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Aims: Tenosynovial giant cell tumour (TGCT) management is variable across the UK. Our aim was to examine these differences in clinical practice and develop consensus statements regarding the management of TGCTs. Methods:...

Introduction: The American College of Radiology (ACR) Bone-Reporting and Data System (Bone-RADS) gave a structured framework for assessing and reporting bone tumours. Aim: To evaluate the diagnostic performance of the...

Introduction. Basal cell carcinoma is the most common tumour of the eyelids and periocular region throughout the world. BCC represents 90 % of malignant tumours of the eyelids, predominantly in the male population. The i...

We report a rare case of left atrial myxoma in a 70-year-old female presenting with exertional dyspnoea and palpitations. Echocardiography demonstrated a pedunculated mass attached to the interatrial septum. Surgical exc...

Background: Myeloid sarcoma (MS) is a solid malignant tumour associated with infiltration of immature myeloid precursor cells in an extramedullary site. The term MS has replaced the term granulocytic sarcoma and chloroma...

Conjunctival vascular tumours are rare in adults and often pose diagnostic challenges due to overlapping features between haemangioma and lymphangioma. A 22-year-old male presented with painless, slowly enlarging mass in...

ABSTRACT: Introduction and aims: To provide the research progress on the cGAS-STING signalling pathway and its related roles in various oral diseases. Methods: We reviewed the recent research on cGAS-STING in PubMed. Th...

Abstract Pheochromocytomasand paragangliomas (collectively referred as PPGLs) are highly heritable neoplasms arise from chromaffin cells of neural crest tissues; 40% of patients with PPGLs harbour germline pathogenic var...

The aim of this study was to describe the use of acoustic radiation force impulse (ARFI) elastography in the evaluation of testicular disorders in dogs. Eighteen dogs with testicular disorders (thirty-six testicles) were...

Abstract Intraoperative nerve monitoring (IONM) provides real-time nerve feedback and easy identification, guiding surgical decisions in thyroid and parathyroid procedures. We assessed the practical implementation of the...

One of the deadliest diseases that can affect children and adults is a brain tumour. A brain tumour is the abnormal growth of cells in the brain or near it. Commonly, there are two types of tumours: malignant (cancerous)...

The treatment of paediatric low-grade gliomas has been previously controversial as to whether upfront surgery or a conservative approach should be utilised, with a recent paradigm shift favouring biopsy or resection, if ...

ABSTRACT: Introduction and aims: Oral squamous cell carcinoma (OSCC) is a common malignant tumour of the head and neck region. In recent years, the relationship between pyroptosis and tumours has received increasing att...

Dermatitis herpetiformis is a rare, chronic, autoimmune blistering disease with hypersensitivity to gluten with the presence of intense pruritus. Symptoms of the disease are symmetrical, polymorphic skin lesions in a t...

Abstract Background The tumour microenvironment and systemic inflammatory environment are related to the diagnosis, treatment and prognosis of various tumours. This study aimed to evaluate the clinicopathological signifi...

Objectives: To characterize the proliferative and immunophenotypic profiles of salivary gland mucoepidermoid carcinoma (MEC) and to explore their associations with clinicopathologic features, tumour microenvironment (TME...

We reveal a coordinating role for Cx32-mediated cell–cell communication in maintaining mitotic-quiescence and limiting migration-associated TGFβ signalling, extracellular matrix remodelling and mesenchymal-like change...

Abstract Introduction Bladder cancer (BLCA) is a malignant tumour that occurs on the mucosa of the bladder. It accounts for the first place in the incidence of genitourinary tumours in China. BLCA is characterized by hig...

Curcumin (diferuloylmethane), a polyphenolic compound derived from the spice plant Curcuma longa, displays multiple actions on solid tumours including anti-angiogenic effects. Here we have studied in rodent and human pit...

Previous studies on a murine model have demonstrated that the administration of Lactobacillus helveticus and Lactobacillus casei inhibits the development of fibrosarcoma and colon carcinoma, respectively. The aim of this...

Introduction: Head and Neck Squamous Cell Carcinoma (HNSCC) is among the most prevalent malignancies worldwide, with poor survival outcomes despite advances in multimodal therapy. Tumour immune evasion through the Progra...

Hemozoin (Hz) is a crystalline by-product, which is produced when the Plasmodium species destroy haemoglobin, and it is commonly recognised that it leads to how our bodies respond to malaria. Although we understand prett...

Hexachlorobenzene (HCB) is an organochlorine pollutant widely distributed in the environment around the entire world. Previous reports from our group and others have demonstrated that this compound is as an endocrine dis...

Abstract Background To improve the visualisation of colorectal cancer (CRC) and its metastatic lymph nodes (LNs), we developed a second near-infrared window (NIR-II; 1000–1700 nm) fluorescent probe using a monoclonal ...