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BackgroundThe association between peripheral blood immune-inflammatory markers and neurological involvement in patients with spinal tuberculosis, and to develop a predictive model for early risk assessment. Spinal tuberc...

Jaume Miranda-Rius,1– 3 Gerard Àlvarez,4 Vanessa Blanc,4 Rubén León,4 Albert Ramírez-Rámiz,1,3 Lluís Brunet-Llobet1– 3 1Department of Odontostomatology, Faculty of Medicine and Health Sciences, University of Ba...

Abstract Background Carbapenem-resistant Citrobacter freundii is increasingly reported and recognized as an opportunistic host of mobile carbapenemase-encoding elements in healthcare-associated settings. However, lineage...

ObjectivesTimely administration of appropriate antimicrobial therapy is critical for sepsis management, yet conventional antimicrobial susceptibility testing (AST) methods typically provide results within 24–48 hours a...

Abstract Background Contemporary data reflecting local pathogens and their antibiograms is necessary to select empirical antimicrobial therapy for equine neonates. Hypothesis/Objectives Describe bacterial isolates associ...

Background: Mycoplasma and Ureaplasma species are understudied opportunistic pathogens that infect humans, animals and plants. These infections are often asymptomatic, which, together with fastidious growth requireme...

BackgroundThe research on human microbiota-associated (HMA) animal models is an important tool for studying the human microbiome and holds great potential for elucidating disease mechanisms and microbe-based therapeutic ...

Introduction: Ventilator Associated Pneumonia (VAP) is a common Healthcare Associated Infection (HAI) in mechanically ventilated patients, leading to increased morbidity, mortality, Intensive Care Unit (ICU) stays, and h...

Extended-spectrum β-lactamases (ESBLs), especially those of the CTX-M family, significantly contribute to antibiotic resistance in Escherichia coli. While CTX-M variants are well-characterized in clinical settings, thei...

Introduction: Ureteral Double J (DJ) stents are commonly used in urology to ensure urinary drainage. However, prolonged indwelling time increases the risk of bacterial colonisation and biofilm formation, which can lead t...

OBJECTIVE: This research was designed as a therapeutic and prognostic study to assess the clinical and bacteriological examination findings of crush syndrome patients admitted to our hospital after the Bingol earthquake....

Foodborne pathogen outbreaks impose a substantial and escalating burden on global public health, food systems, and economies, with the World Health Organization estimating over 600 million illness episodes and 420,000 de...

Abstract Introduction Omadacycline is indicated for the treatment of acute bacterial skin and skin structure infections and community-acquired bacterial pneumonia. With limited real-world data, we report the clinical exp...

Daniele Focosi,1 Massimo Franchini,2 Arturo Casadevall3 1North-Western Tuscany Blood Bank, Pisa University Hospital, Pisa, Italy; 2Department of Transfusion Medicine and Hematology, Carlo Poma Hospital, Mantua, Italy; 3D...

Porcine circovirus-associated disease (PCVAD), caused by pathogenic porcine circovirus type 2 (PCV2), remains one of the most economically devastating diseases in the global swine industry, and the continued emergence an...

IntroductionRespiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infections, while effective therapeutic options remain limited. This study investigated the antiviral efficacy, pharmacokinetics...

IntroductionThe emergence of multidrug-resistant bacteria, particularly vancomycin-resistant enterococci (VRE), represents a critical threat to global public health. Therefore, the development of novel therapeutic strate...

BackgroundThe ESKAPEE pathogens Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, Enterobacter spp. and Escherichia coli are the leading causes of nosoco...

Bordetella bronchiseptica encodes and expresses a flagellar apparatus. In contrast, Bordetella pertussis, the causative agent of whooping cough, has historically been described as a nonmotile and nonflagellated organism....

Abstract Background The emergence of tmexCD-toprJ, a plasmid-mediated resistance-nodulation-division efflux pump gene cluster conferring resistance to tigecycline, poses a critical public health threat. While its prevale...

Antimicrobial resistance (AMR) in Klebsiella pneumoniae, especially the co-occurrence of resistance to aminoglycosides and carbapenems, represents a serious threat to global public health. This study reviews the prevalen...

Abstract Background Antimicrobial resistance (AMR) is a growing threat to public health, especially in low- and middle-income countries. This study aimed to identify multidrug-resistant (MDR) pathogens in clinical sample...

The coevolution of the human diet and gut microbiome has played a pivotal role in shaping metabolic, immune, and epigenetic functions across human history. Dietary transitions from high-fiber ancestral patterns to modern...

ABSTRACT Streptococcus gallolyticus subsp. gallolyticus (SGG) is a bacterial pathogen implicated in bacteremia and endocarditis and is often associated with colon tumors in elderly individuals. The development of colorec...