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Abstract. With levels of medicine and pharmacology individualization constantly increasing, the scientific community is becoming seriously concerned about the safety of existing and developing drugs for the pediatric pop...

Abstract Traditional medicinal plants play a crucial role in paediatric healthcare, especially in underdeveloped countries where access to modern medicine is limited. This review synthesizes ethnobotanical, pharmacologic...

IntroductionVirtual control groups (VCGs) are proposed as a means to reduce reliance on live animals in preclinical toxicology studies. Despite the potential benefits of VCGs, concerns remain regarding their comparabilit...

Background and Aim: Effective disinfection is critical for controlling pathogenic and opportunistic microorganisms in livestock environments. Didecyldimethylammonium chloride (DDAC), a quaternary ammonium compound, is wi...

In this study, the content of Pb, the physico-chemical and biological parameters in soils, and the metal transfer to vegetative and reproductive Sorghum bicolor plants were evaluated along with their relationship with th...

A few years ago, the 2-hydroxy-4´-methoxy dibenzoylmethane (DBM11) molecule was synthesized and studied as a replacement for avobenzone (AVB, butyl methoxydibenzoylmethane) because of the latter's instability under UVA ...

Abstract Polycyclic aromatic hydrocarbons (PAHs) are persistent organic pollutants of global concern due to their widespread occurrence, environmental persistence, and well-documented adverse effects on human health. In ...

Triclosan (TCS) is widely applied to daily necessities as a chemical bacteriostatic agent. Environmental TCS levels have increased significantly following the coronavirus disease 2019 pandemic, posing a potential threat ...

Abstract Assessment of the toxicity of insoluble particulate matter (PM) in the atmosphere is crucially important. However, because of challenges associated with extracting insoluble PM from filters, the toxicity of inso...

Abstract Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of citric acid anhydrous and citric acid monohydrate produced by fermentation with Aspe...

Fuzi, the processed lateral root of Aconitum carmichaelii Debeaux (Ranunculaceae), is a vital yet highly toxic botanical drug in traditional Chinese medicine. However, its narrow therapeutic window, driven by highly toxi...

The parenteral administration of antivenoms is the cornerstone of snakebite envenoming therapy. Efforts are made to ensure that antivenoms of adequate efficacy and safety are available world-wide. We address the main iss...

ObjectiveTo assess the quality of the literature related to the carcinogenicity of perfluorooctane sulfonic acid （PFOS） using the weight of evidence method， and to evaluate its carcinogenic risk through the dose-re...

Abstract The Panel on Food Additives and Flavourings (FAF) of the European Food Safety Authority was requested to consider evaluations of flavouring substances assessed since 2000 by the Joint FAO/WHO Expert Committee on...

ABSTRACT Background Leonurine (LEO), a bioactive alkaloid derived from the Leonurus genus, exhibits diverse pharmacological activities including uterotonic, antioxidant, anti‐inflammatory, antiapoptotic, Antitumor, and...

ObjectiveTo systematically evaluate the toxic effects and potential health hazards of butyl benzyl phthalate （BBP）， thereby providing a scientific basis for its risk management and control.MethodsLiterature publish...

Abstract Tenebrio molitor larvae, as known as edible insects, has advantages of being rich in protein, and has been recognized as a suitable alternate protein source for broiler and pig feed. Moreover, given their abilit...

Background: The release of micro- and nanoplastics (MNPs) from tea bags during brewing is a significant, recently identified source of potential human exposure. This systematic review collected global research published ...

Abstract In recent times, both in vitro and in vivo studies have demonstrated toxicological and pathological evidence of microplastic exposure in neurological dysfunction and diseases. The mechanistic linkage of micropla...

El D-003 es una mezcla de ácidos alifáticos primarios de muy alto peso molecular purificada de la cera de caña, con efectos hipolipemiante y antiagregante plaquetario demostrados experimental y clí- nicamente. Los es...

Bouchea fluminensis (Vell.) Mold. es una especie vegetal de la familia de las Verbenáceas, popularmente conocida como "falso gervão" or "gervão de folha grande". Se encuentra principalmente en Sudamérica. Se realizó...

La tintura de propóleos es un fitofármaco que tiene asociados diversos efectos farmacológicos: acción antimicrobiana, analgésica, antinflamatoria, antioxidante y cicatrizante. Según las normativas establecidas por ...

Xylitol is a widely studied sugar with therapeutic properties and is effective against microorganisms. Despite a variety of toxicological data being available about this compound, dermal toxicological tests cannot be fou...

O presente trabalho relata a realização de um levantamento etnofarmacológico entre os moradores de São Luiz Gonzaga (Rio Grande do Sul, Brasil), visando levantar junto à comunidade quais e para que fins as plantas e...