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Abstract Background and objectives The under-representation of vulnerable groups in clinical trials, including persons with disabilities, could affect the applicability of trial findings to real-world public health inter...

Abstract Background Alkaline phosphatase (ALP) activity in gingival crevicular fluid (GCF) reflects localized periodontal and alveolar bone remodeling during orthodontic tooth movement. Although ALP changes have been inv...

Abstract Background Previous studies have evaluated traditional Chinese medicine (TCM) clinical randomized controlled trial (RCT) literature broadly, but they have provided limited depth in evaluating the specific aspect...

ABSTRACT Background Regional anesthesia, while offering numerous clinical advantages, can paradoxically heighten intraoperative anxiety and stress due to patients remaining conscious throughout surgical procedures. Objec...

ObjectiveTo evaluate the effects of various transcranial magnetic stimulation (TMS) parameters—including stimulation duration, intensity, pulse number, frequency, and target region—on pain scores in patients with neu...

Abstract Background Dogs with immune‐mediated disease often receive glucocorticoids with clopidogrel, but ulcerogenic effects of current protocols are unknown. Hypothesis/Objectives To compare gastrointestinal endoscop...

Abstract Introduction Non-invasive brain stimulation (NIBS) as monotherapy has been increasingly used to enhance the activity of brain networks. However, it is unclear whether a combination of distinct NIBS approaches ...

Background This study aimed to compare the acute and residual physiological responses elicited by three different priming exercise strategies, including high-intensity priming exercise (HIPE), low-intensity priming exerc...

Abstract Background/objectives Cardiovascular diseases (CVDs), particularly myocardial infarction (MI) and heart failure (HF), remain global causes of morbidity and mortality, despite the current treatment options. Stem ...

Abstract Juvenile idiopathic arthritis (JIA) comprises a heterogeneous group of childhood-onset inflammatory arthritides that remain challenging to treat. An expanding range of biologic and targeted synthetic disease-mod...

Abstract Background In the neurorehabilitation framework of treadmill-based robot-assisted gait training (t-RAGT), a threefold relationship among physiotherapist (Pht), patient (Pt), and the selected robotic device shoul...

Abstract Background Desoxycorticosterone pivalate (DOCP) is a commonly used mineralocorticoid replacement for dogs with primary hypoadrenocorticism (HA), but manufacturer‐recommended dosing protocols can be cost‐proh...

Abstract Background Traditionally, 6‐month courses of prednisolone are used to treat steroid‐responsive meningitis‐arteritis (SRMA), but this medication is associated with adverse effects that can lead to poor qual...

Abstract BackgroundChronic musculoskeletal pain (CMP) imposes a significant psychological, physical, and emotional burden on millions of adults in the United States. A challenge in treating CMP is its tendenc...

Abstract Background Urethral obstruction (UO) is a common complication of feline idiopathic cystitis (FIC). Robust treatment recommendations to prevent its recurrence are scarce. Objectives To evaluate meloxicam treatmen...

Abstract BackgroundIndividuals with schizophrenia or bipolar disorder face a significantly elevated risk of obesity, primarily due to weight gain associated with psychiatric medications and lifestyle factors....

BackgroundExercises that involve increasing the speed of movements are beneficial for individuals with Parkinson disease (PD) and have the potential to reduce bradykinesia. High-speed bodyweight resistance training is ac...

BackgroundOpioid overdose remains a leading cause of preventable death in the United States. Existing approaches to identify individuals at elevated risk rely on imprecise rule-based criteria that misclassify patients’...

Abstract BackgroundTripterygium glycoside tablets (TGTs), a traditional Chinese medicine–based therapy and a type of conventional synthetic disease-modifying antirheumatic drug (csDMARD), have shown promise...

Abstract Objective The aim of the present study is to list the published clinical trials on coronavirus disease 2019 (COVID-19) vaccines, to describe the mechanism of action of the identified vaccines, and to identify p...

Objective: To evaluate the efficacy and safety of Ganmai Dazao (GMDZ) decoction alone and in combination with antidepressant medication or psychotherapy for depression. Methods: We searched seven electronic databases fro...

Abstract This correspondence marks the 10-year milestone of InsulinAPP, a Brazilian-developed electronic glycemic management system (eGMS) designed to support inpatient insulin therapy. Initially published in 2015, Insul...

ObjectiveThis review summarizes the current evidence on the impact of isolated antiphospholipid antibody positivity (IAAP) on pregnancy outcomes. It analyzes risk differentials across antibody subtypes, synthesizes the u...

Abstract Tick control represent a great challenge to animal health. The objective of this study was to evaluate the efficacy of acaricidal compounds against Rhipicephalus microplus from dairy cattle systems in Paraná St...