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31 resultados encontrados.

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Ethnic-specific ZJU index thresholds for hepatic steatosis and fibrosis in Chinese MASLD
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Ethnic-specific ZJU index thresholds for hepatic steatosis and fibrosis in Chinese MASLD
Yu Qiu et al · Frontiers Media S.A · 2026 · ISSN 2296-858X
BackgroundThe Zhejiang University (ZJU) index correlates with metabolic dysfunction-associated steatotic liver disease (MASLD) in Chinese cohorts, but its ethnic-specific thresholds for hepatic steatosis and fibrosis rem...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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Lactic acid bacteria and endogenous ethanol mediate proton pump inhibitor-associated MASLD: a multicohort cross-sectional mediation analysis
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Lactic acid bacteria and endogenous ethanol mediate proton pump inhibitor-associated MASLD: a multicohort cross-sectional mediation analysis
Mark Davids et al · Taylor & Francis Group · 2026 · ISSN 1949-0976
Background & aims Proton pump inhibitor (PPI) use has been associated with metabolic dysfunction associated with steatotic liver disease (MASLD) in multiple studies. While the association is confounded by various risk fa...
LCC LCC:Diseases of the digestive system. GastroenterologyIdioma eng
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Mucin alleviates HFD-induced obesity and MASLD via an Akkermansia muciniphila-associated mucin-Neu5Ac-PPARα signaling axis
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Mucin alleviates HFD-induced obesity and MASLD via an Akkermansia muciniphila-associated mucin-Neu5Ac-PPARα signaling axis
Shaohui You et al · Elsevier · 2026 · ISSN 1096-1186
Mucin is known to modulate the gut environment; however, its specific mechanisms and downstream metabolites in alleviating obesity and hepatic steatosis remain unclear. In this study, we investigated the beneficial effec...
LCC LCC:Therapeutics. PharmacologyIdioma eng
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Preliminary insights into gut microbiome shifts as screening proxy for MASLD disease progression
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Preliminary insights into gut microbiome shifts as screening proxy for MASLD disease progression
M. Llirós Dupré et al · Nature Portfolio · 2026 · ISSN 2045-2322
Abstract Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD), a metabolic syndrome with chronic excessive non-alcohol related triglyceride accumulation in liver cells, is characterised by a gradient of hepat...
LCC LCC:Medicine; TENDOlNjaWVuY2U~Idioma eng
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β-Hydroxybutyrate upregulates hepatic histone β-hydroxybutyrylation modification, promotes the expression of PPARα, and alleviates the hepatic steatosis in MASLD
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β-Hydroxybutyrate upregulates hepatic histone β-hydroxybutyrylation modification, promotes the expression of PPARα, and alleviates the hepatic steatosis in MASLD
Dongze Li et al · BMC · 2026 · ISSN 1868-7083
Abstract Background Metabolic dysfunction-associated steatotic liver disease (MASLD) stands as the most widespread chronic liver disorder globally. Histone β-hydroxybutyrylation (Kbhb)—a novel post-translational modif...
LCC LCC:Medicine; LCC:GeneticsIdioma eng
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Global and regional prevalence, burden, and risk factors for MASLD in children and adolescents aged 5 to 24 years: a systematic review, meta-analysis, and modeling study
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Global and regional prevalence, burden, and risk factors for MASLD in children and adolescents aged 5 to 24 years: a systematic review, meta-analysis, and modeling study
Yunfei Liu et al · BMC · 2026 · ISSN 1741-7015
Abstract Background Obesity is associated with metabolic dysfunction-associated steatotic liver disease (MASLD). Despite the rising prevalence of obesity among children and adolescents, no studies have examined risk fact...
LCC LCC:MedicineIdioma eng
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Hepatocyte SLCO4C1 is a cAMP uptake transporter for inhibiting lipogenesis and a therapeutic target for MASLD
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Hepatocyte SLCO4C1 is a cAMP uptake transporter for inhibiting lipogenesis and a therapeutic target for MASLD
Xiaojia Huang et al · Nature Portfolio · 2026 · ISSN 2041-1723
Abstract Metabolic dysfunction-associated steatotic liver disease (MASLD), the most prevalent cause of chronic liver disease worldwide, currently lacks precision medicine treatments. SLCO4C1 acts as a transporter for end...
LCC TENDOlNjaWVuY2U~Idioma eng
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Research Progress on Nanoformulations Based on Active Components from Traditional Chinese Medicine for MASLD
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Research Progress on Nanoformulations Based on Active Components from Traditional Chinese Medicine for MASLD
Gou ZX et al · Dove Medical Press · 2026 · ISSN 1178-2013
Zi-Xiu Gou, Ning-Wei Li, Jun-Yi Yao, Yun-Liang Wang Department of Gastroenterology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, People’s Republic of ChinaCorrespondence: Yun-Liang Wang, Departme...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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Sex-specific dynamics of MASLD reveal early hepatic and extrahepatic metabolic deterioration in females despite long-term protection
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Sex-specific dynamics of MASLD reveal early hepatic and extrahepatic metabolic deterioration in females despite long-term protection
Maria Repollés-de-Dalmau et al · BMC · 2026 · ISSN 2042-6410
Abstract Background Metabolic dysfunction-associated steatotic liver disease (MASLD) is a chronic condition characterized by hepatic fat accumulation and systemic metabolic dysfunction. MASLD exhibits clear sex differenc...
