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Abstract Background Gut microbiota dysbiosis is a key pathological feature closely linked to metabolic disorders and neuroinflammation. It is typically characterized by reduced levels of beneficial microbial metabolites,...

Abstract Background Gait impairments following chronic neurological conditions, such as spinal cord injury (SCI), represent a major challenge for rehabilitation, with limited options to sustain functional recovery and pa...

ABSTRACT The biportal endoscopic technique, known as unilateral biportal endoscopy (UBE), has emerged as an effective minimally invasive approach for managing various spinal disorders. This report presents the first docu...

Abstract Background To evaluate the efficacy of an Internet-based Cognitive Behavioral Therapy (ICBT) program in improving kinesiophobia, exercise adherence, pain intensity, lumbar function, and spinal alignment paramete...

Abstract Background The theoretical Roussouly classification describes sagittal spinal profiles based on pelvic morphology. As most reference data originate from Caucasian populations, its applicability to Hispanic popul...

Circadian rhythms are essential for maintaining intervertebral disc (IDD) homeostasis and regulate cellular metabolism, mechanical responses, and therapeutic efficacy. Core clock genes, especially CLOCK and BMAL1, have c...

Abstract Background Chronic low back pain (CLBP) is a common musculoskeletal symptom associated with spinal disorders, impairing quality of life while imposing significant medical and socioeconomic burdens. Traditional l...

Abstract Background Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune central nervous system disorder mainly associated with aquaporin-4 antibodies. While it primarily affects the optic nerves and spinal co...

IntroductionSouth American camelids (SACs) and dromedaries presenting with neurological abnormalities are increasingly common in veterinary practice. Advanced diagnostic imaging techniques, such as computed tomography (C...

Depression represents a significant global public health problem, negatively affecting patients’ quality of life and social functioning. Despite the increasing availability of effective pharmacological and psychotherap...

IntroductionThe immune system is recognized as participating in the pathophysiology of psychiatric disease and there is renewed interest in identifying biomarkers of this immune activation. MethodsWe measured serum and c...

In this study, we analyzed peripheral nerve anomalies in 15 anuran species spanning multiple developmental stages. Anatomical examinations focused on both the central nervous system—including the olfactory bulbs, telen...

Neurological disorders such as post-stroke hemiplegia, spinal cord injury, and Parkinson disease represent a major global health burden. Brain-computer interface (BCI), which creates direct communication pathways between...

Abstract Background Ankylosing spondylitis (AS) is a chronic inflammatory disorder marked by spinal ossification that leads to progressive thoracolumbar kyphosis (TLK). We previously introduced vertebral body compression...