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Background and objectivesPostoperative recurrence after percutaneous transforaminal endoscopic decompression (PTED) for degenerative lumbar spinal stenosis (DLSS) remains a clinically relevant challenge, complicating pre...

ABSTRACT Spinal cord injury (SCI), which is a severe complication of spinal fractures, often causes the dysfunction of the spinal cord and results in sensory and motor abnormalities. Current clinical treatments—includi...

Background: The rehabilitation experience can influence the transition back to home and community life. With impending National Health Insurance reform and limited rehabilitation guidelines in South Africa, there is a n...

Abstract Amaranthus spinosus L. is a member of the Amaranthaceae family, commonly known as the spiny amaranth, or spiny pigweed. It is native to the tropical Americas, but is present on most continents as an introduced s...

Abstract Background In the Netherlands, approximately 20,000 older adults sustain a hip fracture every year. Most of these patients are frail, institutionalised, have limited postoperative mobility and a high mortality r...

Abstract Two-dimensional ferromagnetic materials hold great promise for advancing low-power, high-integrated spintronic devices due to their atomic flat surfaces and versatile interfacial modulation. However, achieving a...

Background Challenges in accessing comprehensive sexual and reproductive health (SRH) information and care leave many individuals with spina bifida (SB) vulnerable to unmet SRH needs, risking unfulfilling sexual experien...

We report an extremely rare X-ray active blue straggler star (BSS) in Collinder 261, undergoing ongoing Roche-lobe overflow in a semidetached binary in an Algol-type configuration with an orbital period of P _orb  ∼ ...

The treatment of paediatric low-grade gliomas has been previously controversial as to whether upfront surgery or a conservative approach should be utilised, with a recent paradigm shift favouring biopsy or resection, if ...

Abstract Axial spondyloarthritis (AxSpA) is a chronic inflammatory condition of the spine and sacroiliac joints, associated with a considerable functional and psychosocial burden. This study aimed to investigate the inte...

Abstract Background Early detection of renal involvement in ANCA-associated vasculitis (AAV) is crucial, as functional changes often precede anatomical damage. Current diagnostic standards, such as the measurement of ser...

Background: Scapulohumeral rhythm (SHR) is a key metric for evaluating shoulder joint function. Current established methods of SHR analysis involve 3-dimensional (3D) to 2-dimensional (2D) registration, which requires si...

Depression represents a significant global public health problem, negatively affecting patients’ quality of life and social functioning. Despite the increasing availability of effective pharmacological and psychotherap...

ABSTRACT: Background: Anoikis plays an important role in cancer metastasis. Nevertheless, research that focuses on the prognostic values of anoikis-related genes (ARGs) in oral squamous cell carcinoma (OSCC) is still sc...

Abstract Intervertebral disc (IVD) degenerative disease is a prevalent and debilitating spinal disease. Current treatments only focus on symptomatic relief but fail to halt disease progression or restore the native biome...

Post-translational modifications (PTMs) play pivotal roles in ovarian cancer pathogenesis, with poly(ADP-ribosyl)ation (PARylation) serving as a key regulator of DNA repair, immune evasion, and therapeutic resistance. Be...

Bisphenols (BPs), ubiquitous in food packaging, medical, and personal care products, are pervasive environmental contaminants. As bisphenol A (BPA) is increasingly replaced by its alternatives, the risk of mixed exposure...

Chronic pain affects hundreds of millions worldwide, yet current treatments—from NSAIDs to opioids—fall short and bring unwanted side effects. Neuroinflammation drives bidirectional glial-neuronal communication, a co...

Abstract Medicine is evolving beyond therapy largely predicated on anatomical information and towards incorporating patient-specific molecular biomarkers of disease for more accurate diagnosis and effective treatment. Th...