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Management of type II tibial spine fractures in children and adolescents: a systematic review
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Management of type II tibial spine fractures in children and adolescents: a systematic review
Marco Sapienza et al · BMC · 2026 · ISSN 1749-799X
Abstract Background Tibial spine avulsion fractures (TSFs) are the pediatric equivalent of anterior cruciate ligament (ACL) injuries. The optimal management of type II fractures remains debated, and both conservative and...
LCC TENDOk9ydGhvcGVkaWMgc3VyZ2VyeQ~~; LCC:Diseases of the musculoskeletal systemIdioma eng
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Case Report: Treatment of refractory lung disease in systemic juvenile idiopathic arthritis with cyclophosphamide and rituximab combination therapy
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Case Report: Treatment of refractory lung disease in systemic juvenile idiopathic arthritis with cyclophosphamide and rituximab combination therapy
William J. Freeman et al · Frontiers Media S.A · 2026 · ISSN 1664-3224
IntroductionSystemic juvenile idiopathic arthritis-associated lung disease (sJIA-LD) is a rare, potentially fatal complication of sJIA, often accompanied by pulmonary hypertension (PHTN) and macrophage activation syndrom...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Development and internal validation of a machine learning-based model for predicting 2-year mortality in interstitial lung disease
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Development and internal validation of a machine learning-based model for predicting 2-year mortality in interstitial lung disease
Xingyu Jin et al · BMC · 2026 · ISSN 1465-993X
Abstract Background Interstitial lung disease (ILD) is characterized by marked heterogeneity and an overall poor prognosis, with many patients experiencing rapid progression and high short-term mortality. Accurate early ...
LCC TENDOkRpc2Vhc2VzIG9mIHRoZSByZXNwaXJhdG9yeSBzeXN0ZW0~Idioma eng
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Dyspnea, eosinopenia, consolidation, acidemia, atrial fibrillation and confusion, urea, respiratory rate, blood pressure, and age-65 as a prognostic indicator in patients with acute exacerbation of chronic obstructive pulmonary disease
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Dyspnea, eosinopenia, consolidation, acidemia, atrial fibrillation and confusion, urea, respiratory rate, blood pressure, and age-65 as a prognostic indicator in patients with acute exacerbation of chronic obstructive pulmonary disease
Radhakrishna RK et al · Manipal College of Medical Sciences, Pokhara · 2026 · ISSN 2467-9100
Background: Chronic obstructive pulmonary disease (COPD) is a prevalent chronic illness characterized by persistent airflow limitation. Episodes of acute worsening, known as acute exacerbations of COPD (AECOPD), represen...
LCC LCC:MedicineIdioma eng
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A review of the impact of isolated antiphospholipid antibody positivity on pregnancy outcomes and clinical management strategies
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A review of the impact of isolated antiphospholipid antibody positivity on pregnancy outcomes and clinical management strategies
Xiangrui Wang et al · Frontiers Media S.A · 2026 · ISSN 1664-3224
ObjectiveThis review summarizes the current evidence on the impact of isolated antiphospholipid antibody positivity (IAAP) on pregnancy outcomes. It analyzes risk differentials across antibody subtypes, synthesizes the u...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Advances in the Management of Hepatocellular Carcinoma: Evolving Systemic Therapy, Perioperative Strategies, and Care for Special Populations
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Advances in the Management of Hepatocellular Carcinoma: Evolving Systemic Therapy, Perioperative Strategies, and Care for Special Populations
Jing He et al · Gleam Publishing · 2026 · ISSN 2759-534X
Hepatocellular carcinoma (HCC) remains the dominant histologic subtype of primary liver cancer and a major cause of cancer mortality worldwide. Its epidemiology continues to evolve, with metabolic dysfunction-associated ...
LCC LCC:MedicineIdioma eng
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Barriers to hypertension management in a developing country: a qualitative study among patients with hypertension at the National Hospital of Sri Lanka
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Barriers to hypertension management in a developing country: a qualitative study among patients with hypertension at the National Hospital of Sri Lanka
Priyanga Ranasinghe et al · BMC · 2026 · ISSN 1471-2458
Abstract Background A rapidly rising prevalence of hypertension (HTN) is observed in low-and-middle-income countries but few studies explore factors such as attitudes and beliefs, experiences and social and cultural cond...
LCC LCC:Public aspects of medicineIdioma eng
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Clinical Relationship between Cholestatic Disease and Pituitary‐Dependent Hyperadrenocorticism in Dogs: A Retrospective Case Series
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Clinical Relationship between Cholestatic Disease and Pituitary‐Dependent Hyperadrenocorticism in Dogs: A Retrospective Case Series
K.‐h. Kim et al · Oxford University Press · 2017 · ISSN 0891-6640
Background A high prevalence of cholestatic disease, including gallbladder mucocele (GBM), has been reported in dogs with naturally occurring pituitary‐dependent hyperadrenocorticism (PDH). Hypothesis/Objectives Differ...
