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ABSTRACT Background and Aims Preterm neonates are at higher risk of cumulative procedural pain at a crucial point in brain development. Several procedures performed in neonatal intensive care units (NICUs) have ineffecti...

ABSTRACT Background and Aims Effective pain management remains a critical component of emergency care. However, patient‐related beliefs and misconceptions about pain medication can pose significant barriers to adequate...

BackgroundHip fractures in older adults are costly and often fatal. Cognitive impairment (CI) complicates pain assessment, raises delirium risk, and hinders early mobilization and rehabilitation. This review synthesizes ...

Background: Chronic kidney disease (CKD) is a progressive condition characterized by structural and functional impairments in the kidneys, affecting around 10–15% of the global population. Kidney transplantation from l...

Introduction. The 2025 FDA approval of suzetrigine (Journavx) ended a 25-year stagnation in analgesic development. This introduced a paradigm shift in pain management. As a first-in-class, highly selective NaV1.8 sodium...

James S Cho,1,2 Julia Zhu,2 Pritesh Topiwala,1,2 David Hao1,2 1Department of Anesthesiology, Mass General Brigham, Boston, MA, USA; 2Harvard Medical School, Boston, MA, USACorrespondence: David Hao, Department of Anesthe...

The current study focuses on the creation and evaluation of a topical gel that contains the nonsteroidal anti-inflammatory medication (NSAID) naproxen, a pain reliever. Carbopol and propylene glycol were used as gelling ...

Aafreen Aafreen,1 Abdur Raheem Khan,2 Ausaf Ahmad,3 Yousef M Alshehre,1 Mohammed M Alshehri,4 Mohammad Abu Shaphe,4 Monira I Aldhahi5 1Department of Health Rehabilitation Sciences, Faculty of Applied Medical Sciences, Un...

BackgroundThe adverse impacts of chronic pain extend far beyond the physical sensation itself. Chronic pain, an age-related condition, exacerbates geriatric disease burden and drives a central sensitivity-neuropsychiatri...

Background: Diaphragm excursion is a prevalent condition often overlooked in relation to postpartum low back pain. Diaphragmatic function plays a vital but often underrecognized role in postpartum low back pain (LBP). Th...

Abstract Background Port-A-Cath needle insertion in pediatric chemotherapy is often painful and stressing. Distraction is a non-pharmacological method of pain management in invasive procedures in children. The purpose of...

Chronic pain is a significant global health burden often resistant to conventional analgesics. Evidence implicates that mitochondrial dysfunction is not only a cellular consequence of injury, but also a fundamental drive...

Hui Wu,1– 4,* Meiyan Zhou,2,* Songtao Liu,2,* Yu Qi,2 Fan Zhou,1– 4 Liwei Wang,1,2 Conghai Fan1,3,4 1College of Anesthesiology, Xuzhou Medical University, Xuzhou, Jiangsu, People’s Republic ...

Odontectomy is a surgical procedure to extract impacted teeth and also commonly performed to address dental and oral health issues. One symptom observed prior to the procedure is anxiety that may cause patients to avoid ...

This review evaluates the efficacy of PRP in treating peripheral neuropathies, including carpal tunnel syndrome (CTS), ulnar neuritis, common peroneal nerve palsy, and piriformis syndrome.Studies were identified through ...

Vadim Tashlykov,1 Ruth Gur,2 Gabriel Ricardo Lichtenstein,2 Itay Goor-Aryeh,2 Evgeni Brotfain3 1Department of Anesthesiology, Pain Clinic, Samson University Medical Center, Public Hospital Assuta, Ashdod, Israel; 2Depart...

The etiology of temporomandibular disorders (TMDs) is multifactorial and often associated with biopsychosocial factors. Stress, anxiety, and depression contribute to the psychological conditions that may accompany TMD. T...

Background: Fibromyalgia is associated with chronic pain, affective burden, and limited response to pharmacological treatment alone; emerging evidence suggests psychological interventions, including Eye Movement Desensit...

BackgroundPatients with rheumatoid arthritis (RA) and concomitant fibromyalgia (FM) frequently experience severe, refractory pain, elevated disease activity scores, and substantial psychological distress. Conventional tr...

Introduction:Orthopedic and musculoskeletal pain is a leading cause of disability worldwide, and many patients continue to experience suboptimal relief despite advances in pharmacological and physical therapies. Magnetic...

ABSTRACT Background University students are susceptible to low back pain (LBP) because of their predisposition to various factors that have been previously linked to the increased risk of LBP among other populations. The...

BackgroundChronic low back pain (CLBP), with or without radicular pain (RP), is a major cause of disability and reduced quality of life. Psychological comorbidities such as depression, anxiety, and chronic pain disorder ...

Objective Patient autonomy has great importance for a valid informed consent in clinical practice. Our objectives were to quantify thedomains of patient autonomy and to evaluate the variables that can affect patient aut...

Purpose of research. The aim of this study was to evaluate the roles of vitamin D and physical activity in the management of endometriosis, with particular emphasis on their effects on pain reduction, physical function, ...