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Subcapsular hepatic hematoma with hepatic rupture in the postpartum period is a rare but potentially fatal condition, most commonly associated with hypertensive disorders of pregnancy and HELLP syndrome. In women without...

Hepatic manifestations of type 2 diabetes, including steatosis, represent a major complication driven by hepatic lipotoxicity and ceramide accumulation, yet few targeted interventions are available. This study investigat...

Pregnancy is accompanied by complex physiological adaptations that influence hepatic metabolism, bile transport, coagulation, and immune tolerance, which may precipitate the development of pregnancy-specific liver disord...

Abstract Background Therapeutic Communities (TCs) are long-term residential treatment settings for individuals with substance use disorders, who often present with neuropsychological impairments. These impairments may in...

Metabolic dysfunction-associated steatohepatitis (MASH) represents a growing global health challenge due to its propensity to progress to irreversible hepatic disorders, including fibrosis, cirrhosis, and carcinoma. This...

Background: Hepatic metabolic disorders are closely associated with obesity and are characterized by systemic inflammation and liver injury. Moringa oleifera fruit contains various bioactive compounds with potential anti...

ABSTRACT Background Substance use, particularly cannabis and alcohol consumption, presents a growing public health challenge in Ghana, with significant implications for both mental and physical health. While the adverse ...

Hemophilia B is an X-linked recessive bleeding disorder caused by deficiency or dysfunction of factor IX. It typically presents with spontaneous or trauma-induced bleeding, hemarthrosis, and soft tissue hematomas. We rep...

We present the case of a 43-year-old male who presented to pulmonology with 3 years of chronic cough and recurrent sinopulmonary infections. He was diagnosed with bronchiectasis and found to have mild thrombocytopenia an...

Aim: Chronic liver disease (CLD) is characterized by progressive impairment of hepatic function and frequent lipid metabolism abnormalities, with reductions in high-density lipoprotein cholesterol (HDL-C) and other lipop...

Abstract Perinatal failure in the growth hormone (GH)-insulin-like growth factor-1 (IGF-1) axis causes impaired body growth and central and autonomous neurodevelopmental disorders. However, whether a primary neurodevelop...

Abstract The liver is a central organ controlling lipid and cholesterol metabolism and plays a key role in regulating lipoprotein profiles and cardiovascular disease risk. Males and females show clear differences in chol...

Janus kinase (JAK) inhibitors represent a major advancement in the management of immune-mediated inflammatory diseases. A balanced approach that carefully weighs therapeutic benefits against potential risks is essential....

Abstract Introduction No-reflow phenomenon (NRP) after primary PCI in STEMI is strongly linked to early mortality and adverse events. Conventional indices such as the systemic immune-inflammation index (SII), the CRP to ...