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ObjectiveTo develop a rapid method for the screening and identification of foodborne （C. perfringens） isolates using multiple nucleic acid detection system combined with matrix assisted laser desorpt ionionization ti...

Abstract Background Staphylococcus aureus skin infections represent a persistent clinical challenge owing to their high pathogenicity, multidrug resistance, and biofilm-associated recurrence, which collectively impair an...

Abstract The global emergence and spread of infectious diseases highlights the importance of having an easily accessible, decentralized testing modality that is adept at quickly identifying the nucleic acids present in a...

Abstract Old World orthohantaviruses, including Hantaan virus (HTNV), cause hemorrhagic fever with renal syndrome (HFRS) in Eurasia. Available inactivated vaccines often induce low neutralizing antibodies and short-term ...

ObjectiveTo address the false-negative risk associated with trace contamination of severe acute respiratory syndrome coronavirus 2 （SARS-CoV-2） on cold-chain food and packaging material surfaces， this study aimed t...

Abstract The objective of this study was to characterize the meat quality traits that affect the texture and savory taste of Ufipa indigenous chickens by comparing the proximate composition, physical characteristics, col...

Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease of unknown etiology. Several signaling pathways associated with oxidative stress, such as Nrf2, NOX and NF-κB, have been implicated in the pathogenesis ...

Phosphorus (P) is an essential mineral nutrient for plants, playing central roles in development, growth, and environmental responses. In the soil, P is available in the form of inorganic phosphate (Pi), which, once inco...

Abstract Periodontitis is the most prevalent chronic inflammatory condition affecting oral health and is associated with long treatment duration. It is triggered by microbial plaque, which leads to localized and diffuse ...

Abstract Background Infection by coronaviruses cause gastrointestinal disease in many species. Little is known about its prevalence and importance in goats. Objective Identify the etiology, demographics, and clinical fea...

Abstract Introduction In December 2022, the zero - COVID strategy was amended, eliminating mandatory testing and isolation. The purpose of this study was to explore the effectiveness of targeted prevention measures in a ...

Abstract Infectious disease diagnostics has been transformed by metagenomic next‐generation sequencing (mNGS), an unbiased approach that detects bacteria, viruses, fungi, and parasites in a single assay. By sequencing ...

Abstract Background Chronic endometritis (CE) has two principal subtypes—non-specific chronic endometritis (NSCE) and endometrial tuberculosis (ETB). Both can adversely affect embryo implantation. Although ETB is gener...

Background: WHO International Standards (IS) are provided for the calibration and validation of diagnostic and screening assays, e.g. for hepatitis B virus (HBV). HBV forms numerous subgenotypes and the current IS for HB...

PurposePreimplantation genetic testing for aneuploidy (PGT-A) is essential for selecting embryos free from chromosomal abnormalities before transfer. However, challenges such as detection failures, mosaicism, and the lim...

IntroductionNeutrophils, the most abundant leukocyte population, play a central role in host defense against group B Streptococcus (GBS), an encapsulated bacterium that frequently causes severe infections in humans, incl...

Orf virus causes infections in sheep and goats with lesions especially around muzzle and mouth. The disease is widespread, and most sheep-rearing countries are not free of infection. Disease is caused by ORF virus (ORFV)...

Introduction: Cancer patients often come across infections, which disturb their treatment regimen and raise the chances for serious complications. Aim of Study: To study the microbiological profile of infections and ant...

Interferonopathies are rare autoinflammatory disorders driven by a constitutive upregulation of the type I interferon (IFN-I) pathway, leading to chronic activation of this cytokine. Despite advances, direct IFN-I measur...

Abstract Background Non‐suppurative encephalitides in a variety of species, including humans and dogs, have been linked to infection by astroviruses and bornaviruses. Hypothesis/Objectives To determine whether or not r...

BackgroundCoxiella burnetii is the causative agent of Q fever, a zoonotic infection that poses serious threats to both animal and human health, particularly in the Global South. It infects livestock such as cattle, sheep...

The rising concern of antimicrobial resistance, coupled with the continually challenging management of complicated diseases such as cancer, has provided momentum toward precision molecular medicine. This review provides ...

Abstract Phase separation (PS) of biomolecular condensates is often assumed to be driven by interactions involving nucleic acids and intrinsically disordered regions (IDRs) of proteins. PGL-3 is a component of P granules...

Free radicals are molecules which contain one or more unpaired electrons. These molecules are highly reactive and tend to initiate chain reactions with other molecules also called oxidants or reactive oxygen particles (R...