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Abstract Background Paediatric cancer survival rates continue to improve with overall long-term survival now over 80%. A significant proportion of conventional and novel cancer therapies have cardiovascular toxicities wh...

BackgroundOsteosarcoma (OS) is the most common primary malignant bone tumour in adolescents, and pulmonary metastasis remains the leading cause of death. In skeletally immature patients, the avascular physis is considere...

Abstract Background In Pakistan, over 10,000 children are diagnosed with cancer annually, with leukemia being the most common. These cases present challenges in symptom management, prognosis, and caregiver burden. Despit...

The treatment of paediatric low-grade gliomas has been previously controversial as to whether upfront surgery or a conservative approach should be utilised, with a recent paradigm shift favouring biopsy or resection, if ...

Materias / palabras clave: triple-negative breast cancer; neoadjuvant chemotherapy; pathological complete response; carboplatin

Materias / palabras clave: brain tumors; epidemiology; survival

Materias / palabras clave: malignant phyllodes tumor; progression-free survival; overall survival; ifosfamide + doxorubicin (IA)

Materias / palabras clave: multiple primary malignancies; synchronous; metachronous; survival; risk factors; retrospective observational studies

Methotrexate (MTX) is a crucial chemotherapy drug often associated with various adverse effects. Predicting the frequency and severity of these side effects poses a challenge, as they can vary significantly among individ...

Paraneoplastic syndromes (PNS) are triggered by an altered immune system response to a neoplasm. The symptoms of PNS usually precede malignancy making its diagnosis difficult. They are rarely associated with breast cance...