Buscar recursos académicos

Abstract Background Previous studies have evaluated traditional Chinese medicine (TCM) clinical randomized controlled trial (RCT) literature broadly, but they have provided limited depth in evaluating the specific aspect...

Mitochondrial dysfunction is a convergent hallmark of biological aging and a mechanistically attractive target for gerotherapeutic development. Yet translation of mitochondria-focused interventions has been limited by pa...

Abstract BackgroundTripterygium glycoside tablets (TGTs), a traditional Chinese medicine–based therapy and a type of conventional synthetic disease-modifying antirheumatic drug (csDMARD), have shown promise...

Abstract Background Little is known about health-related quality of life (HRQoL) in immunocompromised people during and after COVID-19 illness. We describe HRQoL outcomes from the EPIC-IC trial, which included participan...

Abstract Background In dogs, antiepileptic drugs (AED) cause lethargy but quantitative data regarding the effects of AED on activity levels are not available, and little is known about how AEDs affect sleep quality. Obje...

Abstract Background Hospital indoor air is contaminated with multidrug-resistant bacteria, and this contributes to their spread. However, there is limited information linking environmental and atmospheric factors to the ...

BackgroundMigraine is a common neurological disorder that substantially affects patients’ quality of life. Chinese botanical drug decoctions are used in migraine management; however, the comparative efficacy and safety...

Abstract A selective and eco-friendly spectrophotometric approach was developed for the quantitative determination of entacapone (ENT) in the presence of its co-formulated drugs carbidopa (CAR) and levodopa (LEV) which e...

Shenfu Injection (SFI) is a standardized botanical drug derived from two Chinese medicinal herbs Panax ginseng C.A.Mey. and Aconitum carmichaelii Debeaux. SFI is historically used for “restoring yang and reversing coll...

Abstract Background Malaria continues to pose a major public health challenge in sub-Saharan Africa (SSA), where more than 95% of global cases and deaths occur. Despite WHO Global Technical Strategy for Malaria (GTS) tar...

BackgroundPhysical health is the basic indicator to evaluate the health of drug addicts after the process of drug rehabilitation. In order to better improve the deficiency degree of physical health of drug addicts, it is...

BackgroundNeutrophils, which are polymorphonuclear leukocytes of the phagocytic system, serve as critical mediators of inflammation-induced injury and are implicated in various diseases. However, the role of neutrophils ...

Chemotherapy-induced gastrointestinal dysfunction (CIGD) is a multifactorial clinical syndrome that substantially limits treatment tolerance, continuity, and quality of life in patients with cancer. Although targeted the...

Background: This study developed and systematically optimized an ion-pair hydrophilic interaction liquid chromatography (IP-HILIC) system for oligonucleotide medicine analysis, aiming to the issues of insufficient resolu...

Diabetes mellitus emanates from a dysfunctional metabolic process and it affects human population globally, and causes a decline in the quality of life and increase in mortality rate due to its complications and adverse ...

Introduction and aim: One common therapy for end-stage hallux rigidus symptoms is arthrodesis of the first metatarsophalangeal joint (MTP). Surgery is usually advised for symptomatic patients with arthritis when conserva...

Heart failure (HF) remains a leading cause of morbidity and mortality worldwide, with persistent sterile inflammation emerging as a critical driver of maladaptive cardiac remodeling beyond hemodynamic stress alone. Recen...

More than 76 million people worldwide have alcohol problems, and another 15 million have drug problems. Motivational interviewing (MI) is a psychological treatment that aims to help people cut down or stop using drugs an...

Nonvalvular atrial fibrillation is the most prevalent sustained arrhythmia in chronic kidney disease patients. When compared to warfarin, new oral anticoagulants are found to be non-inferior or superior in safety and eff...

Zhaoyu Zhang,1,2,* Guangyang Chen,1,3,* Kaiyuan Zheng,4,* Meifang Lin,1,2 Dali Zheng,1 Youguang Lu,1,2 Li Huang,1,3 Xiaohang Chen,1,2 Ruihuan Gan1,2 1Fujian Key Laboratory of Oral Diseases, School...

Abstract Background Acute liver failure (ALF) is a life-threatening syndrome characterized by rapid deterioration of liver function, resulting in high mortality and posing a substantial global health burden. Human embryo...

The National Formulary plays a critical role in promoting rational drug use and controlling healthcare costs within Indonesia’s National Health Insurance system. Ensuring compliance with formulary restrictions, includi...

This protocol outlines planned methodology for a systematic review and meta-analysis of dopaminergic neuroimaging findings in individuals with opioid use disorder (OUD). Converging evidence across substance use disorders...

Abstract Background Non-small-cell lung cancer (NSCLC) exhibits pronounced molecular heterogeneity, and current predictive models rarely incorporate mitochondrial quality-control programs such as mitophagy. We hypothesiz...