LCC LCC:Medicine; TENDOlBoeXNpb2xvZ3k~Idioma eng
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Comment on: Metabolic comorbidities and post-transplant outcomes in Metabolic dysfunction-Associated Steatotic Liver Disease (MASLD): a cohort study from a Brazilian tertiary center
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Comment on: Metabolic comorbidities and post-transplant outcomes in Metabolic dysfunction-Associated Steatotic Liver Disease (MASLD): a cohort study from a Brazilian tertiary center
Zainab Mumtaz et al · Sociedade Brasileira de Endocrinologia e Metabologia · 2026 · ISSN 2359-4292
LCC LCC:Medicine; LCC:Diseases of the endocrine glands. Clinical endocrinologyIdioma eng
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Response to the letter to the editor: Metabolic comorbidities and post-transplant outcomes in Metabolic dysfunction-Associated Steatotic Liver Disease (MASLD): a cohort study from a Brazilian tertiary center
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Response to the letter to the editor: Metabolic comorbidities and post-transplant outcomes in Metabolic dysfunction-Associated Steatotic Liver Disease (MASLD): a cohort study from a Brazilian tertiary center
Felipe Ramos Caprini et al · Sociedade Brasileira de Endocrinologia e Metabologia · 2026 · ISSN 2359-4292
LCC LCC:Medicine; LCC:Diseases of the endocrine glands. Clinical endocrinologyIdioma eng
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Epigenetic signatures and cellular stress response pathways in metabolic dysfunction-associated steatotic liver disease: a personalized medicine perspective
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Epigenetic signatures and cellular stress response pathways in metabolic dysfunction-associated steatotic liver disease: a personalized medicine perspective
Fabian M. Cortés-Mancera et al · Frontiers Media S.A · 2026 · ISSN 1664-042X
Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common chronic liver disease around the world, with at least 40% global prevalence. Although genetic susceptibility contributes to disease risk...
LCC TENDOlBoeXNpb2xvZ3k~Idioma eng
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Liver Stiffness Directs Intrahepatic Cholesterol Accumulation Through YAP/TAZ in Metabolic Dysfunction‐Associated Steatotic Liver Disease
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Liver Stiffness Directs Intrahepatic Cholesterol Accumulation Through YAP/TAZ in Metabolic Dysfunction‐Associated Steatotic Liver Disease
Na Young Lee et al · Wiley · 2026 · ISSN 2198-3844
ABSTRACT Elevated liver stiffness is closely associated with morbidity and mortality in metabolic dysfunction‐associated steatotic liver disease (MASLD). However, the contribution of increased stiffness to impaired liv...
LCC TENDOlNjaWVuY2U~Idioma eng
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Markers of Hepatic Insulin Clearance and Their Association With Steatosis in Hyperinsulinaemic Horses
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Markers of Hepatic Insulin Clearance and Their Association With Steatosis in Hyperinsulinaemic Horses
Miranda Dosi et al · Oxford University Press · 2025 · ISSN 0891-6640
ABSTRACT Background Hyperinsulinaemia (HI) is an important feature of Equine Metabolic Syndrome (EMS). It has been suggested that reduced hepatic clearance of insulin contributes to HI, particularly in humans affected by...
LCC TENDOlZldGVyaW5hcnkgbWVkaWNpbmU~Idioma eng
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OneSTOP (One-Stop Telehealth Obesity Program): study protocol for an open-label randomized controlled trial on the use of telecare and digital platforms for multidisciplinary management of weight management and related comorbidities
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OneSTOP (One-Stop Telehealth Obesity Program): study protocol for an open-label randomized controlled trial on the use of telecare and digital platforms for multidisciplinary management of weight management and related comorbidities
Joan Khoo et al · BMC · 2026 · ISSN 1745-6215
Abstract Background Obesity is prevalent in Singapore and is a driver of multiple co-morbidities including type 2 diabetes, metabolic dysfunction associated steatotic liver disease (MASLD), and cardiovascular disease. Tr...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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Postoperative complication risk following carpometacarpal arthroplasty in patients with non-alcoholic fatty liver disease versus non-alcoholic cirrhosis: A matched cohort study
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Postoperative complication risk following carpometacarpal arthroplasty in patients with non-alcoholic fatty liver disease versus non-alcoholic cirrhosis: A matched cohort study
Catherine Hand et al · Elsevier · 2026 · ISSN 2773-157X
Introduction: As the prevalence of metabolic dysfunction–associated steatotic liver disease (MASLD), formerly NAFLD, continues to rise, increasing numbers of patients with hepatic dysfunction are undergoing elective or...
