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16 resultados encontrados.

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Tetrahedral framework nucleic acid delivery of emodin enables precision antibacterial and anti-inflammatory therapy for drug-resistant Staphylococcus aureus
Artículo
Material complementario disponible Artículo DOAJ
Peitong Jiang et al · BMC · 2026 · ISSN 1477-3155
Abstract Background Staphylococcus aureus skin infections represent a persistent clinical challenge owing to their high pathogenicity, multidrug resistance, and biofilm-associated recurrence, which collectively impair an...
LCC TENDOkJpb3RlY2hub2xvZ3k~; TENDOk1lZGljYWwgdGVjaG5vbG9neQ~~Idioma eng
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Trends of nucleic acid – based point-of-care diagnostics for infectious diseases
Artículo
Material complementario disponible Artículo DOAJ
Hossam Hatem et al · BMC · 2026 · ISSN 1754-1611
Abstract The global emergence and spread of infectious diseases highlights the importance of having an easily accessible, decentralized testing modality that is adept at quickly identifying the nucleic acids present in a...
LCC LCC:Biology (General)Idioma eng
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A matter of quantity: The effect of chloroplast stromal phosphate levels on photosynthetic efficiency
Artículo
Acceso abierto Artículo CONICET Digital
Calzadilla, Pablo Ignacio · American Society of Plant Biologist · 2024 · ISSN 0032-0889
Phosphorus (P) is an essential mineral nutrient for plants, playing central roles in development, growth, and environmental responses. In the soil, P is available in the form of inorganic phosphate (Pi), which, once inco...
Idioma eng
Acceso abiertoRuta libre sin proxy. Acceso recomendado cuando no hay suscripción activa.
Open Access
DNA framework-based nanomedicine platform: a triple-function strategy for treating periodontitis via antibacterial, anti-inflammatory, and osteogenesis-promoting activities
Artículo
Acceso abierto Artículo DOAJ
Geru Zhang et al · Nature Publishing Group · 2026 · ISSN 2049-3169
Abstract Periodontitis is the most prevalent chronic inflammatory condition affecting oral health and is associated with long treatment duration. It is triggered by microbial plaque, which leads to localized and diffuse ...
LCC TENDOkRlbnRpc3RyeQ~~Idioma eng
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Open Access
Diarrhea outbreak associated with coronavirus infection in adult dairy goats
Artículo
Material complementario disponible Artículo DOAJ
Fauna Leah Smith et al · Oxford University Press · 2022 · ISSN 0891-6640
Abstract Background Infection by coronaviruses cause gastrointestinal disease in many species. Little is known about its prevalence and importance in goats. Objective Identify the etiology, demographics, and clinical fea...
LCC TENDOlZldGVyaW5hcnkgbWVkaWNpbmU~Idioma eng
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Emerging role of metagenomic next‐generation sequencing in infectious disease diagnostics: Clinical integration and future directions
Artículo
Acceso abierto Artículo DOAJ
Tingting Fang et al · Wiley · 2026 · ISSN 2770-100X
Abstract Infectious disease diagnostics has been transformed by metagenomic next‐generation sequencing (mNGS), an unbiased approach that detects bacteria, viruses, fungi, and parasites in a single assay. By sequencing ...
LCC TENDOk1pY3JvYmlvbG9neQ~~Idioma eng
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Human neutrophils recognize group B streptococci via formylated peptide receptors and toll-like receptor 8
Artículo
Acceso abierto Artículo DOAJ
Luigi Fiore et al · Frontiers Media S.A · 2026 · ISSN 1664-3224
IntroductionNeutrophils, the most abundant leukocyte population, play a central role in host defense against group B Streptococcus (GBS), an encapsulated bacterium that frequently causes severe infections in humans, incl...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Open Access
Investigation of astrovirus and bornavirus in the cerebrospinal fluid of dogs clinically diagnosed with meningoencephalitis of unknown etiology
Artículo
Material complementario disponible Artículo DOAJ
Audrey Collinet et al · Oxford University Press · 2020 · ISSN 0891-6640
Abstract Background Non‐suppurative encephalitides in a variety of species, including humans and dogs, have been linked to infection by astroviruses and bornaviruses. Hypothesis/Objectives To determine whether or not r...
