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Dual-energy and perfusion CT for predicting response to chemo-radiotherapy in head and neck cancer: an exploratory study
Artículo
Material complementario disponible Artículo DOAJ
Dual-energy and perfusion CT for predicting response to chemo-radiotherapy in head and neck cancer: an exploratory study
Benjamin Van Honacker et al · Frontiers Media S.A · 2026 · ISSN 2234-943X
IntroductionHead and neck cancer (HNC) is a major global health issue, often linked to smoking, alcohol, and viruses (HPV, EBV). HPV-driven oropharyngeal squamous cell carcinoma (OPSCC) showed distinct biology and better...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Kynurenine promotes angiogenesis through mTOR signaling in head and neck squamous cell carcinoma
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Kynurenine promotes angiogenesis through mTOR signaling in head and neck squamous cell carcinoma
Shuoqi Lin et al · Nature Portfolio · 2026 · ISSN 2045-2322
Abstract Angiogenesis and its maturation play a crucial role in the progression and prognosis of head and neck squamous cell carcinoma (HNSCC). Tumor growth relies on an adequate blood supply to meet metabolic demands, w...
LCC LCC:Medicine; TENDOlNjaWVuY2U~Idioma eng
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Personalizing the treatment of head and neck cancer in vitro: The 3D-OTC model
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Personalizing the treatment of head and neck cancer in vitro: The 3D-OTC model
Fabian Stögbauer et al · BMC · 2026 · ISSN 1741-7015
Abstract Background Treatment of head and neck squamous cell carcinoma (HNSCC) remains challenging and the survival rates of affected patients remain poor. A three-dimensional organotypic co-culture (3D-OTC) model where ...
LCC LCC:MedicineIdioma eng
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Precision immunotherapy for head and neck cancer: therapeutic combinations, biomarker strategies, and translational challenges
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Precision immunotherapy for head and neck cancer: therapeutic combinations, biomarker strategies, and translational challenges
Kohei Okuyama et al · BMC · 2026 · ISSN 1476-4598
Abstract Immune checkpoint inhibitors (ICIs) have fundamentally altered the therapeutic paradigm for head and neck squamous cell carcinoma (HNSCC); however, durable clinical benefit remains limited to biologically define...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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The effect of quantitative goal exercise combined with whole process refined nutrition management on the nutritional status and quality of life of head and neck cancer patients undergoing radiotherapy: an open-label, randomized, controlled trial
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The effect of quantitative goal exercise combined with whole process refined nutrition management on the nutritional status and quality of life of head and neck cancer patients undergoing radiotherapy: an open-label, randomized, controlled trial
Juanli Shi et al · BMC · 2026 · ISSN 1748-717X
Abstract Objective To explore the clinical effect of a combined intervention comprising Quantitative Goal Exercise (QGE) and Whole-Process Refined Nutrition Management (WP-RNM) on patients with head and neck cancer under...
LCC TENDOk1lZGljYWwgcGh5c2ljcy4gTWVkaWNhbCByYWRpb2xvZ3kuIE51Y2xlYXIgbWVkaWNpbmU~; TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neSIdioma eng
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The influence of brachytherapy on tooth development: a longitudinal study of pediatric head and neck tumor survivors
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The influence of brachytherapy on tooth development: a longitudinal study of pediatric head and neck tumor survivors
Guohao Zhang et al · BMC · 2026 · ISSN 1472-6831
Abstract Background Interstitial brachytherapy is an effective and organ-preserving radiotherapeutic modality for pediatric and adolescent patients with head and neck tumors, offering favorable outcomes with minimal impa...
LCC TENDOkRlbnRpc3RyeQ~~Idioma eng
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USP33 as a potential prognostic and immunological biomarker in head and neck squamous cell carcinoma: a TCGA-based bioinformatic analysis
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USP33 as a potential prognostic and immunological biomarker in head and neck squamous cell carcinoma: a TCGA-based bioinformatic analysis
Namira Fateen et al · SpringerOpen · 2026 · ISSN 2090-2441
Abstract Background Head and neck squamous cell carcinoma (HNSCC) is a prevalent and aggressive malignancy with limited prognostic markers. Ubiquitin-specific peptidase 33 (USP33) has emerged as a potential modulator of ...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~; LCC:GeneticsIdioma eng
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[18F]FDG PET/CT multiomics identifies Hedgehog-driven HPV-negative head and neck squamous cell carcinoma
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[18F]FDG PET/CT multiomics identifies Hedgehog-driven HPV-negative head and neck squamous cell carcinoma
Stefan Stoiber et al · BMC · 2026 · ISSN 1476-4598
Abstract Head and neck squamous cell carcinoma (HNSCC) is a highly heterogeneous malignancy with limited predictive markers to guide personalized treatment, particularly in human papillomavirus (HPV)-negative cases, whic...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Fuzzy masks: boosting radiomic reliability in head and neck tumors amid delineation uncertainty
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Fuzzy masks: boosting radiomic reliability in head and neck tumors amid delineation uncertainty
Jin Cao et al · Elsevier · 2026 · ISSN 2405-6316
Background and purpose: The clinical utility of radiomics in head-and-neck (H&N) cancer is hindered by poor reliability caused by delineation uncertainties from the use of binary mask (BinMask). This study introduced a f...
