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BackgroundInsomnia is highly prevalent among adolescents. It is associated with various mental and physical disorders and impairments in daytime functioning. Cognitive behavioral therapy for insomnia (CBT-I) is well supp...

Abstract Background Pharmacotherapy and prescribing are core skills for physicians, and all medical graduates must master the basics. From a medical education perspective, it is important to understand factors that help ...

BackgroundThe relationship between digital disability patterns and cognitive function among older adults remains complex. This research investigates how different patterns of digital disability were associated with cogni...

Contemporary artificial intelligence (AI)-based conversational systems present both opportunities and significant risks in mental healthcare. This article examines the case of a 17-year-old adolescent with prior psychiat...

Abstract Background Generative artificial intelligence (AI) chatbots are being increasingly adopted by adolescents to address mental health–related concerns, such as seeking emotional reassurance, clarifying symptoms, ...

There is unequivocal evidence that alpha-synuclein plays a pivotal pathophysiological role in neurodegenerative diseases, and in particular in synucleinopathies. These disorders present with a variable extent of cognitiv...

Hyperactivity of the hypothalamic pituitary adrenal (HPA) axis in patients with major depression is one of the most consistent findings in biological psychiatry. Experimental data support the idea that glucocorticoid-med...

The P2X7 receptor is a member of the P2X family of ligand-gated ion channels. A single-nucleotide polymorphism leading to a glutamine (Gln) by arginine (Arg) substitution at codon 460 of the purinergic P2X7 receptor (P2X...

El presente trabajo releva y analiza ciertos antecedentes históricos de fines del siglo XIX y principios del XX para establecer relaciones entre los saberes “psi” y la denominada “cuestión social” en Chile. Se...

Curcumin (diferuloylmethane), a polyphenolic compound derived from the spice plant Curcuma longa, displays multiple actions on solid tumours including anti-angiogenic effects. Here we have studied in rodent and human pit...

Frontal and parietal regions are associated with some of the most complex cognitive functions,and several frontoparietal resting state networks can be observed in wakefulness. We used functional magnetic resonance imagin...

Poststroke anxiety and depression (PSAD/PSAnx) are common and heterogeneous emotional disorders among stroke survivors, significantly impacting functional recovery, quality of life, and long term prognosis. Their pathoge...

Abstract Neuroimmunological diseases arise from a complex interplay of genetic susceptibility, environmental exposures, and immune-mediated mechanisms. In this context, modifiable lifestyle and environmental factors may ...

Abstract INSPIRE-PNRM+ (short for InterdiSciPlinary and InteRsectoral telemedIcal Evaluation, Coordination and Therapy at the ParkinsonNet RheinMain+) is an one-year, multicentre, interventional, open-label, two-arm, 1:1...

Abstract Objective Medical students are a population at increased risk for anxiety due to their demanding schedule and concerns about potential stigmatization, which often discourage them from seeking help. It has been ...

Abstract Background Chronic subdural hematoma (cSDH) is a prevalent neurological condition with a significant incidence and mortality rate, particularly among elderly individuals. Despite various treatments, the risk of ...

Özge Özen Gökmuharremoğlu,1 Aysel Çoban Taşkın2 1Department of Neurology, Faculty of Medicine, Kastamonu University, Kastamonu, Turkey; 2Department of Neurology, Izmir Tepecik Trainin...

Background Music therapy is a promising complementary intervention for addressing various mental health conditions. Despite evidence of the beneficial effects of music, the acoustic features that make music effective in ...

Abstract Ecological momentary assessment (EMA) is a tool facilitating the repeated collection of real-time data in naturalistic settings that can be applied to clinical research. Despite established methodological streng...

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