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Artificial pancreas (AP) algorithms can be divided into single-hormone (SH) and dual-hormone (DH). SH algorithms regulate glycemia using insulin as their control input. On the other hand, DH algorithms also use glucagon ...

"The first two studies of an artificial pancreas (AP) system carried out in Latin America took place in 2016 (phase 1) and 2017 (phase 2). They evaluated a hybrid algorithm from the University of Virginia (UVA) and the a...

"The purpose of this work is to compute a linear parameter-varying (LPV) model set that describes the insulin-glucose dynamics in type 1 diabetes (T1D). This set includes a nominal LPV model and dynamic uncertainty and i...

OBJECTIVE: The aim of our study was to compare the efficacy and safety of pancreas transplantation concomitant with renal transplantation (SPKT) or following renal transplantation (PAKT) and the exocrine anastomosis meth...

Serine proteases have wide application in leather, food, meat and soap powder industries, among others. There are a lot of methodologies to obtain them in large quantities but most of them are expensive or contaminating....

Objective: To develop an artificial intelligence (AI) driven plan tradeoff decision making assistant for radiation oncologists. Methods: A user interface (UI) was developed to integrate the assistant with the treatment p...

BackgroundSolid pseudopapillary tumors (SPTs) of the pancreas are rare, low-grade malignancies that generally have favorable outcomes when diagnosed at an early stage and can be resected. However, treatment options for p...

Background Renal replacement therapies can be life‐saving for dogs with severe acute kidney injury (AKI), however, comorbidities including pancreatitis might affect outcome. Hypothesis/Objectives To investigate the pre...

The adsorption of commercial trypsin (Try) onto epichlorohydrin cross-linked alginate–guar gum matrix has been studied at equilibrium in batch and in fixed bed column. Experiments were conducted to study the effect of ...

Acute pancreatitis (AP) urgently requires new therapeutic strategies. Here, we developed a maltose-alginate synbiotic microcapsule (AM-AR113) for intestinal delivery of Lactiplantibacillus plantarum AR113 and evaluated i...

OBJECTIVE: Oxidative stress is responsible for some important complications of diabetes mellitus. Zofenopril, which has an antioxidant effect, may decrease the oxidative stress of the diabetic microenvironment. The aim o...

The purpose of this article is to present a non-hybrid fully closed-loop controller for the Artificial Pancreas (AP) problem focused on long-term clinical trials and home-use applications. It includes physical activity (...

"In this work, a low-order model designed for glucose regulation in Type 1 Diabetes Mellitus (T1DM) is obtained from the UVA/Padova metabolic simulator. It captures not only the nonlinear behavior of the glucose-insul...

A pesar de que la ozonoterapia se ha utilizado con éxito en la terapia con efectos beneficiosos, se han realizado pocos estudios bioquímicos o farmacodinámicos dirigidos al estudio de su mecanismo de acción. Hemos de...

"Keeping the blood glucose levels within the safe range during meals and exercise still represents a major hurdle not only for patients with type 1 diabetes (T1D), but also for Artificial Pancreas (AP) systems. One of th...

Objective: In contrast to penetrating trauma, blunt pancreatic trauma poses numerous challenges for treating surgeons, mainly due to the different clinical manifestations. Materials and methods: This is a retrospective o...

"En este trabajo se presenta la experiencia argentina en el problema de regulación de los niveles de glucosa en sangre para pacientes con Diabetes Mellitus Tipo 1 (insulino-dependientes), denominado Páncreas Artificial...

The peroxisome proliferator-activated receptors (PPARs), including PPAR-α, PPAR-β/δ, and PPAR-γ, are nuclear receptors that play critical roles in regulating metabolism and inflammation. While PPARs have been extensi...

Abstract Background Pancreatitis in cats, although commonly diagnosed, still presents many diagnostic and management challenges. Objective To summarize the current literature as it relates to etiology, pathogenesis, diag...

"A new approach to automatically regulate the glucose level in type 1 diabetes is presented in this work. This is the so-called Automatic Regulation of Glucose (ARG) algorithm, which is based on a switched Linear Quadrat...

Background: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease with a survival rate of 4–6 months from diagnosis. PDAC is the fourth leading cause of cancer-related death in the Western world, with a mort...

In the non-obese diabetic (NOD) mouse, a spontaneous model of type 1 diabetes (T1D), recent evidence suggests that Schwann cells (Scs) and neurons surrounding insulin-producing β cells of the islets of Langerhans are de...

"Time-varying dynamics is one of the main issues for achieving safe blood glucose control in type I diabetes mellitus (TI DM) patients. In addition, the typical disturbances considered for controller design are meals, wh...

Some degree of glucose intolerance develops in all patients with chronic renal failure. The present study was designed to investigate the effect of Parathyroid hormone (PTH) on peripheral glucose metabolism of patients w...