LCC TENDOk1lZGljYWwgcGh5c2ljcy4gTWVkaWNhbCByYWRpb2xvZ3kuIE51Y2xlYXIgbWVkaWNpbmU~; TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neSIdioma eng
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Impact of reduced robustness settings on the necessity for proton therapy treatment plan adaptation in head-and-neck cancer patients
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Impact of reduced robustness settings on the necessity for proton therapy treatment plan adaptation in head-and-neck cancer patients
Brian Zapien-Campos et al · Elsevier · 2026 · ISSN 2405-6316
Background and purpose: Robust optimization mitigates the effects of range and setup uncertainties in intensity–modulated proton therapy (IMPT) through robustness settings. However, it increases the dose to organs-at-r...
LCC TENDOk1lZGljYWwgcGh5c2ljcy4gTWVkaWNhbCByYWRpb2xvZ3kuIE51Y2xlYXIgbWVkaWNpbmU~; TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neSIdioma eng
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De-escalation of adjuvant radio(chemo)therapy for patients with HPV-positive head and neck squamous cell carcinoma: study protocol for a phase I trial to reduce late toxicity (DELPHI)
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De-escalation of adjuvant radio(chemo)therapy for patients with HPV-positive head and neck squamous cell carcinoma: study protocol for a phase I trial to reduce late toxicity (DELPHI)
Annett Linge et al · BMC · 2026 · ISSN 1471-2407
Abstract Background Patients with locally advanced head and neck squamous cell carcinoma are receiving adjuvant radio(chemo)therapy as standard of care, according to national guidelines. However, patients with human papi...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Evaluation of Candida Species Colonization and Fungal Susceptibility Profile in the Oropharyngeal Mucosa of Patients Receiving Head and Neck Radiotherapy
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Evaluation of Candida Species Colonization and Fungal Susceptibility Profile in the Oropharyngeal Mucosa of Patients Receiving Head and Neck Radiotherapy
Arezoo Aghakouchakzadeh et al · Wiley · 2026 · ISSN 1537-744X
Oral candidiasis is the most common opportunistic fungal infection in patients undergoing head and neck radiotherapy (RT). The present study is aimed at provide the best treatment for patients undergoing RT by determinin...
LCC TENDOlRlY2hub2xvZ3k~; LCC:Medicine; TENDOlNjaWVuY2U~Idioma eng
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Expression of Programmed Death Ligand-1 in Head and Neck Squamous Cell Carcinoma: A Cross-sectional Study
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Expression of Programmed Death Ligand-1 in Head and Neck Squamous Cell Carcinoma: A Cross-sectional Study
Shivani Bhargava et al · JCDR Research and Publications Private Limited · 2026 · ISSN 2249-782X
Introduction: Head and Neck Squamous Cell Carcinoma (HNSCC) is among the most prevalent malignancies worldwide, with poor survival outcomes despite advances in multimodal therapy. Tumour immune evasion through the Progra...
LCC LCC:MedicineIdioma eng
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Integrating transcriptomic data and artificial intelligence to personalize curative treatments for head and neck cancer patients
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Integrating transcriptomic data and artificial intelligence to personalize curative treatments for head and neck cancer patients
Stefano Cavalieri et al · Nature Portfolio · 2026 · ISSN 2397-768X
Abstract Personalized treatment in head and neck cancer remains limited despite substantial biological heterogeneity. Using the SuPerTreat project as a case study, we outline a prototype clinical decision support system ...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Photobiomodulation in Treatment of Head and Neck Cancer-Related Chronic Lymphedema: A Pilot Randomized Controlled Trial
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Photobiomodulation in Treatment of Head and Neck Cancer-Related Chronic Lymphedema: A Pilot Randomized Controlled Trial
Jie Deng PhD, RN, OCN, FAAN et al · SAGE Publishing · 2026 · ISSN 1552-695X
Background: Chronic lymphedema is a common late effect after completion of head and neck cancer (HNC) treatment, contributing to substantial symptom burden and negatively impacting quality of life. No effective approache...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Oral mucositis severity in patient with head and neck cancer undergoing chemotherapy and/or radiotherapy
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Oral mucositis severity in patient with head and neck cancer undergoing chemotherapy and/or radiotherapy
Dewi Oktafia Traktama et al · faculty of dentistry universitas gadjah mada · 2018 · ISSN 2460-0164
Oral mucositis is an inflammatory process and ulcerative of the oral mucosa due to chemotherapy and/or radiotherapy. The incidence and severity of oral mucositis might be influenced by a variety of risk factors, related ...
