manufactured nano-objects (MNOs) are increasingly used in almost every scientific sector, including pharmaceutical, agricultural, food, and drug industries worldwide. Rapid advances in nanotec...

Herbal medicines have been extensively used for centuries owing to their therapeutic benefits and comparatively low incidence of adverse effects. Despite their clinical potential, the effectiveness of many herbal formula...

ABSTRACT Cells rely on surface receptors to sense and initiate signalling cascades essential for numerous cellular processes, but engineering of synthetic genetic circuits to sense and rewire receptor activities for user...

Abstract Background Excessive lipid accumulation in the lacrimal glands under diabetic conditions can lead to lacrimal gland dysfunction and reduced tear secretion, subsequently resulting in ocular surface inflammation, ...