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BackgroundSevere oral complications during and after antineoplastic therapies, such as mucositis, fungal, viral, and bacterial infections, xerostomia, dysphagia, and jaw osteonecrosis, significantly impair oral health an...

ObjectiveTo evaluate the association between adherence to adjuvant endocrine therapy and overall survival as well as breast cancer–specific survival in patients with hormone receptor–positive breast cancer, to charac...

Background: Guidelines do not recommend routine glycoprotein IIb/IIIa inhibitors (GPIs), reserving them for high thrombotic-risk or bailout cases. Most acute coronary syndrome (ACS) patients undergoing percutaneous coron...

We report a case of a 51-y-old female presenting with synchronous double primary malignancies: advanced endometrial cancer and early-stage lung cancer. One year a post-chemotherapy withdrawal due to toxicity, she develop...

Abstract Background Managing the simultaneous treatment of HIV/AIDS and tuberculosis (TB) increases the risk of adverse reactions, drug interactions, and challenges to treatment adherence. To address these complexities, ...

Abstract Background This systematic review and meta-analysis evaluates the safety and efficacy of emerging prostate-specific membrane antigen (PSMA) radioligand therapy (RLT) agents used beyond [¹⁷⁷Lu]Lu-PSMA in met...

Photodynamic inactivation (PDI) combines the use of photosensitizers with visible light to produce reactive oxygen species that effectively eliminate pathogens. To investigate the impact of near- infrared therapy (NIRT) ...

The present study was aim to evaluate the acceptability and preliminary effectiveness of a mobile-health application, CALMA, based on dialectical behavioral therapy skills. CALMA was proposed as an adjunct to therapy for...

Abstract Background Formulating sophisticated fluid therapy plans can be complicated and time consuming. Consequently, veterinarians in the field who lack experience, time, or confidence may formulate suboptimal fluid th...

IntroductionSystemic juvenile idiopathic arthritis-associated lung disease (sJIA-LD) is a rare, potentially fatal complication of sJIA, often accompanied by pulmonary hypertension (PHTN) and macrophage activation syndrom...

Objective: To compare clinical and structural outcomes of combination therapy (anti-VEGF + PDT) versus anti-VEGF monotherapy in patients with pachychoroid neovasculopathy (PNV) during 12-month follow-up. Materials and Me...

Abstract Background Basketball is one of the most popular sports. In basketball, the energy demand from several combinations of aerobic and anaerobic sports in which athletes need physical fitness, explosive power, agili...

Introduction. Alopecia areata (AA) is a chronic inflammatory disease that involves hair follicles, and sometimes nails, caused by a T-cell mediated autoimmune mechanism. Current treatment modalities include corticostero...

Proton beam therapy is a globe preserving treatment method of choroidal melanoma. It is considered to be less harmful for the tissues around the tumour but the complications such as radiation retinopathy and neuropathy o...

Hip fractures in the elderly represent a significant cause of morbidity and mortality. A considerable proportion of these patients are on antiplatelet medications, such as aspirin (Ecospirin) and clopidogrel (Clopitab), ...

ObjectiveHigh-risk localized prostate cancer is often associated with a higher risk of disease progression post-surgery. While radical prostatectomy (RP) is a cornerstone treatment, neoadjuvant chemohormonal therapy (CHT...

Abstract Background Young and middle-aged patients who simultaneously present with depression and obesity and who have undergone laparoscopic sleeve gastrectomy still face significant difficulties accessing mental health...

Introduction and aims: Subtype-specific differences in patient-reported outcomes (PROs) following periodontal therapy for gingivitis remain poorly defined. This study compared changes over time in clinical parameters, or...

Background: This cross-sectional observational study analyzed data from routine clinical practice to compare outcomes across independent treatment duration cohorts (3, 6, and 9 months). Methods: This retrospective cohor...

Existem evidências de que estrogênios, progesterona e androgênios têm efeito modulador sobre as respostas imunes humoral e celular. Estes efeitos ocorrem via interações imuno-neuroendócrinas, envolvendo a hipófis...

Context. Meditation incorporation helps to fight against disorders such as depression, stress, and anxiety. Specifically, few studies have studied Osho's Active Meditation on young people, but observed evidence using pas...

Abstract Background To evaluate the efficacy of an Internet-based Cognitive Behavioral Therapy (ICBT) program in improving kinesiophobia, exercise adherence, pain intensity, lumbar function, and spinal alignment paramete...

Abstract Background Patients with relapsed/refractory diffuse large B-cell lymphoma (R/R DLBCL) who failed bispecific antibody (BsAb) therapy face an extremely poor prognosis, necessitating exploration of effective salva...

Cancer therapy and food preservation both face significant challenges related to stability, targeted delivery, safety, and efficiency of active compounds. Biopolymer-based nanoparticles, particularly those derived from c...