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Human induced pluripotent stem cells (iPSCs) are transforming adoptive cell therapy by combining unlimited self-renewal, broad differentiation potential, and high amenability to genome engineering. These attributes make ...

OBJETIVO: comparar a efetividade de baixas doses de misoprostol vaginal (12,5 versus 25 mcg) para indução do trabalho de parto. MÉTODOS: ensaio clínico controlado, randomizado, duplo-cego, realizado entre maio de 200...

Abstract Purpose To evaluate blood loss during misoprostol-induced vaginal births and during cesarean sections after attempted misoprostol induction. Methods We conducted a prospective observational study in 101 preg...

Acute renal impairment due to rhabdomyolysis in patients with hypothyroidism is quite rare. We describe a case of acute kidney injury due to hypothyroidism-induced rhabdomyolysis in a 47-year-old man who was under levoth...

Aims Deleterious effects of metabolic syndrome (MS) on bone are still controversial. In this study we evaluated the effects of a fructose-induced MS, and/or an oral treatment with metformin on the osteogenic potential of...

Combined electric- and magnetic-field control of magnetization orientation and reversal is studied using anomalous Hall effect in an ultrathin ferromagnetic (Ga,Mn)As/(Ga,Mn)(As,P) bilayer. Its anisotropy results from th...

Recent studies from our laboratory provided evidence that part of the carcinogenic effects of ethanol consumption might be related to its in situ metabolism at cytosolic and microsomal levels, to the mutagen acetaldehyde...

Endocrine disruptors (EDs) are exogenous substances or xenoestrogens natural or synthetic, capable of interacting with different systems and altering their normal hormonal regulation, being the reproductive system one of...

"A solar photo-Fenton-like (SPF-like) process is explored for the removal of 1 mg L−1 glyphosate and its main degradation by-product, aminomethylphosphonic acid (AMPA), from Milli-Q water by means of low Fe(III) concen...

Avaliou-se a eficiência da infusão intravenosa de heparina sódica (100UI/kg/8h, a partir de 24h após o fornecimento de carboidrato, até completar 48h) no controle da laminite eqüina experimentalmente induzida por s...

Introduction: This pilot study investigated the effects of ovariectomy-induced estrogen deficiency on the biomechanical properties of intact anterior cruciate ligaments (ACLs) in a porcine model, a biological condition t...

Background: Tuberculosis (TB) remains a global public health challenge, with Thailand identified as a high-burden country for TB and TB-HIV infections by WHO in 2021–2025. While the standard TB treatment regimen—incl...

Abstract Background A frequent electrolyte imbalance, hypocalcaemia can cause anything from asymptomatic symptoms to potentially fatal neuromuscular and cardiac symptoms. Tetany, carpopedal spasm, and ECG abnormalities s...

Abstract Tirzepatide,a dual GLP-1 and GIP receptor agonist, is increasingly used for weight management in both patients with diabetes and patients without diabetes. While gastrointestinal side effects such as nausea are ...

Hypercholesterolemia is a cardinal driver of atherosclerotic cardiovascular disease (ASCVD), one of the major global mortality causes. Associated oxidative stress and lipid peroxidation perturbes HDL-associated paraoxona...

OBJETIVO: comparar parto e seguimento de gravidez entre grávidas adolescentes e não-adolescentes que pariram num hospital terciário da região de Lisboa (Portugal). MÉTODOS: estudo retrospectivo com 10.656 partos. Fo...

OBJETIVO: comparar a acurácia da mensuração ultrassonográfica transvaginal do colo uterino com o escore de Bishop para predição do parto vaginal após indução do trabalho de parto com misoprostol a 25 mcg. MÉTOD...

Abstract Objective To obtain cesarean-section (CS) rates according to the Robson Group Classification in five different regions of Brazil. Methods A descriptive epidemiological study using data from secondary birth r...

Drug discovery research faces significant challenges, with around 90 % of candidate drugs failing in clinical trials. Traditional animal models do not always accurately reflect human physiology and pathology, leading to ...

Abstract Synchronous reluctance motors (SynRMs) are increasingly critical in industrial and traction applications due to their high efficiency, magnet-free construction, and thermal robustness. However, fault diagnosis f...

A non-boundary conforming formulation for simulating complex flows with moving solid boundaries on fixed Cartesian grids is proposed. The direct forcing immersed boundary method (IBM) is implemented in a direct numerical...

The aim of the present work was to determine the in vitro effect of Mentha piperita and Mentha pulegium essential oils against Echinococcus granulosus and to compare the effectiveness of both oils according to the exposu...

Plants are sophisticated and intelligent natural construction materials. They can be used for enhancing the stability of shallow soil slopes and minimizing surface erosion. It is evident that the use of plants can be low...

Shallow lakes are hotspots for carbon processing and important natural sources of methane (CH4)emission. Ebullitive CH4 flux may constitute the overwhelming majority of total CH4 flux, but theepisodic nature of ebullitio...