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Abstract Enhanced comfort and effective sedation are essential for mechanically ventilated patients, particularly in the ICU. This study evaluates the safety and effectiveness of remimazolam, a novel ultra-short-acting b...

Abstract Background A standardized protocol for electroencephalography (EEG) under standing sedation for the investigation of epilepsy in foals is needed. Hypothesis/Objectives To evaluate a modified standardized EEG pro...

BackgroundPulsed dye laser (PDL) therapy is the gold standard for treating port-wine stains (PWS) in children but frequently requires procedural analgosedation due to pain and the need for immobility. The optimal sedativ...

Abstract Background Atlantoaxial (AA) cerebrospinal fluid (CSF) collection in standing horses utilizes the controlled narcotic morphine, thereby limiting feasibility in field practice settings. Objectives To compare AA C...

ObjectiveThe study aimed to assess the effects of resting energy expenditure (REE) on critically ill individuals requiring mechanical ventilation with different degrees of sedation.DesignA prospective self-controlled stu...

BackgroundDelirium and poor clinical prognoses are prevalent among ICU patients, particularly those requiring mechanical ventilation. While sedation is a cornerstone of intensive care, the impact of its depth remains con...

Abstract Background Electroencephalography (EEG) recording protocols have been standardized for humans. Although the utilization of techniques in veterinary medicine is increasing, a standard protocol has not yet been es...

Kai Wang,1,2,* Shuhan Zhang,1,* Zhaoyu Lv,1,* Wei Chen,1 Yonghua Li1 1Department of Anesthesiology, Second Affiliated Hospital of Naval Medical University (Shanghai Changzheng Hospital), Shanghai,...

Background Dog breeds with the ABCB1‐1Δ mutation have substantially truncated nonfunctional P‐glycoprotein. Dogs homozygous for this mutation (mut/mut) are susceptible to the toxic adverse effects of ivermectin, lop...

Gaofei Fan, Mingming Han, Shudong Wang, Min Zhang, Fang Kang, Juan Li Department of Anesthesiology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of C...

Clinical and behavioral effects of intravenous injection of romifidine (60mcg/kg) or amitraz (0.4mg/kg) were compared in six horses, over 120 min. Romifidine caused head ptosis (HP), reduced respiratory rate (RR) and ile...

Abstract Background Gabapentin is often administered PO for preappointment or in‐hospital anxiolysis in cats. A previous study reported mild changes on the neurologic examination after administration. Objectives Invest...

Abstract Background Working dogs exposed to narcotics might require reversal in the field. Objective To explore the pharmacokinetic and pharmacodynamic effects of naloxone administered intramuscularly (IM) or intranasall...

Os anestésicos são importantes na piscicultura para reduzir o estresse e a mortalidade no manejo. Este trabalho tem como objetivo determinar a eficácia do mentol para tambaqui durante o manejo. Na primeira série de t...

RESUMO A utilização de protocolos de sedação como auxílio na contenção de felinos para realização de coletas de sangue é de grande importância, porém a utilização de alguns fármacos pode alterar resultados...

Combined diquat and paraquat poisoning is a rare but clinically significant form of poisoning, associated with severe oxidative stress and multiorgan failure. Historical case series have reported high case fatality, part...

Abstract Bronchopulmonary dysplasia (BPD) is a common complication among preterm neonates, with portable X-ray imaging serving as the standard diagnostic modality in neonatal intensive care units (NICUs). However, lung m...

Background: Post-operative pain still remains a major issue even with modern surgical techniques. Opioids and non-steroidal anti-inflammatory drugs cause many side effects so clinicians try to use opioid-sparing drugs. P...

Lloyd M Halpern,1 Zackary Correll,2 De-An Zhang,3 Clark J Kogan,4 Kirk A Ryan,5 Ted Sousa6 1Department of Anesthesia, Shriners Children’s Hospital, Spokane, WA, USA; 2Department of Medicine, University of Washington Sc...

Abstract Background Ciprofol is increasingly used for endoscopic sedation due to its reduced injection pain, but evidence regarding its safety when combined with etomidate in elderly patients remains limited. This study ...

Abstract Background Trigeminal‐mediated headshaking is a neuropathic facial pain condition in horses. No treatment has been entirely successful. Repetitive transcranial magnetic stimulation (rTMS) is used in human medi...

Dongjing Shi, Xuan Liang, Chunhua Xi, Chunming Pei, Guyan Wang Department of Anesthesiology, Beijing Tongren Hospital, Capital Medical University, Beijing, People’s Republic of ChinaCorrespondence: Guyan Wang, Departme...

Abstract Background Radical prostatectomy (RP) is associated with moderate to severe postoperative dynamic pain. In this study, we aimed to evaluate the effect of erector spinae plane block (ESPB) on postoperative Qualit...

Benzodiazepines are the most widely prescribed class of psychoactive drugs in current therapeutic use, despite the important unwanted side effects that they produce, such as sedation, myorelaxation, ataxia, amnesia, and ...