LCC TENDOk9ydGhvcGVkaWMgc3VyZ2VyeQ~~Idioma eng
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Semaglutide 2.4 mg for Obese Patients with MASH: A Cost-Effectiveness Analysis from the Italian NHS Perspective
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Semaglutide 2.4 mg for Obese Patients with MASH: A Cost-Effectiveness Analysis from the Italian NHS Perspective
Torre E et al · Dove Medical Press · 2026 · ISSN 1178-6981
Enrico Torre,1 Sergio Di Matteo,2 Chiara Martinotti,2 Giacomo Matteo Bruno,3 Alessandro Cabrino,2 Emma Lucia Fogliati,2 Andrea Giusti,4 Marco Barbieri,5 Luigi Carlo Bottaro,6 Giorgio Lorenzo Colombo3 1Diabetology and Met...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~; LCC:Therapeutics. PharmacologyIdioma eng
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Editorial: Research in obesity, type 2 diabetes, and metabolic syndrome: cellular pathways and therapeutic innovations
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Editorial: Research in obesity, type 2 diabetes, and metabolic syndrome: cellular pathways and therapeutic innovations
Mayank Choubey et al · Frontiers Media S.A · 2026 · ISSN 2296-634X
Materias / palabras clave: adiposity; chronic diseases; MASH; MASLD; metabolic syndrome; obesity
LCC LCC:Biology (General)Idioma eng
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Therapeutic role of JAK inhibitors in hepatogastrointestinal diseases
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Therapeutic role of JAK inhibitors in hepatogastrointestinal diseases
Maged Tharwat Elghannam et al · Open Exploration Publishing Inc · 2026 · ISSN 2833-6321
Janus kinase (JAK) inhibitors represent a major advancement in the management of immune-mediated inflammatory diseases. A balanced approach that carefully weighs therapeutic benefits against potential risks is essential....
LCC LCC:Diseases of the digestive system. GastroenterologyIdioma eng
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AI-powered ultrasound radiofrequency analysis for non-invasive pediatric liver fat quantification
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AI-powered ultrasound radiofrequency analysis for non-invasive pediatric liver fat quantification
Gayoung Choi et al · Nature Portfolio · 2026 · ISSN 2045-2322
Abstract Metabolic dysfunction-Associated Steatotic Liver Disease (MASLD) affects 30–50% of obese children, yet accurate non-invasive quantification remains challenging. While magnetic resonance imaging-proton density ...
LCC LCC:Medicine; TENDOlNjaWVuY2U~Idioma eng
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Alcohol intake and markers of liver health in patients with type 2 diabetes and metabolic dysfunction–associated steatotic liver disease
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Alcohol intake and markers of liver health in patients with type 2 diabetes and metabolic dysfunction–associated steatotic liver disease
Cernea Simona et al · Sciendo · 2026 · ISSN 2668-7763
Objective: The study evaluated the impact of low-level alcohol intake on liver health in patients with type 2 diabetes (T2DM) and metabolic dysfunction–associated steatotic liver disease (MASLD).
LCC LCC:MedicineIdioma eng
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Association of serum uric acid and serum uric acid/creatinine ratio with metabolic dysfunction-associated fatty liver disease in young adults: a retrospective study
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Association of serum uric acid and serum uric acid/creatinine ratio with metabolic dysfunction-associated fatty liver disease in young adults: a retrospective study
Yue Li et al · BMC · 2026 · ISSN 1472-6823
Abstract Background Metabolic dysfunction-associatedsteatotic liver disease (MASLD) has become the most prevalent chronic liver disease worldwide. Its incidence continues to rise with a marked trend toward younger age gr...
LCC LCC:Diseases of the endocrine glands. Clinical endocrinologyIdioma eng
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Associations of systemic inflammation response index and systemic immune-inflammation index with proxy-assessed sarcopenia in community-dwelling older adults
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Associations of systemic inflammation response index and systemic immune-inflammation index with proxy-assessed sarcopenia in community-dwelling older adults
Min Tang et al · Frontiers Media S.A · 2026 · ISSN 2296-858X
ObjectiveSarcopenia is a progressive and complex disorder associated with higher morbidity and mortality, which significantly increases the financial burden and medical costs. This study aims to investigate the relations...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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Bidirectional association between non-steatotic chronic liver disease and heart disease: the potential link of insulin resistance
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Bidirectional association between non-steatotic chronic liver disease and heart disease: the potential link of insulin resistance
Yan Zhang et al · BMC · 2026 · ISSN 1475-2840
Abstract Background Chronic liver disease (CLD) and heart disease (HD) are major contributors to global morbidity and mortality. Although increasing evidence supports close interactions between the liver and heart, popul...
LCC TENDOkRpc2Vhc2VzIG9mIHRoZSBjaXJjdWxhdG9yeSAoQ2FyZGlvdmFzY3VsYXIpIHN5c3RlbQ~~Idioma eng
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