Buscar recursos académicos

Lung diseases such as pneumonia, tuberculosis, COVID-19, and lung cancer remain significant global health challenges that demand rapid and accurate diagnosis to improve patient outcomes. This study proposes NASNet-ViT, a...

The lung, and more specifically the airway epithelium, is continuously exposed to a wide range of inhaled environmental agents. Acting as a frontline physical and biochemical barrier, the airway epithelium orchestrates e...

Ultrasound-guided percutaneous lung needle biopsy (US-PLNB) is a pivotal diagnostic technique for subpleural pulmonary lesions, offering significant advantages such as real-time imaging, absence of ionizing radiation, an...

Background: Copper (Cu) is an essential trace metal used as a catalytic cofactor for many enzymes. However, it can have nocive effects when it participates in the Fenton reaction, producing reactive oxygen species (ROS)....

ABSTRACT Background and Aims Heparin‐binding protein (HBP) has the potential clinical utility in the early diagnosis and prognosis evaluation of infectious diseases. We aimed to assess the early diagnostic value of HBP...

Lung fibrosis is a severe disease with limited therapeutic options. The vascular niche is critical for lung function and fibrotic diseases, but the mechanisms by which endothelial cells (ECs) are regulated during lung in...

Lung cancer is one of the most frequently diagnosed cancers and the leading cause of cancer-related death worldwide. Hypoxia and histone lactylation are emerging regulators of tumor progression and immune escape. However...

Abstract Background Pediatric connective tissue disease-associated interstitial lung disease (CTD-ILD) is a rare but serious condition with limited clinical data; this study aimed to evaluate its clinical features, treat...

The introduction of immune checkpoint inhibitors (ICIs) has reshaped the therapeutic landscape of advanced non-small cell lung cancer. However, immune-related adverse events (irAEs), including rare cases of life-threaten...

IntroductionSystemic juvenile idiopathic arthritis-associated lung disease (sJIA-LD) is a rare, potentially fatal complication of sJIA, often accompanied by pulmonary hypertension (PHTN) and macrophage activation syndrom...

Cancer-associated fibroblasts (CAFs) are important stromal cells in the tumor microenvironment of lung adenocarcinoma (LUAD). This review discusses the different cellular sources of CAFs and the main signaling pathways i...

BackgroundMast cells are abundant throughout the lung, positioned near the airway epithelium, vasculature, and interstitium where they function as frontline sentinels to inhaled environmental and chemical stimuli. Throug...

IntroductionProgressive lung disease remains the leading cause of morbidity and mortality in patients with STAT3 hyper-IgE syndrome (HIES), despite optimal supportive care. Forced expiratory volume in 1 second (FEV1) is ...

BackgroundGranulomatous-lymphocytic interstitial lung disease (GLILD) is a noninfectious interstitial lung disorder characterized by granulomatous inflammation and lymphoid proliferation. It is most frequently identified...

ABSTRACT Background The COVID‐19 pandemic has caused massive devastation worldwide, and its effects still persist. Managing the early stages was difficult, but scientists worked tirelessly to control it. The emergence ...

BackgroundN-acetylcysteine (NAC) is a key precursor of glutathione (GSH), the lung’s principal antioxidant. First developed as a mucolytic, NAC is now recognized for broader antioxidant, anti-inflammatory, immunomodula...

BackgroundX-linked hyper-IgM syndrome (XHIM) due to CD40L deficiency typically presents in early childhood with recurrent sinopulmonary or opportunistic infections, and its initial manifestations can be misleading. We re...

Primary immune regulatory disorder (PIRD) is a subset of inborn errors of immunity (IEIs) caused by disruption of genes involved in regulating the immune response. PIRDs are predominantly characterized by dysregulated im...

Abstract Background Bacterial diseases include any illness caused by bacteria. Bacteria are tiny microorganisms that can only be seen with a microscope. Other types of microorganisms include viruses, fungi, and some para...

Abstract In this study, we described the morphological features and unusual presentations of hydatidosis, fasciolosis, and eosinophilic myositis caused by Sarcocystis species diagnosed at the slaughterhouse lines. Twenty...

Abstract Background Bronchoalveolar lavage (BAL) fluid cytology and culture are used to characterize respiratory diseases in dogs. Little is known about disorders associated with increased numbers of lymphocytes in BAL f...

A review of the literature revealed secondary amyloidosis (AA) associated with lung cancer in only 14 cases. With respect to the histological subtype, 8 of the cases were squamous cell carcinoma (SCC).Herein, we describe...

BackgroundItchy E3 ubiquitin ligase deficiency (ITCH deficiency) is a rare monogenic immune dysregulation syndrome characterized by early-onset multisystem autoimmunity and significant morbidity and mortality. Only one p...

Background: Ankylosing spondylitis (AS) frequently produces thoracic-cage deformities-kyphosis and rib fusion-that restrict chest expansion and impair ventilation, occasionally progressing to atelectasis or pulmonary fib...