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BackgroundTranscriptome−wide association study (TWAS) contributes to discovering novel susceptibility genes related to diseases. Single-cell RNA sequencing (scRNA-seq) has been extensively applied to characterize cellu...

CO₂ emissions are a critical environmental concern driving global climate change, particularly the rise in Earth's average temperatures. Therefore, reducing CO₂ release into the atmosphere is essential. One promising...

Abstract This study presents an integrated numerical and experimental investigation of the aerodynamic performance of the Archimedes Spiral Wind Turbine (ASWT) under wind speeds ranging from 5 to 10 m/s. The analyses wer...

Materias / palabras clave: cfDNA; extraction; quality control; preanalytics; operational verification

The free surface resolution in current load calculations increases costs significantly when using computational fluid dynamics (CFD), even though the small Froude number of a dynamic positioning (DP) vessel suggests mini...

This work presents and validates a direct analytical methodology for the parametric hydrodynamic design of Pelton rotors. The proposed approach combines a one-dimensional theoretical framework for defining global geometr...

Abstract Osteoarthritis is an aging-related systemic disease involving the crosstalk of multiple organs/tissues in metabolism and inflammation, yet little is known about the contribution of liver and marrow adipose tissu...

Circulating cell-free DNA (cfDNA) is valuable for molecular testing, but typically requires specialized collection tubes or immediate processing. We investigated whether residual plasma from heparin separators, routinely...

BackgroundThe methylation status of cell-free DNA (cfDNA) shows promise for the clinical detection of cervical cancer and its precursors; however, its measurement in liquid biopsies is hindered by low cfDNA yields and te...

Abstract Background Circulating cell-free DNA (cfDNA) is a promising biomarker for non-invasive early cancer detection. We integrated methylation entropy, a measure of DNA methylation heterogeneity, with other cfDNA feat...

Widespread attention has been drawn to the underwater biomimetic robotic fish due to its excellent agility and little environmental disturbance. A hybrid-driven bionic robotic fish outfitted with dual-propeller thrusters...

This study investigates two NOx-mitigation strategies, namely exhaust gas recirculation (EGR) and water–diesel emulsification, in a diesel–hydrogen dual-fuel compression ignition engine. A validated three-dimensional...

Prior validation against well-documented benchmark experiments is essential for establishing a reliable computational foundation for liquefied natural gas (LNG) vapor dispersion simulations in safety assessments and haza...

This study explores the aeroelastic behavior of the IEA 15 MW wind turbine rotor during dynamic yaw maneuvers under storm conditions through high-fidelity computational fluid dynamics (CFD) simulations. The focus is on...

Toxic gases released during drilling and blasting operations in underground powerhouse of hydropower stations pose a serious threat to the safety of super-large cavern construction. This study takes the Level Ⅳ main pl...

Underwater radiated noise (URN) from submarine propulsors requires reliable flow prediction as a prerequisite for cavitation and acoustic analyses. This study validates a computational fluid dynamics (CFD) workflow to pr...

The purpose of this study is to justify the design parameters of spiral-vortex equipment ensuring energy-efficient desulfurization of flue gases from autonomous medium-capacity gas-piston power plants (GPPPs). The study ...

Pump-jet propulsors are widely used in marine applications because of their advantages in propulsive efficiency, cavitation performance, and low noise performance. However, the lack of a standard series database still li...

Abstract Effective respiratory therapy relies heavily on inhaler device efficiency and patient technique. While device performance is well-documented in idealized induction ports, there remains a critical lack of data in...

The main objectives of the study are to develop a methodology for calculating the energy efficiency of a pneumatic drive with controlled braking and compressed air recuperation based on a three-dimensional CFD model, as ...

Underwater gas pipelines are vital for energy transportation but are often subjected to harsh environments, and any leakage can have significant environmental consequences. Substantial underestimation of gas plume format...

Unmanned surface vehicles (USVs) operating in open-sea environments experience significant roll motion due to wave-induced excitation. The dynamic roll response depends on various factors, including vessel speed, wave en...

Abstract The multicomponent thermal fluid (MTF) process is a pivotal technology for enhancing heavy oil recovery. However, its injection often triggers particle migration and deposition within reservoirs, leading to perm...