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A técnica eletrofisiológica Potenciais Relacionados ao Evento (PRE) vem sendo amplamente utilizada para o estudo da atividade cerebral correspondente a processos cognitivos específicos. O presente artigo apresenta uma...

Abstract Multimodal neural interfaces that integrate electrical and optical functionalities are promising tools for neuroscientific and clinical applications that involve recording and manipulating neuronal activity. How...

Drug-induced cardiac arrhythmias are central to physiology and pharmacology education, yet students often struggle to connect electrophysiological mechanisms with dynamic electrocardiographic (ECG) changes. We developed ...

"Electroencephalography (EEG) system validation faces a fundamental challenge: the absence of ground truth when measuring human subjects. Physical head phantoms provide controlled testing environments with known signals;...

Abstract Background Myocardial sleeves of the caudal vena cava are the predilection site for atrial tachycardia (AT) in horses. Caudal vena cava isolation guided by the ablation index, a lesion quality marker incorporati...

Dapagliflozin, a sodium–glucose cotransporter 2 (SGLT2) inhibitor widely used for the treatment of diabetes, has been consistently associated with cardiovascular protection, including attenuation of ischemia/reperfusio...

Abstract High-density, long-term stable decoding of whole-brain function is crucial for advancing basic neuroscience research and developing neural disorder therapies. However, two major challenges remain: the lack of sc...

IntroductionVisual electrophysiology, including electroretinograms (ERG) and visual evoked potentials (VEP), provides a real-time functional assessment of retinal and post-retinal pathways, complementing structural imagi...

Abstract TRPV5 channels play a critical role in calcium homeostasis and are implicated in various pathophysiological conditions. Here, we demonstrate that the monoterpene menthol, commonly used for pain and inflammation ...

INTRODUCTION: Generalised anxiety disorder (GAD) is primarily characterized by persistent anxiety and worry, factors which are potentially associated with alterations in P-wave parameters. This study aimed to investigate...

TRPM2 is a calcium-permeable cation channel that functions as an oxidative stress sensor and plays a key role in various pathologies, particularly ischemic stroke. The activation of hsTRPM2 requires cooperative engagemen...

Abstract Background Migraine with aura is clinically linked to cognitive impairment, yet sex differences and underlying mechanisms are unclear. Cortical spreading depression (CSD) is widely regarded as the electrophysiol...