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Background and Aim: Brucellosis is a chronic infectious disease of cattle that may influence not only animal health but also the nutritional and sanitary quality of meat. While veterinary–sanitary implications of infec...

Recently, agricultural productivity and food security have been seriously threatened by climate changes, which has increased poverty globally. So, it is necessary to address these changes and minimize their detrimental i...

BackgroundImmune checkpoint inhibitors (ICIs) have transformed treatment of locally advanced gastric cancer (LAGC), yet response heterogeneity and immune-related adverse events (irAEs) remain major challenges. Systemic i...

Abstract Background and aim Severe pneumonia is associated with high mortality rates. Nutritional and inflammatory status significantly impacts outcomes. While albumin-based indices have been demonstrated to predict outc...

Soybeans hold a deep cultural significance with its origin in Asia. All of the current modern cultivars belong to the same Glycine max (L.) Merrill, which can be distinguished primarily by their seed coat pigmentation. T...

The increasing lack and limitations of key cereals such as rice and wheat, aggravated by climate change, growing population, and declining agricultural sustainability, pose significant threats to global food and nutritio...

Neurodegenerative disorders represent a major and growing global health challenge, characterized by progressive neuronal loss, multifactorial pathophysiology, and limited disease-modifying pharmacological options. Increa...

Abstract Background Frailty is strongly associated with adverse outcomes including depression, cognitive decline, falls, and reduced quality of life. Frailty is an important indicator of older individuals’ health statu...

Abstract Purpose Eating disorders (EDs) among women of childbearing age (WCBA; defined by the World Health Organization as women aged 15–49 years) have emerged as a significant public health concern on a global scale. ...

Abstract Background Discordance between small dense low-density lipoprotein cholesterol (sdLDL-C) and low-density lipoprotein cholesterol (LDL-C) levels is common. Whether this easily calculated parameter, derived from r...

Abstract Background Epidemiological data consistently associate low vitamin D status with elevated cardiovascular risk, yet causal mechanisms remain contested. Methods This review synthesized evidence through a protocol-...

Abstract Objective Tuberculosis (TB) remains a global health threat with an incompletely understood pathogenesis. The RNA epigenetic modification N6-methyladenosine (m6A) is a key regulator of immune responses in various...

Enterotoxaemia remains one of the most severe and rapidly fatal diseases affecting goats, mainly caused by Clostridium perfringens types C and D. Despite widespread vaccination practices, the disease continues to produce...

Abstract Background In Hatay, Türkiye, which suffered extensive devastation from the earthquake of 2023, people were living in container cities during the recovery process. While the physical and psychological effects o...

Micronutrients serve as critical metabolic sensors and epigenetic regulators that orchestrate cytokine production through multiple overlapping signalling cascades, transcriptional networks, and cellular metabolic states....

Abstract Neuroimmunological diseases arise from a complex interplay of genetic susceptibility, environmental exposures, and immune-mediated mechanisms. In this context, modifiable lifestyle and environmental factors may ...

Abstract Background Proper eating/fasting cycle can regulate circadian rhythms, thereby influencing metabolic regulation, oxidative stress, and cognitive function. However, its association with overall health remains und...

Celiac disease (CD) and Hashimoto’s thyroiditis (HT) frequently coexist, suggesting that shared mechanisms of autoimmunity extend beyond the intestine. In CD, the pathogenic role of gluten is firmly established; in HT,...

ObjectiveExcessive secretion of inflammatory biomarkers exerts adverse effects on muscle strength and function, and is associated with the development and progression of sarcopenia and frailty. For the improvement of inf...

IntroductionThe aquaculture industry has been exploring new methods to enhance fish production, including using amino acids as supplements to boost growth and health. L-glutamate (Glu) is one of the most abundant amino a...

Pregnancy is accompanied by complex physiological adaptations that influence hepatic metabolism, bile transport, coagulation, and immune tolerance, which may precipitate the development of pregnancy-specific liver disord...

Abstract Background Obesity is a significant contributor to global morbidity and mortality, driven by rising consumption of unhealthy energy dense foods high in salt, sugar and fat (HFSS). Supermarkets, pivotal in food d...

Abstract Objective: To estimate the effect of integrating responsive care, early learning and development monitoring into a community-based package of activities on nutrition, sanitation and hygiene, on improvements in ...

The gut microbiota has co-evolved with its host and forms an essential component of the human body. It is acquired at birth and continues to develop alongside the host, preserving its diversity and stability throughout l...