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Objective: Anemia is one of the most important factors that decrease the quality of life in patients with end-stage renal desease receiving hemodialysis treatment. In these patients, Erythropoietin stimulating agents (E...

Abstract Background Hypoxia is a key driver of fibrosis and is associated with capillary rarefaction in humans. Objectives Characterize capillary rarefaction in cats with chronic kidney disease (CKD). Animals Archival ki...

In order to describe seasonal changes in Lyme diseases risk rate at three localities in Serbia, during the period of 2003-2005, a total of 1542 Ixodes ricinus ticks (493 nymphs, 525 females and 524 males) were examined. ...

Background and aim: Angina pectoris is a clinical syndrome usually characterized by episodes or paroxysms of pain or pressure in the anterior chest. The cause is insufficient coronary blood flow, resulting in a decreased...

Atopic dermatitis is a frequent, chronic and recurrent inflammatory skin disease with complex etiology. Typical symptoms of this disease are persistent itching and dry skin. To assess the severity of the disease we use v...

Dialysis is used when the patient's kidneys can no longer perform their functions normally; it is a treatment that performs the functions of natural kidneys. Most patients begin dialysis when their kidneys have lost 85-9...

Abstract Background Schistosomiasis is a global health problem affecting 250 million people, with 90% in Sub-Saharan Africa. In Botswana, the burden is high in the Okavango delta because of the water channels. WHO recomm...

Background: Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by memory loss and cognitive decline. One of the leading theories explaining AD pathology is the emergence of cortical hypo...

Abstract The integration of the multitude of ultrasound techniques into a “one-stop” liver clinic model will revolutionize the management of liver diseases. This approach streamlines patient care by providing immedia...

Abstract Background Reticulocyte indices have been suggested as alternatives to transferrin saturation (TSAT) for iron status assessment in humans and dogs but they have not been evaluated thoroughly in cats. Objectives ...

Background Coronary artery disease (CAD) remains a major global health burden with limited precision for early risk assessment and stratification. This study aims to investigate circulating Metastasis-Associated Lung Ade...

Embodied cognition research on Parkinson's disease (PD) points to disruptions of frontostriatal language functions as sensitive targets for clinical assessment. However, no existing approach has been tested for crossling...

Abstract Background Kawasaki disease (KD) represents the leading cause of acquired heart disease in children, with timely diagnosis and treatment being crucial to prevent severe coronary complications. The widespread use...

IntroductionThe long-term efficacy of electroacupuncture (EA) in treating cognitive symptoms of Alzheimer’s disease (AD) remains unclear, and its time-dependent relationship requires further investigation.MethodsSixty-...

Quality of life (Qol) results from a complex interplay of physical, mental, and social aspects. Traditional assessments of Qol may not adequately describe well-being in serious chronic illness such as in people with Park...

Abstract Parkinson’s Disease (PD) is a progressive neurodegenerative disorder that causes motor and cognitive impairments, affecting approximately 1% of individuals over 60 years of age. Speech impairments are among th...

Abstract Background Neuronal intranuclear inclusion disease (NIID) is a rare and progressive neurodegenerative disorder, distinguished by extreme clinical heterogeneity that frequently results in diagnostic delays. Whil...

Abstract Objective To investigate the association between the Systemic Immune-Inflammation Index (SII), Systemic Inflammation Response Index (SIRI), and in-stent restenosis (ISR) following percutaneous coronary intervent...

Abstract To examine the association between cardiometabolic index (CMI), including baseline CMI and cumulative average CMI (CumCMI), and the risk of cardiovascular disease (CVD) among Chinese middle-aged and older adults...

Abstract Objectives To characterize white matter microstructural abnormalities in thyroid eye disease (TED) using tract-based spatial statistics (TBSS) of diffusion tensor imaging (DTI) and diffusion kurtosis imaging (DK...

Abstract Background Sub-Saharan Africa (SSA) has been witnessing a persistent increase in the burden of cardiovascular diseases (CVD), such as stroke and heart disease, over several decades. A key driver of this burden h...

Introduction: Vaccination against foot-and-mouth disease virus is regarded as the most effective way to prevent disease. Selection of appropriate vaccine strains is challenging due to lack of cross-protection between ser...

Galectins, a family of animal lectins, play central roles in immune system regulation, shaping both innate and adaptive responses in physiological and pathological processes. These include rheumatoid arthritis (RA), a ch...

Abstract Background Current understanding of the fluid biomarker profile in early-onset Alzheimer’s disease (EOAD) associated with pathogenic APP variants remains limited. We characterized four EOAD pedigrees carrying ...