LCC TENDOlZldGVyaW5hcnkgbWVkaWNpbmU~Idioma eng
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Molecular characterization of Coxiella burnetii in livestock species in Isiolo County, Kenya and the associated risks factors for seropositivity
Artículo
Acceso abierto Artículo DOAJ
Enock Kiprono et al · Frontiers Media S.A · 2026 · ISSN 2297-1769
BackgroundCoxiella burnetii is the causative agent of Q fever, a zoonotic infection that poses serious threats to both animal and human health, particularly in the Global South. It infects livestock such as cattle, sheep...
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Open Access
Phage enabled precision drug delivery: dual function platforms for therapeutics and genetic cargo transport
Artículo
Acceso abierto Artículo DOAJ
Md. Sharifull Islam et al · Frontiers Media S.A · 2026 · ISSN 1664-302X
The rising concern of antimicrobial resistance, coupled with the continually challenging management of complicated diseases such as cancer, has provided momentum toward precision molecular medicine. This review provides ...
LCC TENDOk1pY3JvYmlvbG9neQ~~Idioma eng
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Phase separation of PGL-3 driven by structured domains that oligomerize and interact with RGG motifs
Artículo
Acceso abierto Artículo DOAJ
Rimpei Kuroiwa et al · Springer Nature · 2026 · ISSN 1469-3178
Abstract Phase separation (PS) of biomolecular condensates is often assumed to be driven by interactions involving nucleic acids and intrinsically disordered regions (IDRs) of proteins. PGL-3 is a component of P granules...
LCC LCC:Biology (General)Idioma eng
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Open Access
REACTIVE OXYGEN PARTICLES AND ANTIOXIDANT DEFENCE
Artículo
Acceso abierto Artículo DOAJ
Caner ÇAVDAR et al · Turkish Society of Nephrology · 2019 · ISSN 2667-4440
Free radicals are molecules which contain one or more unpaired electrons. These molecules are highly reactive and tend to initiate chain reactions with other molecules also called oxidants or reactive oxygen particles (R...
LCC LCC:Internal medicine; TENDOlBlZGlhdHJpY3M~Idioma eng
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Recent advances in optical label-free characterization of extracellular vesicles
Artículo
Acceso abierto Artículo DOAJ
Imanbekova Meruyert et al · Wiley · 2022 · ISSN 2192-8606
Extracellular vesicles (EVs) are complex biological nanoparticles endogenously secreted by all eukaryotic cells. EVs carry a specific molecular cargo of proteins, lipids, and nucleic acids derived from cells of origin an...
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Research progress on the interaction mechanisms and functions between exosomes and the cytoskeleton
Artículo
Acceso abierto Artículo DOAJ
Shili Yang et al · Frontiers Media S.A · 2026 · ISSN 2296-634X
Exosomes, as key mediators of intercellular communication, play a central regulatory role in cellular physiological and pathological processes through their dynamic interaction with the cytoskeleton. The cytoskeleton is ...
LCC LCC:Biology (General)Idioma eng
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Sensibilidade da PCR na amplificação do DNA bovino em diluição seriada e mistura de amostra macho e fêmea
Artículo
Acceso abierto Artículo DOAJ
A.S. Cruz et al · Universidade Federal de Minas Gerais, Escola de Veterinária · 2011 · ISSN 1678-4162
A mixture of bovine DNA from a male and a female Jersey (Bos taurus taurus) bred in different proportions was used to determine the sensitivity of PCR to amplify and discriminate the bovine DNA samples. Samples were obta...
LCC LCC:Animal cultureIdioma eng
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Transposable elements as a possible missing link between genetic predisposition and environmental triggers of autoimmune disorders: insights from type 1 diabetes, systemic lupus erythematosus and rheumatoid arthritis
Artículo
Material complementario disponible Artículo DOAJ
Karolina Mužina et al · Frontiers Media S.A · 2026 · ISSN 1664-3224
Transposable elements (TEs) make up almost half of the human genome and are among its most densely methylated regions. Their epigenetic silencing is crucial for genomic stability and immune homeostasis, and accumulating ...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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