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Renal dysfunction in patients with cirrhosis causes significant morbidity, and clinically appears as acute kidney injury (AKI), chronic renal failure (CRF), and CRF on AKI. The main causes of renal dysfunction are preren...

// was proposed that somatostatin and octreotide can drive the splanchic blood into general circulation by constricting the splanchnic vessels and may ameliorate impaired functions in cirrhotic patients by their inhibito...

Traditional hepatology conceptualizes liver cirrhosis as the linear accumulation of extracellular matrix (ECM). However, the stagnation of fibrosis reversal and the persistent risk of hepatocellular carcinoma (HCC) despi...

Genetic hemochromatosis (GH) and alpha-1 antitrypsin (AAT) deficiency (AATD)  are two autosomal recessive disorders associated with an increased risk for liver injury. Among different AATD and GH genotypes, the M-Malton...

Heba Mohamed Abdallah,1 Iman Shaban Osheba,1 Ahmed Abdallah Salman,2 Nahla K Gaballa,3 Merhan Osama Helmi,1 Amr Ragab Ibrahim,4 Asmaa Said Shahat Atta,1 Mohammed Gaber Saad,5 Sara Mohammed Aboagiza,1 Hanaa Saied Abdel Ha...

Introduction: As the prevalence of metabolic dysfunction–associated steatotic liver disease (MASLD), formerly NAFLD, continues to rise, increasing numbers of patients with hepatic dysfunction are undergoing elective or...

In this study, the importance of urinary N-acetyl β-u glucosaminidase (NAG) as an index of renal injury was assessed inpatients with liver cirrhosis. The study was carried out on 14 cirrhotic patients without primary ...

ABSTRACT Background and Aims Late diagnosis of chronic hepatitis B and C, often identified by the presence of advanced disease such as hepatocellular carcinoma or decompensated cirrhosis at the time of initial hepatitis ...

OBJECTIVE: End-stage kidney disease and advanced cirrhosis are sometimes seen concomitantly. Our purpose was to compare hemodialysis (HD) sessions in critically ill cirrhotic patients from ICU versus stable cirrhotic pat...

Abstract Liver cirrhosis represents a progressive vascular and metabolic disease, which results due to chronic inflammatory injury to the tissues and presents with aberrant tissue regeneration, fibrosis with nodular conf...

Background and aimsLiver sinusoidal endothelial cells (LSECs) have a key role in maintaining organismal homeostasis by scavenging blood-borne molecules and inducing specific immune tolerance to ingested antigens. The sca...

Liver cirrhosis is characterized by an excessive accumulation of extracellular matrix components, including hyaluronan (HA). In addition, cirrhosis is considered a pre-neoplastic disease for hepatocellular carcinoma (HCC...

Abstract Background China bears a high burden of both hepatitis B virus (HBV) infection and type 2 diabetes mellitus (T2DM). T2DM accelerates the progression of liver disease among individuals infected with HBV. This stu...

OBJECTIVE: In our study, we aimed to evaluate the history and awareness of hepatitis in HD patients with viral hepatitis who were followed up at our center and in different provinces. MATERIAL and METHODS: A total of ...

Background: Copper (Cu) is an essential trace metal used as a catalytic cofactor for many enzymes. However, it can have nocive effects when it participates in the Fenton reaction, producing reactive oxygen species (ROS)....

Abstract Background This study was motivated by the high prevalence of anemia of inflammation (AI) in systemic lupus erythematosus (SLE) and the poorly explored potential link between the underlying inflammatory drive an...

Abstract Introduction Glecaprevir/pibrentasvir (G/P) is globally approved for the treatment of chronic hepatitis C virus (HCV) infection and for acute HCV infection in the USA. The efficacy and safety of G/P has been cl...

OBJECTIVE: The aim of the was is to evaluate electrolyte changes and the relationship between electrolytes and glucose regulation in type 2 diabetic patients. MATERIAL and METHODS: Data of diabetic patients aged 30-90...

Yu Zhao,1,* Luting Wang,2,3,* Shengrui Zhu,4 Rui Feng,5 Wei Zhang1 1Geriatric Medicine Center, Department of Endocrinology, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzho...

ABSTRACT Background and Aims To evaluate the transition of Carbohydrate antigen 125 (CA‐125) from an ovarian tumor marker to a versatile indicator of systemic congestion and fluid overload. Methods A literature review ...

Metabolic dysfunction-associated steatohepatitis (MASH) represents a growing global health challenge due to its propensity to progress to irreversible hepatic disorders, including fibrosis, cirrhosis, and carcinoma. This...

Abstract Introduction Hepatitis C virus (HCV) infection is related with several liver diseases such as cirrhosis and hepatocellular carcinomas, leading to more than 0.5 million deaths every year and to a great global bu...

Abstract Minimal hepatic encephalopathy (MHE) is a cognitive, motor, and sleep-related disorder resulting from liver impairment, often linked to elevated ammonia levels. Zinc deficiency is common in patients with cirrhos...