LCC TENDOlZldGVyaW5hcnkgbWVkaWNpbmU~Idioma eng
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Clinicopathological landscape and management trends of thyroid carcinoma over two decades: a single-institution study and risk stratification of central lymph node metastasis in T1 papillary thyroid carcinoma
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Clinicopathological landscape and management trends of thyroid carcinoma over two decades: a single-institution study and risk stratification of central lymph node metastasis in T1 papillary thyroid carcinoma
Li’nan Qin et al · Frontiers Media S.A · 2026 · ISSN 1664-2392
PurposeThis study aimed to describe the clinicopathological landscape of thyroid disease, summarize long-term management trends of thyroid carcinoma (TC) and lymph node metastasis (LNM) from 1999 to 2018, and develop a n...
LCC LCC:Diseases of the endocrine glands. Clinical endocrinologyIdioma eng
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The effect of attenuating dietary phosphate restriction on blood ionized calcium concentrations in cats with chronic kidney disease and ionized hypercalcemia
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The effect of attenuating dietary phosphate restriction on blood ionized calcium concentrations in cats with chronic kidney disease and ionized hypercalcemia
Rebecca F. Geddes et al · Oxford University Press · 2021 · ISSN 0891-6640
Abstract Background Hypercalcemia is commonly observed in cats with azotemic chronic kidney disease (CKD). Dietary phosphate restriction is considered standard of care but may contribute to the development of hypercalcem...
LCC TENDOlZldGVyaW5hcnkgbWVkaWNpbmU~Idioma eng
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Beyond Airway Clearance: Specific Antibody Deficiency as a Driver of Refractory Sinopulmonary Disease in Primary Ciliary Dyskinesia
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Beyond Airway Clearance: Specific Antibody Deficiency as a Driver of Refractory Sinopulmonary Disease in Primary Ciliary Dyskinesia
Nathaniel Srikureja, MD et al · Rockefeller University Press · 2026 · ISSN 3065-8993
BackgroundPrimary ciliary dyskinesia (PCD) management relies on mucociliary clearance to prevent bronchiectasis. While humoral immunodeficiencies have been reported in PCD, their clinical significance remains under-defin...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Does concomitant treatment of tributary varicose veins improve the results of standard endovenous thermal ablation of the great or small saphenous trunk? A systematic review and metanalysis
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Does concomitant treatment of tributary varicose veins improve the results of standard endovenous thermal ablation of the great or small saphenous trunk? A systematic review and metanalysis
Pietro Bertini et al · PAGEPress Publications · 2026 · ISSN 2279-7483
The optimal management of tributary varicose veins during Endovenous Thermal Ablation (EVTA) of the saphenous trunk for Chronic Venous Disease (CVD) remains an area of ongoing clinical debate. This study compares the “...
LCC TENDOkRpc2Vhc2VzIG9mIHRoZSBjaXJjdWxhdG9yeSAoQ2FyZGlvdmFzY3VsYXIpIHN5c3RlbQ~~Idioma eng
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The epidemiological trends of multiple sclerosis among women of child-bearing age: a global analysis from 1990 to 2021 and forecasts to 2040
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The epidemiological trends of multiple sclerosis among women of child-bearing age: a global analysis from 1990 to 2021 and forecasts to 2040
Zhuo-lei Cai et al · Frontiers Media S.A · 2026 · ISSN 1664-3224
IntroductionMultiple sclerosis (MS) shows marked female predominance, particularly among women of childbearing age (WCBA, 15–49 years), yet their specific disease burden remains under characterized. Using Global Burden...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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The risk of neoplasms in appendiceal abscess: what emergency surgeons should know
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The risk of neoplasms in appendiceal abscess: what emergency surgeons should know
Giulia Montori et al · Frontiers Media S.A · 2026 · ISSN 2234-943X
IntroductionA subset of patients with acute appendicitis presents with complicated disease characterized by periappendiceal abscess. Although appendiceal neoplasms are rare in uncomplicated appendicitis, recent evidence ...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Clinical characteristics of dogs with food‐responsive protein‐losing enteropathy
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Clinical characteristics of dogs with food‐responsive protein‐losing enteropathy
Noriyuki Nagata et al · Oxford University Press · 2020 · ISSN 0891-6640
Abstract Background In dogs with protein‐losing enteropathy (PLE), data on the clinical characteristics of food‐responsive PLE (FR‐PLE) remain scarce. Objective To determine the clinical characteristics of FR‐PLE...
LCC TENDOlZldGVyaW5hcnkgbWVkaWNpbmU~Idioma eng
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Immune Checkpoint Inhibitor-Induced Thyroidal, Pancreatic, and Pituitary Dysfunction: Diagnostic Challenges in a Cancer Patient
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Immune Checkpoint Inhibitor-Induced Thyroidal, Pancreatic, and Pituitary Dysfunction: Diagnostic Challenges in a Cancer Patient
Sara Gil dos Santos et al · Ordem dos Médicos · 2025 · ISSN 0870-399X
Immune checkpoint inhibitors (ICPIs)-induced endocrine immune-related adverse events (irAEs) are common, can appear concurrently, and can be overlooked due to their nonspecific presentation overlapping with cancer-relate...