LCC TENDOkRlbnRpc3RyeQ~~Idioma eng
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Intra- and inter-rater reliability of goniometric head posture measurement in patients with neck pain and hamstring tightness
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Intra- and inter-rater reliability of goniometric head posture measurement in patients with neck pain and hamstring tightness
Aftab Ahmed Mirza Baig et al · BMC · 2026 · ISSN 1471-2474
Abstract Background Neck pain (NP) is a common disabling condition, often associated with forward head posture (FHP) and hamstring tightness. There is limitation in evidence regarding the intrarater and interrater reliab...
LCC LCC:Diseases of the musculoskeletal systemIdioma eng
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Development and external validation of a musculoskeletal ultrasound-based prediction model for limited shoulder range of motion in nursing staff with neck–shoulder pain: a cross-sectional study
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Development and external validation of a musculoskeletal ultrasound-based prediction model for limited shoulder range of motion in nursing staff with neck–shoulder pain: a cross-sectional study
Rui Zhao et al · Frontiers Media S.A · 2026 · ISSN 2296-2565
BackgroundNurses with neck–shoulder pain are at high risk of developing limited shoulder range of motion (ROM), but early prediction tools are lacking. This study aimed to identify risk factors using clinical data and ...
LCC LCC:Public aspects of medicineIdioma eng
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Pain beyond the head: clinical implications of body pain in migraine and tension-type headache in a population-based study
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Pain beyond the head: clinical implications of body pain in migraine and tension-type headache in a population-based study
Woo-Seok Ha et al · BMC · 2026 · ISSN 1129-2377
Abstract Background Body pain significantly affects the quality of life. However, the relationship between headache and pain across broad body regions remains unclear. This population-based cross-sectional study aimed to...
LCC LCC:MedicineIdioma eng
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Craniocervical instability after inadvertent neck hyperextension in Ehlers-Danlos syndrome: a retrospective case series and literature review
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Craniocervical instability after inadvertent neck hyperextension in Ehlers-Danlos syndrome: a retrospective case series and literature review
Chanbin Lee et al · BMC · 2026 · ISSN 1471-2377
Abstract Background Patients with hypermobile Ehlers-Danlos Syndrome (hEDS) are at risk of developing craniocervical instability (CCI). Iatrogenic causes of CCI in hEDS are underreported. We describe a case series of hED...
LCC LCC:Neurology. Diseases of the nervous systemIdioma eng
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The inhibition of the MRN complex by Mirin radiosensitizes particularly HPV-negative HNSCC cell lines
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The inhibition of the MRN complex by Mirin radiosensitizes particularly HPV-negative HNSCC cell lines
Laura S. Hildebrand et al · BMC · 2026 · ISSN 1475-2867
Abstract Background Head and neck squamous cell carcinoma (HNSCC) is a relevant cancer entity with two main risk factors. Human papilloma virus (HPV)-positive ones are induced by virus infection and generally have a good...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~; LCC:CytologyIdioma eng
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Effect of the Size and Shape of Dendronized Iron Oxide Nanoparticles Bearing a Targeting Ligand on MRI, Magnetic Hyperthermia, and Photothermia Properties—From Suspension to In Vitro Studies
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Effect of the Size and Shape of Dendronized Iron Oxide Nanoparticles Bearing a Targeting Ligand on MRI, Magnetic Hyperthermia, and Photothermia Properties—From Suspension to In Vitro Studies
Freis, Barbara et al · Multidisciplinary Digital Publishing Institute · 2023 · ISSN 1999-4923
Functionalized iron oxide nanoparticles (IONPs) are increasingly being designed as a theranostic nanoplatform combining specific targeting, diagnosis by magnetic resonance imaging (MRI), and multimodal therapy by hyperth...
Idioma eng
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Evaluating Baricitinib for Severe Paediatric Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) with Single-Cell Sequencing
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Evaluating Baricitinib for Severe Paediatric Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) with Single-Cell Sequencing
Yang D et al · Dove Medical Press · 2026 · ISSN 1178-7031
Danyang Yang,1 Xin Liu,1 Wenwen Jing,1 Xu Feng,1 Canying Lai,1 Chenyue Liu,2 Zhigang Xu,1,3 Yangang Zhang,1 Jiayi Han,1 Songmei Geng,1 Ruilian Li,1 Dan Li,4 Boyi Cheng,1 Yufei Wu,1 Zhuokun Liu,1 Jialin Lian,1 Zhenghui Wa...
LCC TENDOlBhdGhvbG9neQ~~; LCC:Therapeutics. PharmacologyIdioma eng
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Kandidiasis di Mulut akibat Khemoterapi dan Penatalaksanaannya
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Kandidiasis di Mulut akibat Khemoterapi dan Penatalaksanaannya
Sri Budiarti Wonso Hardjono et al · faculty of dentistry universitas gadjah mada · 2016 · ISSN 2460-0164
Latar belakang: kandidiasis (kandidosis) adalah infeksi jamur yang disebabkan oleh spesies Candida biasanya Candida albicans. Faktor predisposisi yang memicu kandidiasis adalah terganggunya ekologi mulut karena antara la...
LCC TENDOkRlbnRpc3RyeQ~~Idioma eng
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