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Abstract Background Alzheimer’s disease (AD) is a growing global health concern, and emerging evidence suggests that oral health—particularly tooth loss—may be linked to cognitive decline. While implant therapy eff...

Abstract Background Bright Light Therapy is effective in improving sleep and circadian rhythms. However, little is known regarding the effects of BioDynamic Lighting. The current study examined whether BioDynamic Lightin...

Abstract Background Enhanced Group Activity Kits (EGAKs) were developed to maximize the impact of group activities for persons living with dementia while minimizing burden on activity leaders. Previous research has shown...

Exosomes, a specialized class of extracellular vesicles, exhibit significant therapeutic potentials for neurological disorders, in particular for vascular dementia (VaD). VaD is the second most common form of dementia, c...

IntroductionWhile shared activities foster connection between people living with dementia (PLWD) and their care partners, emotional distress and daily caregiving responsibilities often make them difficult to initiate. Th...

BackgroundFrontotemporal dementia is an umbrella term that encompasses several clinical syndromes with impaired behavioral, language, and motor functions. These syndromes show considerable overlap in clinical features an...

IntroductionLate-life difficult-to-treat depression (LL-DTD) and dementia frequently coexist in later life, but it remains unclear whether clinical and sociodemographic characteristics, as well as medication exposure pat...

Abstract Background Older people with dementia are regularly excluded from decision-making processes and their wishes and preferences for care are often not respected. The aim of this study was to analyze whether the use...

Abstract Background Neuropsychiatric symptoms (NPS) are highly prevalent in nursing home residents. The main aims of this study were to examine whether music-based care (MBC) had sustained effects on NPS in nursing home ...

BackgroundDementia is a progressive neurodegenerative condition with 60.2 million cases worldwide. The disease has financial, psychological, and physical health implications for people affected and their carers. There is...

People with dementia (PwD) face cognitive decline, placing added stress on family caregivers. Challenging behaviour, such as agitation, is one of the prominent behaviours exhibited by PwD, and family caregivers are often...

Abstract BackgroundThe aging and caregiving population is becoming increasingly diverse in the United States, leading to a growing need for culturally adapted interventions to address the unique needs of unde...

Abstract Background Primary care is increasingly tasked with early detection, diagnosis, and management of dementia. Despite policy initiatives, education investments, and development of diagnostic and care pathways in A...

Mild cognitive impairment (MCI) and dementias, such as Alzheimer’s disease (AD)-induced dementia and vascular dementia, are major public health burdens. The blood-brain barrier (BBB) disruption, systemic inflammation, ...

Abstract BackgroundLong-term care facilities are increasingly caring for persons living with dementia as this population grows. Frontline care workers provide most hands-on support, yet they often have limite...

Introduction Interaction plays a central role in the delivery of care and in supporting participation and well-being in healthcare. For people living with advanced dementia, cognitive and communicative impairments can re...

Introduction Behavioural and psychological symptoms of dementia (BPSD) affect up to 80% of people with dementia and pose significant challenges in the context of care. Psychosocial interventions have been recommended as ...

Jie Wu,1,* Xuelian Li,1,* Weichu Liu,2 Yingzhuo Ma,1 Qinghua Zhao,1 Mingzhao Xiao,1 Jun Wang1 1Department of Nursing, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s R...

IntroductionAssessing attention and frontal lobe function is essential for diagnosing dementia. The Stroop test is widely used for these purposes, and its validity and reliability have been verified. Nevertheless, test-r...

BackgroundThe landscape of neurological manifestations of HIV remains unknown after HAART is applied. This study aimed to characterize the spectrum of neurological disorders in people with HIV.MethodsThis cross-sectional...

Yueyue Chang,1,2 Xuke Zhang,3 Chuanqing Yu,2 Lei Zhu,1 Shiyu Sun,2 Zhongwu Sun1 1Department of Neurology, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, People’s Republic of China; 2Department of ...

ABSTRACT Background and Aims Hearing and vision impairments are prevalent health conditions among older adults, negatively affecting functional ability, mental and social well‐being, quality of life and increasing the ...

Abstract Background This study evaluates the impact of the SOCAV program on promoting self-direction of individuals with dementia in nursing homes and examines the behavioral changes in care staff when trained and coache...

Abstract Accumulation of amyloid beta 1–42 (Aβ42) peptide in the extracellular space in the brain is a major observation in Alzheimer’s Disease (AD)-related pathology. Astrocytes are known to play pivotal role in cl...