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In our study, we designed forty-one caffeine analogs with the aim of improving the modulation of acetylcholinesterase (AchE, PDBid: 4EY7) and activating the neuronal nicotinic acetylcholine receptor (α7-nAchR, PDBid: 7E...

Los pequeños bagres del género Microglanis, con 29 especies válidas, habitan desde Guyana hasta la baja cuenca del Plata. La única especie presente en aguas argentinas antes de las descripciones de M. carlae y M. nig...

Computer-aided drug discovery and design involve the use of information technologies to identify and develop, on a rational ground, chemical compounds that align a set of desired physicochemical and biological properties...

"The stabilization of pores can be studied by different approaches such as simulations in silico or experimental procedures in vivo or in vitro. The energy to open a pore in a lipid membrane can be delivered by different...