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Abstract The core pathological mechanisms of diabetic microvascular diseases, such as nephropathy, diabetic retinopathy (DR), and neuropathy, involve the dysfunction and loss of microvascular endothelial cells (ECs), vas...

Exosomes, a specialized class of extracellular vesicles, exhibit significant therapeutic potentials for neurological disorders, in particular for vascular dementia (VaD). VaD is the second most common form of dementia, c...

Background. Physical activity is a fundamental component of health, prevention, and education; however, in selected high-risk populations, safe exercise prescription remains a major challenge. Vascular Ehlers–Danlos sy...

BackgroundSystemic sclerosis (SSc) is characterized by a complex and heterogeneous interplay between vascular dysfunction, immune activation, and progressive fibrosis. Despite advances in molecular characterization, ther...

Introduction. Necrobiosis lipoidica (NL) is a granulomatous skin disease of still only partially known pathogenesis. Microangiopathy is considered as one of the most important processes in NL, and vascular endothelial ...

Kalatop–Khajjiar Wildlife Sanctuary represents one of the ecologically significant forested landscapes of the northwestern Himalaya; however, updated and systematic documentation of its vascular flora has remained limi...

Abstract Current treatment for atherosclerotic cardiovascular diseases (ASCVD) mainly focuses on the modification of systemic risk factors, such as hyperglycemia and hyperlipidemia. Despite significant efforts and expans...

Cardiovascular disease and diabetic nephropahty account for much of the morbidity and mortality associated with diabetes mellitus. Genotypic abnormalities of the reninangiotensin system have been suggested as a risk fact...

Avaliaram-se os aspectos clínicos do entrópio de desenvolvimento em filhotes de cães da raça Shar Pei. Utilizaram-se 50 animais com idades entre 18 e 128 dias, que apresentavam graus variáveis de inversão palpebral...

This study was conducted to investigate the ability of green tea as antioxidant and antiatherogenic in female rats after treated with 0.5o/o of H20 2 in order to induced atherosclerosis. The results showed capability o...

OBJECTIVE: To investigate the relationship between early stage hypertensive retinopathy (HTRP) and endothelial dysfunction (ED) in atherogenesis. MATERIAL and METHODS:Atotal of 99 subjects consisting of 73 patients di...

Abstract Background Carotid atherosclerosis is a kind of systemic atherosclerosis in the carotid arteries. It remains one of the leading causes of ischemic stroke. However, the efficiency of treatment is insufficient. Th...

Abstract Background Congenital malformations in domestic cats are traditionally considered uncommon; however, recent evidence suggests they may represent an underrecognized cause of neonatal mortality. Most reported anom...

Abstract The reduction of nitric oxide (NO) bioavailability in the endothelium induces endothelial dysfunction, contributing to the development of hypertension. Although Lactobacillus consumption decreases blood pressure...

ABSTRACT Bactris trunks are made entirely by long sustained primary growth so that mechanical properties develop progressively as the trunk matures. Anatomical features vary throughout the stem so that one small sample i...

Purpose of review: One of the most important challenges in the intestinal (ITx) and multivisceral transplant (MVTx) is to achieve a successful abdominal wall closure. Recent findings: A tension-free primary closure shoul...

Objective: To summarize and contextualize current and future perspectives in the surgical treatment of lymphedema, exploring new techniques and technologies, integrated treatment modalities, and their real-time clinical ...

The enzyme heme oxygenase-1 (HO-1) is pivotal in reproductive processes, particularly in placental and vascular development. This study investigated the role of HO-1 and its byproduct, carbon monoxide (CO), in trophoblas...

IntroductionDisrupted rest-activity rhythm (RAR), an accelerometer-derived measure of the strength and temporal organization of daily behavioral rhythms, has been linked to multiple adverse health outcomes. Given that th...

Pulmonary hypertension (PH) is a severe cardiopulmonary disorder characterized by pulmonary vascular remodeling, which leads to increased pulmonary vascular resistance (PVR), right ventricular (RV) hypertrophy, and ultim...

BackgroundAlzheimer’s disease (AD), the most prevalent dementia, is primarily underpinned by the amyloid cascade hypothesis. Passive Aβ immunotherapy effectively reduces cerebral Aβ deposition but is limited by sever...

We report a case of the development of bilateral glaucoma after flow-diverting stent placement in the left internal carotid artery (ICA) in the projection of the aneurysm neck. The case confirms the importance of a multi...

The South American water rat Nectomys squamipes is a wild mammal reservoir of Schistosoma mansoni in Brazil. In the present study, wild rodents were collected in the field and categorized into two groups: infected and un...

Anemia is one of the common chronic renal failure (CRF) complications. Reduced renal erythropoietin (EPO) production and a shortened life span of erythrocytes due to uremic environment and iron deficiency are the main ca...