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A simple isocratic method for quantification of hydroxyzine dihydrochloride by HPLC with UV detection at 232 nm in syrup has been developed and validated. Separation was achieved on a C18 column (250 x 4.6 mm, 5 μm) mai...

Hydroquinone (HQ) is a drug reported to possess manifold biological activities. HQ is highly unstable into various topical vehicles, presenting low topical bioavailability and a relevant level of toxicity. The Pluronic®...

A simple HPLC method was developed to study the pharmacokinetics of tobramycin in rat after intravenous administration. The plasma samples were deproteinized with acetonitrile after addition of the internal standard, net...

The aim of this work was to identify the characteristics of the drug information provided by the Drug Information Center (DIC) of a university hospital. A cross-sectional study was conducted, identifying the profile of i...

El acceso al tratamiento para el alivio del dolor severo implica que el fármaco necesario para tal fin esté a disposición de aquel que lo necesita en tiempo y forma. Un fármaco puede estar disponible en un país pero...

Montanoa tomentosa has been used for at least last five centuries in traditional medicine in Mexico as a remedy for reproductive impairments. The accumulation of diterpenic acids in M. tomentosa leaves was determined. Us...

El presente escrito surge de un problema clínico en el trabajo con familias de pacientes en situación de enfermedad avanzada y con pronóstico de terminalidad. En estos casos, la presencia de niños en la familia suele...

Fil: Salomón Tarquini, Claudia. Universidad Nacional de La Pampa; Argentina. Fil: Salomón Tarquini, Claudia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Entre los proyectos de ocupación te...

Besides enteral tubes are used for administration of enteral feeding, they are also alternative ways to manage drugs in patients with impaired swallowing. When the drug is not available in the oral liquid form, the extem...

The objective of this study was to estimate the prevalence of adverse drug reactions (ADR) related to hospital admission of elderly people, identifying the use of potentially inappropriate medication (PIM) , the ADR and ...

Multiple drug administration increases chances of drug interaction, altering the responses of drugs either increasing or decreasing pharmacological effects, or generating a new pharmacological response. Generally drug in...

This work is focused on the development of a new particulate drug delivery system using sodium alginate (SA) and modified hydrophobic hydroxyl propyl methyl cellulose (HPMC, 60L grade) containing diclofenac as a model dr...

El objetivo de esta nota reflexiva es invitar a pensar esta conceptualización de la naturaleza humana y la diversidad cultural impacta sobre la formación de los agentes de salud. Hay dos implicancias de esta perspectiv...

Cuentan las abuelas y los abuelos, cuando por las noches se reúnen a platicar historias alrededor del fuego que calienta el cuerpo y el corazón, que cuando el mundo este se comenzó, fueron nacidas también distintas c...

Cat's claw (Uncaria tomentosa (Willd) DC) is an alkaloid rich-liana from the Peruvian Amazon rainforest. Regarding several oxindole alkaloids from cat's claw bark, the isomerization induced by pH, temperature and solvent...

A bioanalytical micromethod was described for the quantification of amphotericin B in plasma by HPLC. The method showed high absolute recovery, good linearity (0.1-10.0 μg/mL, r2 = 0.999), sensitivity (limits of quantif...

The objective of this study was to evaluate preliminary stability, as well as to validate an analytical method for in vitro skin permeation study of a gel containing tincture of Calendula officinalis L., aiming at the im...

El anexo de este número pretende describir a la población que atendió el Servicio de Medicina Paliativa del HIGA “Dr. Rodolfo Rossi” de La Plata en el periodo enero/junio 2010 a partir de su comparación con la po...

Calotropis gigantea (Linn.) R.Br. (Asclepiadaceae), commonly known as milkweed or swallow- wort, is found chiefly in wasteland throughout India. It has been reported as a traditional folkloric medicine in treatment of as...

Several species of the Polygonum genera are collectively known in Brazil under the name "erva-de-bicho". In tradicional medicine, these species often mistaken for each other and are probably used for the same therapeutic...

Natural products play a significant role in human health in relation to the prevention and treatment of inflammation conditions. Although not fully understood, several action mechanisms are proposed to explain in vivo in...

D-002, a mixture of six beeswax alcohols, with gastroprotective and anti-inflammatory effects, was compared with naproxen, aspirin and their combined therapy in rats with cotton pellet granuloma. After pellet implantatio...

Ibicella lutea (Lindl.) Van Eselt. (Martyniaceae) is the sole species of the genus Ibicella from the small Martyniaceae family comprising just 3 genera (Martynia, Proboscidea and Ibicella) with 13 species. In Uruguay, wh...

Nyctanthes arbortristis Linn. (Oleaceae) is one of the well known medicinal plants. It is commonly known as "Night Jasmine". As traditionally the plant is used in the treatment of asthma and cough it was our objective to...