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BackgroundDown syndrome (DS) is associated with chronic hyperactivation of interferon signaling and downstream Janus kinase (JAK) and STAT pathways, contributing to increased susceptibility to autoimmunity, autoinflammat...

Abstract Objective “One-stop” interventional therapy for non-valvular atrial fibrillation (NVAF) traditionally relies on transesophageal echocardiography (TEE) guidance, which carries limitations including anesthe...

During the golden-time phase of urban disasters, emergency response systems must issue timely directives that remain compliant with jurisdictional policies and regulations, even when early human reports precede reliable ...

Background: The release of micro- and nanoplastics (MNPs) from tea bags during brewing is a significant, recently identified source of potential human exposure. This systematic review collected global research published ...

OBJECTIVE: Type 2 diabetes mellitus (T2D) is a chronic metabolic disorder requiring effective management. Ipragliflozin (SGLT-2 inhibitor) and sitagliptin (DPP-4 inhibitor) are commonly used treatments with distinct mech...

ObjectiveTo evaluate the efficacy and safety of skull base-peripheral (SBP) acupuncture in patients with post-stroke cognitive impairment (PSCI).MethodsWe searched eight Chinese and English databases from inception to Ju...

BackgroundStem cell therapy holds considerable potential for treating dry eye syndrome, though it has yet to receive clinical approval.AimThis paper systematically quantifies the efficacy and safety of stem cell-based th...

Phα1β, a peptide toxin purified from Phoneutria nigriventer spider venom, has a dual antinociceptive effect, inhibiting high-voltage-activated calcium channels and antagonising the TRPA1 receptor that differentiates it...

Background/Aim Second-generation immunomodulating drugs for inflammatory dermatoses have expanded over the past decades. Contraindications and special warnings must be considered before starting any treatment, but identi...

Introduction. Myopia is one of the important causes of visual impairment worldwide. The two most common refractive surgeries for myopia treatment are LASIK (Laser-Assisted In-Situ Keratomileusis) and PRK (Photorefractive...

Abstract Background Insufficient breast milk production affects 35–90% of lactating mothers globally, representing a critical barrier to WHO exclusive breastfeeding targets. Although Moringa oleifera has traditional ga...

BackgroundEarly and effective intervention is crucial in the management of acute ischemic stroke (AIS) without large- or medium-vessel occlusion (non-LVO/MVO), which accounts for approximately 60–70% of all AIS cases. ...

Abstract Background Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are widely used for the management of type 2 diabetes and obesity, yet their long-term cardiovascular effects in high-risk populations continue to ...

ABSTRACT Background Hereditary transthyretin‐mediated amyloidosis (hATTR) is a disorder that affects several body systems and can result in life‐threatening conditions like cardiomyopathy and polyneuropathy. For trea...

Abstract Background Diabetic Foot Ulcers (DFUs) represent a global healthcare challenge, imposing substantial socioeconomic burdens due to their increasing incidence and associated mortality. This study evaluates the eff...

BackgroundMigraine is a common neurological disorder that substantially affects patients’ quality of life. Chinese botanical drug decoctions are used in migraine management; however, the comparative efficacy and safety...

Abstract Contractor-related deficiencies remain a critical challenge in workplace health and safety management within high-risk industries, particularly in the oil and gas sector, where heterogeneous safety practices and...

BackgroundThere is growing evidence that workplace violence (WPV) including physical, verbal, psychological, racial and sexual violence against healthcare workers (HCW) is a globally increasing burden, with serious negat...

Aim: This study was conducted to examine postgraduate theses related to patient safety in children in the field of nursing in Türkiye. Method: This systemetic review was conducted by searching the Higher Education Counc...

Huayu Chen,1 Xiaowen Yang,2 Jifang Peng,3 Xianrong Xu,4 Yaping Li,1 Zirong Tong,5 Chunhong Gao5 1Department of Neurosurgery, First Affiliated Hospital with Nanjing Medical University Junior Nurse, Nanjing, Jiangsu, 21002...

Power electronic systems in autonomous vehicles and mission-critical applications are highly susceptible to overheating due to operational inefficiencies. These systems often rely on liquid cooling loops to maintain safe...

BackgroundYupingfeng Powder (YPF), a classical Chinese herbal formula composed of Astragalus membranaceus, Atractylodes macrocephala, and Saposhnikovia divaricata, has demonstrated potential efficacy in the treatment of ...

Abstract Food safety is a critical public health and economic issue in Afghanistan, where regulatory frameworks are evolving in response to complex political, social, and infrastructural challenges. This study examines t...

Abstract Background Safe anesthesia is fundamental to safe surgery and depends on facility readiness, team behaviors, and consistent adherence to safety standards such as the World Health Organization (WHO) Surgical Safe...