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Abstract Epilepsy is a common neurological disorder giving rise to both recurrent and spontaneous seizures as well as additional neurological comorbidities. In approximately 30% of patients, seizures are not ameliorated ...

Background: Febrile seizures are common in children under five, with simple seizures being brief and harmless, while complex seizures have higher risks. Incidence and recurrence are influenced by age, family history, imm...

Abstract Objective: To report a case of post-electroconvulsive therapy spontaneous seizures in a patient medicated with sertraline, bupropion and risperidone. Case description: A 53-year-old woman with recurrent majo...

Purpose: Previous studies from a few countries have reported semiological differences in younger children compared with adolescents or adults with psychogenic nonepileptic seizures (PNESs). This study tested the hypothes...

Introduction: Febrile Seizures (FS) are common in early childhood, and bedside biochemical testing is frequently ordered despite mixed evidence regarding underlying biochemical drivers. Clarifying which analytes truly di...

Abstract Background Neonatal seizures are sudden, abnormal brain activities that occur during the neonatal period, are the most common neurological emergencies in newborns, and are associated with high morbidity and mort...

ObjectivePatients seen for uncontrolled seizures in a Pediatric Emergency Department (ED) often undergo tracheal intubation (TI). We looked at factors associated with TI in children in a safety net hospital.MethodsThis w...

Animal models of epilepsy are critical in drug development and therapeutic testing. However, dominant methods for evaluating epilepsy treatments face a tradeoff between higher throughput and etiological relevance. Screen...

Objectives: Psychiatric disorders are frequently found in both patients with PNES and DRE, making the differential diagnosis even more complex. The aim of this study was to analyze and compare psychiatric aspects and the...

Abstract Objective To accurately predict neurological outcomes among survivors after cardiac arrest (CA), we aim to analyze the experimental data of epileptiform electroencephalography (EEG) in CA survivors to explore th...

Abstract Background A standardized protocol for electroencephalography (EEG) under standing sedation for the investigation of epilepsy in foals is needed. Hypothesis/Objectives To evaluate a modified standardized EEG pro...

Abstract Background Approximately 30% of dogs with idiopathic epilepsy (IE) are drug‐resistant. Recent studies have suggested cannabidiol (CBD) may be an effective anticonvulsant in dogs with IE. Objective To evaluate ...

Abstract Background Clinical signs and their progression in Beagles with Lafora disease are poorly described. Objectives To describe clinical signs in Beagles with Lafora disease. Animals Twenty‐eight Beagles with Lafo...

Objective To investigate the alleviating effect of jujuboside B (JuB) on acute epilepsy in mice and its protective effect on hippocampal neurons. MethodsAn in vitro epilepsy model was established by stimulating primary h...

Las crisis atónicas focales son poco reconocidas como fenómenos ictales, pueden corresponder tanto a una epilepsia generalizada como a una epilepsia focal. Las áreas del cerebro implicadas en la gestión de este tipo ...

BackgroundInfantile epileptic spasms syndrome (IESS) is a severe age-specific epileptic encephalopathy with unclear pathogenesis, and neuroinflammation is involved in its progression. The HMGB1-TLR4 signaling pathway, a ...

Abstract Background Brain imaging suggests the involvement of the limbic system, particularly the cingulate gyrus (GC), in dogs with idiopathic epilepsy (IE). Hypothesis A correlation exists between the side of intericta...

Lambotte Syndrome (LS) comprises Intrauterine Growth Retardation (IUGR), cerebral dysgenesis, microcephaly, and early mortality. Dandy-Walker Syndrome (DWS) is characterised by a triad of hypoplastic cerebellar vermis, c...

Renal involvement in systemic lupus erythematosus is a frequent and serious complication that significantly increases morbidity and mortality. Despite all studies and usage of new drugs, treatment of lupus nephritis cont...

Uremic encephalopathy is a common complication of uremia. Altered consciousness, seizures, visual disturbances, hemiparesies, multifocal clonus may be observed. Extrapyramidal symptoms such as bradykinesia and dysarthria...

Neonatal seizures are most commonly attributed to hypoxic-ischaemic injury, metabolic abnormalities, or central nervous system infections; however, an increasing proportion of cases are recognised to have an underlying g...

Children with epilepsy frequently experience a range of significant comorbidities beyond seizures, such as motor dysfunction, cognitive impairment, and neurodevelopmental delays. In some cases, these comorbidities contri...

Epilepsy is a common neurological disorder which affects 50 million people worldwide. Patients with epilepsy may present cognitive deficits and psychological impairment. Currently, 30% of patients fail to respond to any ...

Dear EditorPhosphomannomutase-2 deficiency-congenital disorder of glycosylation (PMM2-CDG), congenital disorder of glycosylation type-Ia or Jaeken syndrome (MIM #601785) is an autosomal recessive inherited condition of a...