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Abstract Background Epidemiological data consistently associate low vitamin D status with elevated cardiovascular risk, yet causal mechanisms remain contested. Methods This review synthesized evidence through a protocol-...

Background: A new generation P2Y12 receptor inhibitor (ticagrelor) is recommended in current therapeutic guidelines to treat patients with coronary heart disease (CHD). However, it is unknown if ticagrelor is more effect...

Abstract The application of Bayesian statistics in pivotal clinical trials has gained increasing attention, particularly for underpowered confirmatory trials such as those in pediatric and rare disease populations. Bayes...

Although the literature on clinical trial methodology is quite robust, the voices of study staff as key influencers of this process are lacking, particularly for rural and underserved pediatric clinical trials. Using qua...

Abstract Objective To describe healthcare resource use in rural Mozambique among postpartum women with HIV, their seroconcordant male partners (MPs), and their infants to estimate costs and inform program planning. Metho...

BackgroundRandomised controlled trials (RCTs) are widely accepted as the preferred study design for evaluating healthcare interventions. When the sample size is determined, a (target) difference is typically specified th...

ObjectiveTo assess the effects of peri-abortion contraceptive counseling interventions.MethodsWe performed a systematic review of randomized controlled trials (RCTs) that compared the effect of different types of peri-ab...

Abstract Background Childbirth can be psychologically traumatic for up to 44% of women. Determinants of a negative childbirth experience include loss of control and lack of emotional support or interaction with obstetric...

Sustainability is becoming a significant concern in academic institutions worldwide. This issue is critical in Asian countries, which are more vulnerable to adverse environmental effects. Universities in these regions ca...

How can we measure the effects of campaign events? We estimate how voters respond to a prominent campaign scandal—Donald Trump being convicted of 34 felony counts of falsifying business records—using data from a larg...

Abstract Background There has been a recent push for biomedical research to incorporate more demographically, ethnically, and medically diverse cohorts – individuals whom the NIH designates as “underrepresented in bi...

Abstract Background Population ageing presents increasing challenges for health systems. Identifying complex needs and planning individualized care through Comprehensive Geriatric Assessment (CGA), promoting intergenerat...

ABSTRACT Background and Aims Cardiovascular disease (CVD) remains the leading global cause of death, with 80% of deaths occurring in low‐ and middle‐income countries (LMICs). Improving access to screening and early d...

Abstract Modern antenna design is an intrinsic undertaking. It relies heavily on expert knowledge and computational tools, especially electromagnetic (EM) simulation software. The most daunting phase is the development o...

Purpose – This study aimed to develop and evaluate CircuitPintar, a website-based learning medium designed to improve the competencies of vocational high school students in the Basic Electrical Theory element of the El...

Purpose – this study differs from previous research in that it focuses on developing the DCALL model in writing learning. The main target is students' writing skills in any text, supported by an application integrated ...

Abstract Background Persons with disabilities (PWD) face a higher risk of abuse compared to individuals without disabilities and encounter numerous barriers to seeking help. This scoping review examines the evidence on h...

Purpose – This study aims to develop an innovative learning medium, KOPDAS (Smart Comic Puzzle), as a literacy tool based on read-aloud activities to foster reading interest among elementary school students and to exam...

Background: Anaemia remains a major public health concern in pregnancy and is associated with adverse maternal and perinatal outcomes. Low-dose aspirin (LDA) is widely prescribed to reduce the risk of preeclampsia (PE),...

Background: Carpal tunnel syndrome (CTS) is the most prevalent entrapment neuropathy and represents a major functional and socioeconomic burden. Although surgical decompression remains the gold standard for advanced dise...

To analyze the effects of temperature, concentration, and reaction time on the denitration rate of double based spherical gun propellant (DBSGP) and to investigate the denitration reaction-diffusion coupling process for ...

Preeclampsia represents an unmasking of underlying vascular and metabolic vulnerability during the physiologic stress of pregnancy. Current first-trimester screening relies heavily on body mass index which incompletely c...

Abstract It is becoming more well acknowledged that oxidative stress is a crucial component that connects the hormonal, metabolic, and reproductive aspects of polycystic ovarian syndrome (PCOS). A more holistic and natur...

Indonesia is the second-largest instant noodle consumer in the world after China, with consumption reaching more than 12 billion packs per year. This high demand drives the need for innovation in the production process, ...