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Abstract This study introduces a multiplex high-resolution melting (mHRM) assay for efficient sex identification of Cannabis sativa L. using three MADC markers and nine SCAR markers. This method enables accurate and rapi...

Background and Aim: Cryopreservation of boar semen is widely used for genetic conservation and artificial insemination; however, it induces oxidative stress and molecular alterations that compromise sperm function. Epige...

Post-transplant lymphoproliferative disorders (PTLD) represent a heterogeneous group of complications with rising complexity, particularly as EBV-negative forms are increasingly recognized in adult recipients. While earl...

Abstract Background Lupus retinopathy (LR) is a sight-threatening complication of systemic lupus erythematosus (SLE), yet disease-specific serologic biomarkers are lacking. Previous studies have shown that anti-recoverin...

Abstract Background Breast cancer prognosis is the result of complex interactions between tumor biology, treatment, and host factors. While germline genetic variation is increasingly incorporated into breast cancer risk ...

This study compared the results of molecular genetic analysis using PCR markers (HVM68, 1kb-insertion, HvMATE-21indel) of ten barley (Hordeum vulgare L.) genotypes with a phenotypic evaluation of their aluminum tolerance...

Abstract This study investigates the unconventional effects of gamma irradiation and/or metal-organic frameworks (MOFs) on Raphanus sativus. Silver chromate/aluminum-based MOFs were applied to both irradiated and non-irr...

Abstract Frequent consumption of poor-quality diets “junk food” leads to the accumulation of sugar-derived advanced glycation end-products (AGEs), promoting inflammation and oxidative stress (i.e., diminished endogen...

The article presents the results of the study conducted in 2024 to determine the effect of IGF1 gene polymorphism on the predisposition of cows to ketosis. The objects of the study were first-calving cows of the Kostroma...

The purpose of the review is to analyze the results of scientific research on the effect of antioxidant activity of potatoes on human health, to consider modern approaches to breeding potato with high antioxidant activit...

Abstract Objective Deep vein thrombosis (DVT) represents a major thrombo-inflammatory disorder with substantial diagnostic challenges. Emerging evidence implicates that neutrophil extracellular traps (NETs) and miR-155 a...

Yu Luo,1 Suning Huang,1,2 Haichuan Xie,3 Bei Zhang,3 Fei Ma,1– 4 Yanting Lin,1– 4 Yan Ning,1– 4 Jiaman Wu1– 4 1Graduate School, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510405, People’s R...

Abstract Background Rifampicin-resistant tuberculosis (RR-TB) remains a major challenge for TB control in Malawi, particularly in densely populated districts such as Blantyre. Most rifampicin resistance is caused by muta...

Abstract Objective Intestinal organoids serve as important tools for drug screening, but the extent to which they recapitulate in vivo tissue microenvironments and drug responses remains inadequately evaluated. This s...

ABSTRACT Background Lead is a nonessential, toxic heavy metal that causes widespread environmental contamination, affecting humans, animals, plants, and ecosystems. Globally, an estimated 800 million children have blood ...

Abstract Objective This study aimed to systematically identify and validate KIF15 as a potential diagnostic and prognostic biomarker in colon cancer (CC) using integrated bioinformatics analyses. We further explored its ...

Abstract Background  The genomic and epigenetic landscape of the gasdermin family across cancers, and its clinical relevance, remain incompletely defined.  Methods Multi-omics features of gasdermins across 33 cancer ty...

Abstract Objectives Cerastium davuricum Fisch. ex Spreng. is distributed in European Russia to Mongolia and West Himalaya, and leaves are traditionally used for cooking and drying. Unfortunately, there have not been enou...

Application of modern methods of genetic testing allows to supplement traditional breeding with new ways of predicting economically useful qualities in animals. To improve the parameters of meat productivity in sheep of ...

The IKAROS family of zinc finger transcription factors (IKZF1–4) plays a central role in lymphocyte development and immune regulation. Pathogenic IKZF1 variants produce a wide phenotypic spectrum related to whether the...

Abstract Background Staphylococcus aureus skin infections represent a persistent clinical challenge owing to their high pathogenicity, multidrug resistance, and biofilm-associated recurrence, which collectively impair an...

Abstract Dysfunction of epithelial cell contacts associates with a myriad of human diseases. Cisplatin is an effective antineoplastic agent where it interferes with DNA replication in proliferating cells, but it causes k...

Abstract Prostate cancer (PCa) is a heterogeneous and prevalent neoplasm, traditionally stratified by PSA and Gleason Score. However, these biomarkers have prognostic limitations, driving the search for new molecular mar...