Buscar recursos académicos

Background: Outer membrane vesicles (OMVs) from Gram-negative bacteria are spherical lipid bilayer nanostructures with diameters of 20 to 250 nm. Porphyromonas gingivalis (P. gingivalis), a keystone periodontal pathogen,...

ABSTRACT Background and Aims Prelabor rupture of membranes is a significant obstetric complication with serious maternal and neonatal consequences. Hypertensive disorders of pregnancy are among the leading contributors t...

Water build-up has continued to be one of the leading causes of performance variability and loss of durability in proton exchange membrane fuel cells (PEMFCs), especially at the high current density and transient operati...

ABSTRACT Proton exchange membrane water electrolysis (PEMWE) is a compelling route for sustainable green hydrogen production. Yet Ir‐based oxygen evolution reaction (OER) catalysts suffer from a persistent trade‐off ...

Developing cost-effective and highly durable electrocatalysts to overcome the sluggish kinetics of the oxygen reduction reaction (ORR) is critical for the promotion of proton exchange membrane fuel cells (PEMFCs). In thi...

Recently, some evaluations of the workers' and students' abilities brought back to consider the negative (or reverse) Flynn effect. The reverse Flynn effect is an empirically confirmed decrease in the Intelligence Quotie...

ABSTRACT Background and Aims Extracorporeal life support (ECLS) is a critical intervention in the management of severe cardiac and respiratory failure. Among the commonly used cannulation techniques, percutaneous cannula...

Li Tao,1,2,* Meiling Tai,3,* Zhuang Zhou,3 Zhenwen Chen,1 Rongjinlei Zhang,1 Yuanlong Ge,1 Zhenyu Ju1 1Key Laboratory of Regenerative Medicine of Ministry of Education, Institute of Aging and Regenerative...

Abstract The rapid adoption of AI is transforming industrial wastewater treatment by enabling real-time monitoring, predictive control, and operational optimization. Publications on the subject accelerated sharply betwee...

Abstract Background This systematic review and meta-analysis evaluates the safety and efficacy of emerging prostate-specific membrane antigen (PSMA) radioligand therapy (RLT) agents used beyond [¹⁷⁷Lu]Lu-PSMA in met...

ABSTRACT Background Lead is a nonessential, toxic heavy metal that causes widespread environmental contamination, affecting humans, animals, plants, and ecosystems. Globally, an estimated 800 million children have blood ...

ABSTRACT Background Mpox is a zoonotic viral disease caused by the monkeypox virus, with potential for significant morbidity across all population groups, including pregnant individuals and neonates. Pregnancy represents...

Herbal medicines have been extensively used for centuries owing to their therapeutic benefits and comparatively low incidence of adverse effects. Despite their clinical potential, the effectiveness of many herbal formula...

IntroductionPancreatic ductal adenocarcinoma (PDAC) remains one of the most aggressive and invasive malignancies, with limited response to the currently available systemic therapy options. Having a 5-year survival of 12%...

Brucellosis, a zoonotic disease, triggers severe inflammation and reproductive complications in both humans and animals. The standard treatment protocol relies on prolonged antibiotic courses, often combining streptomyci...

ABSTRACT Platelets are crucial to the development of thrombosis and coagulation abnormalities in sepsis, but the mechanisms by which they contribute to these pathological processes are not fully understood. Here, we iden...

mRNA vaccines emerged as a leading vaccine technology during the COVID-19 pandemic. However, their sustained protective efficacies were limited by relatively short-lived antibody responses and the emergence of SARS-CoV-2...

Mitochondria orchestrate energy conversion and cell fate, yet label-free approaches that report both functional and physical states at the single-organelle level are nonexistent. Here, we combine atomic force microscopy ...

ABSTRACT Selective recognition of cancer‐associated proteins (CAPs) by antibodies, followed by their delivery into the intracellular organelle, the lysosome, results in targeted degradation of CAPs and suppresses the g...

Surface adhesion is critical to the survival of pathogenic bacteria both in natural niches and during infections, often via forming matrix-embedded communities called biofilms. Vibrio cholerae, the causal agent of pandem...

We reveal a coordinating role for Cx32-mediated cell–cell communication in maintaining mitotic-quiescence and limiting migration-associated TGFβ signalling, extracellular matrix remodelling and mesenchymal-like change...

The inadequate corrosion resistance and conductivity of metal bipolar plates are major obstacles to the commercialization of proton exchange membrane water electrolysis (PEMWE). In this work, Nb/NbN/Mo-containing NbN mul...

IntroductionPennycress (Thlaspi arvense L.) is an emerging intermediate oilseed crop grown in the offseason between primary summer crops to produce three cash crops in two years. Previous efforts to improve seed oil qual...

Sequestosome 1/p62 (hereafter referred to as p62) is a multifunctional protein that orchestrates various cellular stress response pathways including autophagy, proteasome-mediated degradation, antioxidant defense, nutrie...