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BackgroundX-linked hyper IgM syndrome (XHIGM) is a rare primary immunodeficiency (PID) caused by pathogenic variants in the CD40 ligand (CD40LG) gene, resulting in defective immunoglobulin class-switch recombination, cau...

Abstract Objective To investigate the clinical efficacy and safety of pediatric tuina combined with glycerin enema for pediatric intussusception, in order to reduce unnecessary invasive procedures, enhance the safety of ...

Objective: To compare digital impression with the traditional method in 6-year-old children, evaluating preference, comfort, and the time required for each technique. Material and Methods: A randomized, controlled, singl...

BackgroundActivated phosphoinositide 3-kinase syndrome (APDS) is a rare inborn error of immunity with an autosomal-dominant inheritance pattern that leads to immune dysregulation. Presently, the natural history of diseas...

Purpose Despite knowing that adolescents with disabilities face substantial barriers transitioning from pediatric to adult health care, little is known about how pediatricians experience transition-related tasks for thei...

IntroductionUnderstanding the progression of dental caries in children, characterized by transitions between distinct health states, may benefit the development of prevention and disease modeling frameworks. This systema...

Abstract Introduction Respiratory syncytial virus (RSV) is the leading cause of respiratory infections and hospitalization among infants and a major burden on pediatric emergency department (EDs). Nirsevimab has recently...

Abstract Background and Objective Children with rheumatic diseases experience social determinants of health that influence access to care and outcomes, yet data in pediatric rheumatology are limited. We aimed to characte...

Artificial intelligence (AI) presents a transformative opportunity for pediatric healthcare, promising advancements in early diagnosis, personalized treatment, and operational efficiency. However, the unique developmenta...

The coronavirus disease 2019 (COVID-19) has introduced new impediments to delivering and accessing dental care. In light of the COVID-19 pandemic experience, research into anticipatory measures for pediatric dental care ...

ObjectivesSince its inception in 2017, China’s National Drug Price Negotiation (NDPN) has served as a crucial mechanism for the strategic procurement of innovative medicines, with pediatric medicines representing a key...

Abstract Background The emergence of tmexCD-toprJ, a plasmid-mediated resistance-nodulation-division efflux pump gene cluster conferring resistance to tigecycline, poses a critical public health threat. While its prevale...

BackgroundTreatment of childhood cancer is associated with a substantial risk of life-threatening complications that may require admission to a pediatric intensive care unit (PICU). Data describing clinical characteristi...

Abstract Background Chemotherapy induced peripheral neuropathy (CIPN) is a symptom commonly reported by pediatric oncology patients who receive neurotoxicity agents. Early identification is imperative for the interventio...

Pediatric cancer treatment causes adverse repercussions to the family, since it establishes changes in caregiving practices and routine adaptations. Understanding how pediatric caregivers cope with such challenges is a r...

Pediatric cancer poses a major health challenge globally, especially in low-middle-income countries like Indonesia. The survival rate of pediatric cancer in many high-income countries (HICs) reaches 90%, while it only ra...

Background: Community Acquired Pneumonia (CAP) is a common cause of pediatric hospitalization and remains a significant contributor to morbidity and healthcare burden globally. Prolonged hospital stays can complicate out...

IntroductionDental caries is a prevalent childhood condition with significant health and economic consequences. Disease management techniques, such as silver diamine fluoride (SDF) and sealants, have emerged as alternati...

Background/Aim: Improper positioning of the patient reduces the diagnostic quality of panoramic radiographs. It is important to perfect the panoramic patient positioning technique to avoid unnecessary repeat exposures es...

Saliva as a microfluidic system offers numerous advantages for both general and oral health diagnostic and therapeutic procedures since its assembly is quick, stress-free, inexpensive and non-invasive. Moreover, saliva i...

This article describes the foundation of ‘Pediatric Nephrology’ in Turkey including the fi rst steps in the international arena, the achievements in institutionalisation of services and training of pediatricians, a...

With over 54,000 people affected, cystic fibrosis is one of the most common rare diseases in Europe. As life expectancy of this disease has steadily increased in recent years, the transition from pediatric to adult care ...

ABSTRACT Background and Aim Tonsillectomy is one of the most commonly performed surgical procedures on children. Indications for tonsillectomy include recurrent tonsillitis, obstructive sleep apnea, and peritonsillar abs...

To explore the benefits and drawbacks of pediatric hospitalization of adolescents with anorexia nervosa prior to psychiatric hospitalization.