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Background: The health of the population is shaped by political, social and environmental conditions – referred to as contextual factors in this paper – which influence the risk of type 2 diabetes and other non-commu...

ABSTRACT This study aims to analyze the effects of multimodal environmental modification (MEMO) of cats with recurrence of lower urinary tract signs (LUTS). Treatment of FLUTD included pharmacological treatment, dietary ...

Psoriasis is a chronic inflammatory skin disease associated with increased proliferation of the epidermis. Combination of genetic, immunological and environmental factors underlies the skin lesion. Until recently, psoria...

Copper is an essential trace element in the human body, extensively involved in key physiological and biochemical processes such as antioxidant defense, energy metabolism, neural signaling, and immune regulation. In rece...

Vitiligo is a quite frequently occurring skin disease. Although it does not cause any pain or internal organ damage, it constitutes a significant cosmetic problem having a significant impact on quality of life. A number ...

Abstract Autoimmune diseases (AIDs) result from intricate interactions among genetic, environmental and immune factors, with emerging evidence underscoring the role of the central nervous system (CNS) in their pathogenes...

This integrative review synthesizes current knowledge on the physiological responses and adaptive mechanisms of amphibians and reptiles to multiple interacting environmental stressors, with particular emphasis on synergi...

Background: Metal-associated free fatty acids (FFAs) on cardiometabolic diseases have rarely been studied. Objective: To investigate metallomics-FFAs relationship, and identify FFAs as potential mediators linking metals ...

Abstract Objective: To examine and synthesize data on the environmental impact of diet in Latin America. Design: A systematic review was conducted in April 2024, using Medline, Embase, Web of Science and Scopus databa...

Longitudinal profiling of 136 newborns shows thymic output peaks at 3–4 mo, correlating with plasma RANKL, lymphotoxin-α, and the TCRD variant rs2204985. In thymic tissue, RANKL tracks medullary—but not cortical—e...

Clinical and subclinical Shigella infections among children living in low- and middle-income countries (LMICs) have been associated with long-term adverse effects such as impaired linear growth. The mechanism for the imp...

Transposable elements (TEs) make up almost half of the human genome and are among its most densely methylated regions. Their epigenetic silencing is crucial for genomic stability and immune homeostasis, and accumulating ...

Aerosol contamination of an aircraft cabin by infectious passengers is a concern of passengers, aircrew and the aviation industry. This may be especially important during a pandemic, such as COVID-19, where the full exte...

The interest in aerosol contamination of aircraft passenger cabins has increased since the onset of the COVID-19 pandemic. Mathematical models have been developed to help describe how an aerosol behaves in a closed space...

Background and Aim: Ticks and tick-borne diseases (TBD) continue to pose a significant threat to livestock production and rural livelihoods in sub-Saharan Africa (SSA). The control of ticks has relied predominantly on th...

Background: Infectious diseases are a global problem, the second human cause of death. Infectious diseases caused by pathogenic bacteria have been treated with a high degree of efficacy. However, even when the 20th centu...

The lung, and more specifically the airway epithelium, is continuously exposed to a wide range of inhaled environmental agents. Acting as a frontline physical and biochemical barrier, the airway epithelium orchestrates e...

Soybeans hold a deep cultural significance with its origin in Asia. All of the current modern cultivars belong to the same Glycine max (L.) Merrill, which can be distinguished primarily by their seed coat pigmentation. T...

The global burden of chronic kidney disease (CKD) is rapidly increasing with a projection of becoming the 5th most common cause of years of life lost globally by 2040. Aggravatingly, CKD is a major cause of catastrophic ...

Parabens, ubiquitous preservatives with endocrine-disrupting potential, may adversely affect mental and cardiometabolic health, but evidence in elderly populations is limited. This study aimed to explore the relationship...

Recently, agricultural productivity and food security have been seriously threatened by climate changes, which has increased poverty globally. So, it is necessary to address these changes and minimize their detrimental i...

Incense and candles are commonly utilized for relaxation, deodorization, aesthetics, and religious observance. Both are used ubiquitously and viewed innocuously. However, both modalities release a multitude of compounds,...

Abstract Background The present goal of the World Health Organization (WHO) 2021–2030 roadmap for Neglected Tropical Diseases is to eliminate schistosomiasis as a public health problem, and reduce its prevalence of hea...

Abstract BackgroundHealth and health care systems are progressively challenged by more frequent natural and human-caused hazards. A hazard becomes a disaster when vulnerability and exposure interact in comple...