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ABSTRACT Bone injuries, particularly those associated with an aging global population, pose a persistent and complex clinical challenge. Current gold‐standard treatments such as autografts, allografts, and metal implan...

Abstract Curcumin, a natural polyphenol with multifaceted anticancer properties, faces significant clinical translation challenges due to poor solubility, rapid metabolism, and low bioavailability. Hydrogels, as biocompa...

This study investigates the complementary modulation of chitosan/keratin hydrogels through the combined use of hexamethylene diisocyanate (HDI) and Pluronic F-68, aiming to tailor mechanical stability, porosity, and biol...

Abstract Bone defects present significant challenges in clinical practice due to the limitations of traditional treatments. Compared to traditional cell therapies, exosome-based therapies have emerged as a promising alte...

Acne vulgaris is a common inflammatory skin condition that affects up to 85% of adolescents and is primarily driven by Cutibacterium acnes (anaerobic bacteria, formerly Propionibacterium acnes). With the rise of antibiot...

ABSTRACT Microorganism‐based therapies, particularly those utilizing probiotics, have emerged as a powerful biomedical strategy owing to their inherent living functionalities. These living systems can dynamically inter...

3D printing has emerged as vanguard technique of biofabrication to assemble cells, biomaterials and biomolecules in a spatially controlled manner to reproduce native tissues. In this work, gelatin methacrylate (GelMA)/al...

Abstract This study developed an antimicrobial hydrogel to control Listeria monocytogenes in Yukhoe (Korean beef tartare). Four hydrogels (hydrogel 1: 5% alginate+1% chitosan+0.2% CaCl2, hydrogel 2: 1% κ-carrageenan+1% ...

The precise treatment and dynamic management of traumatic brain injury pose a substantial challenge to the global healthcare sector. This challenge arises not only from the complex and dynamically evolving pathological m...

Abstract Background To compare the antibacterial activity of conventional intracanal medicaments used in regenerative endodontic treatment (TAP, DAP, Ca(OH)₂, CHX gel) with novel hydrogel-based formulations (chitosan, ...

Subretinal delivery of retinal pigment epithelium (RPE) cells is an important treatment for retinal degeneration patients, and the cell suspension method is the most common approach. Injectable hydrogel-mediated cell eng...

The aim of this work was to synthesize and to characterize new pH-sensitive hydrogels that can be used in the controlled release of drugs, useful for dermal treatments or ophthalmology's therapies. Copolymers containing ...

The aim of this study was to develop topical hydrogels containing diclofenac potassium (DP) at 1 % w/v concentration using conventional hydrophilic hydroxypropyl methyl cellulose (HPMC, 50cPs) and modified hydrophobic ...

BackgroundChronic wounds remain a significant challenge in healthcare due to persistent inflammation and disrupted macrophage polarization.ObjectiveIn this study, we conducted a quantitative comparative analysis to asses...

Natural hydrogels are widely used for 3D-bioprinting because of their qualities fortissue engineering. Recently, hydrogels have been combined with bioactive glasses,due to their angiogenic properties that aid tissue rege...

Objective: The aim of present research work was focus on preparation of PVA/SA hydrogels for Metoclopramide HCl drug release and investigates swelling and release study. Method: Chemical cross-linking method was used for...

Herein we report a facile method for the preparation of hierarchical silica nanostructures through a biomimetic approach. Toward this goal, a protein-directed approach has been proposed to template silica into 3D archite...

The recent development of light-based 3D printing technologies has marked a turning point in additive manufacturing. Through photopolymerization, liquid resins can be solidified into complex objects. Usually, the polymer...

The complex etiology and short-term positive effects of treatments for osteoarthritis (OA) remain a significant challenge globally. The lack of approved disease-modifying OA drugs (DMOADs) and the rapid clearance of intr...

Abstract Per- and polyfluoroalkyl substances (PFAS) and microplastics (MPs) are certain types of persistent plastic contaminants that are a cause of concern to both the ecosystems and human health. The nanotechnologies o...

Soft robotics is a rapidly evolving field that leverages compliant and deformable materials to create robotic systems capable of safe human interaction, environmental adaptability, and bio-inspired motion. Unlike rigid r...

ABSTRACT Spinal cord injury (SCI), which is a severe complication of spinal fractures, often causes the dysfunction of the spinal cord and results in sensory and motor abnormalities. Current clinical treatments—includi...

Synthesis of antibacterial nanocomposite obtained by in-situ photoreduction of Ag+ ions impregnated inside a biocompatible hydrogel matrix is described. Hydrogel matrixes based on N-isopropylacrylamide (PNIPAM) and copol...