LCC LCC:Medicine; TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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A time-adapted risk stratification framework guided by longitudinal post-radiotherapy EBV DNA clearance for high-risk nasopharyngeal carcinoma patients
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A time-adapted risk stratification framework guided by longitudinal post-radiotherapy EBV DNA clearance for high-risk nasopharyngeal carcinoma patients
Ying Li et al · BMC · 2026 · ISSN 1748-717X
Abstract Purpose Patients with nasopharyngeal carcinoma (NPC) exhibiting persistent EBV DNA positivity throughout treatment (a “D-D-D” trajectory) represent a high-risk group with undefined management strategies. Thi...
LCC TENDOk1lZGljYWwgcGh5c2ljcy4gTWVkaWNhbCByYWRpb2xvZ3kuIE51Y2xlYXIgbWVkaWNpbmU~; TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neSIdioma eng
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Age specific associations and component patterns of healthy ageing using propensity score matching analysis
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Age specific associations and component patterns of healthy ageing using propensity score matching analysis
Jed Montayre et al · Springer · 2026 · ISSN 3005-0774
Abstract Background Healthy ageing encompasses maintaining optimal physical, psychological, social, and cognitive well-being across the lifespan. While age-specific needs are widely acknowledged, many studies aggregate a...
LCC LCC:Public aspects of medicineIdioma eng
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Anti-Thyroglobulin Antibodies as a Surrogate Tumor Marker for the Follow-Up of the Differentiated Thyroid Carcinoma: Clinical Implications and Pitfalls
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Anti-Thyroglobulin Antibodies as a Surrogate Tumor Marker for the Follow-Up of the Differentiated Thyroid Carcinoma: Clinical Implications and Pitfalls
Esra Eraslan Aydemir et al · Trakya University · 2026 · ISSN 2146-3123
Antithyroglobulin antibodies (TgAb) are present in 10–25% of patients with differentiated thyroid cancer (DTC) and significantly affect the reliability of serum thyroglobulin (Tg) measurements during follow-up. Beyond ...
LCC LCC:MedicineIdioma eng
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Case Report and retrospective literature analysis of pediatric lower esophageal squamous cell carcinoma: focus on diagnostic challenges and therapeutic strategies
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Case Report and retrospective literature analysis of pediatric lower esophageal squamous cell carcinoma: focus on diagnostic challenges and therapeutic strategies
Jiani Hu et al · Frontiers Media S.A · 2026 · ISSN 2296-2360
Malignant solid tumors of the gastrointestinal tract are clinically rare in children, with malignant solid tumors of the esophagus being particularly uncommon. Clinical reports on esophageal cancer in children are extrem...
LCC TENDOlBlZGlhdHJpY3M~Idioma eng
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Comparative Analysis of Primary Closure, Rhomboid Flap, and Open Technique in Pilonidal Sinus Surgery: A Retrospective Cohort Study
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Comparative Analysis of Primary Closure, Rhomboid Flap, and Open Technique in Pilonidal Sinus Surgery: A Retrospective Cohort Study
Mohamed Sayed et al · Atatürk University · 2026 · ISSN 3062-3308
Objective: Pilonidal sinus disease (PSD) is a common condition in young adults, with multiple surgical options available. The optimal technique remains debated due to trade-offs between recurrence, healing time, and pati...
LCC TENDOlN1cmdlcnk~Idioma eng
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Construction of a risk prediction model for blood pressure abnormality in occupational populations based on longitudinal occupational health surveillance data
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Construction of a risk prediction model for blood pressure abnormality in occupational populations based on longitudinal occupational health surveillance data
Tengxiao SHAN et al · Editorial Committee of Journal of Environmental and Occupational Medicine · 2026 · ISSN 2095-9982
BackgroundThe prevalence of chronic diseases among the Chinese occupational population is rising steadily, with hypertension and diabetes becoming important health concerns. Occupational health examinations (OHE) provide...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~; TENDOlRveGljb2xvZ3kuIFBvaXNvbnM~Idioma eng
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Determinants and clinical consequences of non-adherence to aerosol therapy in adolescents with asthma: a prospective observational study from eastern India
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Determinants and clinical consequences of non-adherence to aerosol therapy in adolescents with asthma: a prospective observational study from eastern India
Debjyoti Roy et al · Manipal College of Medical Sciences, Pokhara · 2026 · ISSN 2467-9100
Background: Adolescents with asthma represent a high-risk group for poor disease control, largely due to suboptimal adherence to inhaled therapy. Despite advances in guideline-directed management, medication non-adherenc...
LCC LCC:MedicineIdioma eng
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Determinants of mortality following intertrochanteric fractures, comorbidities versus reduction quality: retrospective cohort study
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Determinants of mortality following intertrochanteric fractures, comorbidities versus reduction quality: retrospective cohort study
Bugra Kundakci et al · BMC · 2026 · ISSN 1749-799X
Abstract Background Intertrochanteric femoral fractures are common in the elderly population and are associated with substantial mortality. While fracture reduction quality is known to influence mechanical outcomes, its ...
LCC TENDOk9ydGhvcGVkaWMgc3VyZ2VyeQ~~; LCC:Diseases of the musculoskeletal systemIdioma eng
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